Difen Plus 50mg/325mg Tablet is a combination of two medicines. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Difen Plus 50mg/325mg Tablet should be taken in an empty stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, flatulence, indigestion, diarrhea, and constipation. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Difen Plus Tablet

Pain relief

Benefits of Difen Plus Tablet

In Pain relief

Difen Plus 50mg/325mg Tablet gives relief from pain in inflammatory conditions that affect muscles and joints such as rheumatoid arthritis, osteoarthritis and back pain. It also helps manage toothache, or pain in the ear and throat. It works by blocking the action of certain chemicals that causes pain and swelling. Pantoprazole, an active constituent present in Difen Plus 50mg/325mg Tablet prevents acidity that may occur due to the painkiller.

Side effects of Difen Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Difen Plus

Nausea
Flatulence
Indigestion
Diarrhea
Constipation

How to use Difen Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Difen Plus 50mg/325mg Tablet is to be taken empty stomach.

How Difen Plus Tablet works

Difen Plus 50mg/325mg Tablet is a combination of two medicines: Diclofenac and Pantoprazole which relieve pain. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain, fever and inflammation (redness and swelling). Pantoprazole is a proton-pump inhibitor which prevents damage to the stomach lining caused by Diclofenac.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Difen Plus 50mg/325mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Difen Plus 50mg/325mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Difen Plus 50mg/325mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Difen Plus 50mg/325mg Tablet may cause side effects which could affect your ability to drive.
Difen Plus 50mg/325mg Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.

Kidney

CAUTION

Difen Plus 50mg/325mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Difen Plus 50mg/325mg Tablet may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Difen Plus 50mg/325mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Difen Plus 50mg/325mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Difen Plus Tablet?

If you miss a dose of Difen Plus 50mg/325mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Difen Plus 50mg/325mg Tablet

₹1.85/Tablet

Diclorokk P 50mg/325mg Tablet

Rokkwinn Healthcare

₹3.86/tablet

109% costlier

Dilon Plus 50mg/325mg Tablet

Benzon Remedies

₹6.36/tablet

244% costlier

Diclosia P 50mg/325mg Tablet

Sia Pharma Pvt Ltd

₹6.76/tablet

265% costlier

Diclolex P 50mg/325mg Tablet

Med Lex Pharmaceutical

₹11.7/tablet

532% costlier

Erafenac P 50mg/325mg Tablet

Eracure Healthcare

₹3.92/tablet

112% costlier

Quick tips

Difen Plus 50mg/325mg Tablet reduces pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.
It may also be used to relieve pain in tooth, lower back, ear and throat.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious side effects.
It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how Difen Plus 50mg/325mg Tablet affects you.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long duration.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

One of my teeth is sensitive. It some times pains

Dr. Abhijit Gambhir

Dental Surgery

sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

Top Rheumatologists

4.9 ★

5 ★

4.7 ★

MBBS, DNB, MD, Fellowship, Fellowship

4.7 ★

Dr. Indrajit Agrawal

MBBS, MD, Fellowship

4.6 ★

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Diclofenac. Rouse Boulevard, Philadelphia: Iroko Pharmaceuticals; 1998 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) Available from:
Pantoprazole. Konstanz, Germany: Wyeth Pharmaceutical; 2000 [revised Mar. 2012]. [Accessed 28 Mar. 2019] (online) Available from:
Diclofenac. Daventry, Northamptonshire: Dexcel Pharma Ltd.; 1996 [revised 20 Dec. 2017]. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Pantoprazole. [Accessed 23 Apr. 2019] (online) Available from:

Marketer details

Name: Orison Pharmaceuticals

Address: No-51, Industrial Estate, Ambala Cantt, Haryana, 133006, India

Country of origin: India

₹18.5

Inclusive of all taxes

MRP₹18.85 2% OFF

10.0 tablets in 1 strip

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