Donetine 5 Tablet
Prescription Required
Product introduction
Donetine 5 Tablet is used to treat mild to moderate dementia in Alzheimer’s disease, a progressive illness that gradually affects memory and thinking. It does not cure this illness but may help improve memory, awareness, and other symptoms.
Your doctor will explain how to take Donetine 5 Tablet. You may take it with food, preferably at night before going to bed. Follow the instructions carefully to get the most benefit. The dose may change from time to time to suit your individual needs. It can take up to a few weeks for symptoms to improve so keep taking your medicine regularly. You should not stop taking this medicine without consulting your doctor.
Some common side effects of this medicine include nausea, diarrhea, insomnia, vomiting, muscle cramps, fatigue, weight loss (anorexia), headache, loss of appetite, common cold, urinary incontinence, and rash. Drink plenty of fluids to keep yourself hydrated. You may have side effects more often when you start your treatment or when your dose is increased. Usually, the side effects will slowly go away as your body gets used to the Donetine 5 Tablet. If they are severe or will not go away, you should contact your doctor.
Before using Donetine 5 Tablet, you should tell your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma. It may also affect, or be affected by, some other drugs you are using so let your doctor know what these are to be safe. During pregnancy, this medicine should only be taken if it is advised.
Your doctor will explain how to take Donetine 5 Tablet. You may take it with food, preferably at night before going to bed. Follow the instructions carefully to get the most benefit. The dose may change from time to time to suit your individual needs. It can take up to a few weeks for symptoms to improve so keep taking your medicine regularly. You should not stop taking this medicine without consulting your doctor.
Some common side effects of this medicine include nausea, diarrhea, insomnia, vomiting, muscle cramps, fatigue, weight loss (anorexia), headache, loss of appetite, common cold, urinary incontinence, and rash. Drink plenty of fluids to keep yourself hydrated. You may have side effects more often when you start your treatment or when your dose is increased. Usually, the side effects will slowly go away as your body gets used to the Donetine 5 Tablet. If they are severe or will not go away, you should contact your doctor.
Before using Donetine 5 Tablet, you should tell your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma. It may also affect, or be affected by, some other drugs you are using so let your doctor know what these are to be safe. During pregnancy, this medicine should only be taken if it is advised.
Uses of Donetine Tablet
Side effects of Donetine Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Donetine
- Common cold
- Urinary incontinence
- Rash
- Nausea
- Diarrhea
- Insomnia (difficulty in sleeping)
- Weight loss
- Accidental injury
How to use Donetine Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Donetine 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Donetine Tablet works
Memory loss in Alzheimer’s disease occurs due to disturbances of signal transmission in the brain. Donetine 5 Tablet is a cholinesterase inhibitor. It works by increasing the levels of a chemical messenger (acetylcholine) involved in transmmission of nerve signals. This improves memory and thinking.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Donetine 5 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Donetine 5 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Donetine 5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Donetine 5 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Donetine 5 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Donetine 5 Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Donetine 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Donetine 5 Tablet may be needed. Please consult your doctor.
What if you forget to take Donetine Tablet?
If you miss a dose of Donetine 5 Tablet, skip it and continue with your normal schedule. Do not double the dose.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- You have been prescribed Donetine 5 Tablet to slow down the progression of Alzheimer's disease.
- It does not cure Alzheimer's disease but may help improve brain function and ability to do daily activities.
- Take it with or without food, preferably at night before going to bed.
- It may cause diarrhea, nausea, and vomiting. Drink plenty of fluids to keep yourself hydrated while taking Donetine 5 Tablet.
- Monitor your body weight regularly as both Donetine 5 Tablet and Alzheimer's disease can cause weight loss.
- Do not drive or do anything that requires mental focus until you know how Donetine 5 Tablet affects you.
- Be cautious while taking this medicine if you suffer from peptic ulcer as it may cause vomiting, stomach bleeding, stomach pain, or discomfort.
- Inform your doctor if you develop muscle tremors, especially if you have Parkinson’s disease.
- Inform your doctor if you experience seizures or convulsions while taking this medicine.
- You have been prescribed Donetine 5 Tablet to slow down the progression of Alzheimer's disease.
- It does not cure Alzheimer's disease but may help improve brain function and ability to do daily activities.
- Take it with or without food, preferably at night before going to bed.
- It may cause diarrhea, nausea, and vomiting. Drink plenty of fluids to keep yourself hydrated while taking Donetine 5 Tablet.
- Monitor your body weight regularly as both Donetine 5 Tablet and Alzheimer's disease can cause weight loss.
- Do not drive or do anything that requires mental focus until you know how Donetine 5 Tablet affects you.
- Be cautious while taking this medicine if you suffer from peptic ulcer as it may cause vomiting, stomach bleeding, stomach pain, or discomfort.
- Inform your doctor if you develop muscle tremors, especially if you have Parkinson’s disease.
- Inform your doctor if you experience seizures or convulsions while taking this medicine.
Fact Box
Chemical Class
Carbamate Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Cholinesterase Inhibitors
Interaction with drugs
Taking Donetine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Pilocarpine may increase the effect of Donepezil.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Donepezil may raise blood levels of Ramelteon.
Watch out for symptoms such as drowsiness, impaired movement, tiredness, nausea, palpitations, or numbness, and consult your doctor
If used together, Opipramol may oppose the effects of Donepezil.
If concurrent use is essential, please consult your doctor. They may monitor your treatment and adjust the doses a
If used together, Donepezil may oppose the effects of Oxybutynin.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observatio
Pilocarpine may increase the effect of Donepezil.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Patient concerns
FAQs
Why is Donetine 5 Tablet taken at night?
Donetine 5 Tablet is recommended to be taken before going to bed to reduce gastrointestinal side effects or nausea, which is commonly seen in some patients in the first few weeks of treatment.
Do the gastrointestinal side effects due to Donetine 5 Tablet persist for a long time?
Gastrointestinal side effects may appear during the first few weeks of treatment with Donetine 5 Tablet. This can be minimized by taking Donetine 5 Tablet at bedtime and with food. Generally, these side effects are mild and disappear within a few weeks with continued treatment.
How long does it take for Donetine 5 Tablet to start working?
Within the first month of treatment with Donetine 5 Tablet, you may experience improvement in thinking and remembering (cognitive effect). However, it may take about 12 weeks to see the full benefits.
When should Donetine 5 Tablet be stopped?
Do not stop Donetine 5 Tablet without consulting your doctor. This medicine only helps to control your condition but does not cure it. Therefore, it may take several weeks to show benefits, so do not be discouraged if you do not see an improvement straight away. But, in case your condition starts worsening and you feel that it is no longer helping you, then you should consult a doctor before stopping it.
For how long does Donetine 5 Tablet stay in your system?
Donetine 5 Tablet gets removed from the body very slowly. It takes about two weeks or more for Donetine 5 Tablet to be completely removed from the system.
Does Donetine 5 Tablet cause depression?
No, Donetine 5 Tablet does not cause depression. If you are experiencing symptoms, then it could be due to existing Alzheimer’s disease.
What if I take more than the prescribed dose of Donetine 5 Tablet?
Taking more than the recommended dose of Donetine 5 Tablet may cause vomiting, increased sweating or saliva production, slow heartbeat, dizziness, difficulty in breathing, seizures or fits, weakness, low blood pressure, convulsions, and inability to control your bowel motions or passing of urine (incontinence). You should seek immediate help from a doctor or emergency service of a nearby hospital.
I have been taking indomethacin for arthritis. Can I take Donetine 5 Tablet?
Donetine 5 Tablet does not interfere with the working of indomethacin, but indomethacin individually increases the risk of stomach bleeding when taken for a long time. Therefore, if you experience any symptoms of stomach bleeding, consult your doctor immediately.
Does Donetine 5 Tablet cause hallucinations?
Hallucinations are a common side effect of Donetine 5 Tablet, though not everyone is affected. Other common psychiatric side effects include agitation, aggressive behavior, nightmares, and abnormal dreams.
Who should not take Donetine 5 Tablet?
Donetine 5 Tablet should not be taken by patients who have hypersensitivity to Donetine 5 Tablet hydrochloride, piperidine derivatives, or to any active ingredients used in the medicine. Also, it should not be used during pregnancy unless clearly necessary.
Can it cause insomnia?
Yes, insomnia (sleeplessness) is a common side effect of Donetine 5 Tablet. Dizziness and fainting can also be seen as common side effects. Though these side effects are common, they do not occur in everyone.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Donepezil. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 199-202.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 426-27.
- Donepezil hydrochloride. Woodcliff Lake, New Jersey: Eisai Inc.; 1996 [revised Feb. 2012]. [Accessed 25 Jan. 2019] (online) Available from:
- Donepezil. Hatfield, Hertfordshire: Eisai Ltd.; 1997 [revised 11 May 2018]. [Accessed 25 Jan. 2019] (online) Available from:
- Donepezil hydrochloride. South Ruislip, UK: Aurobindo Pharma - Milpharm Ltd.; 2013 [revised 23 Nov. 2017] [Accessed 19 Jun. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
- Donepezil hydrochloride [Prescribing Information]. Mahabubnagar, Telangana: Hetero Labs Limited; 2023. [Accessed 20 June 2023]. (online) Available from:
- Donepezil Hydrochloride [Summary of Product Characteristics]. Dublin, Ireland: Pfizer Healthcare Ireland; 2023. [Accessed 20 June 2023]. (online) Available from:
Marketer details
Name: Matias Healthcare Pvt Ltd
Address: 101-104 GCP Business centre opp. Memnagar fire station Vijay cross road Memnagar Ahmedabad-380014 India
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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