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Donrab IV 20mg Injection

Prescription Required

Product introduction

Donrab IV 20mg Injection is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as acid reflux, indigestion, peptic ulcer disease, and some other stomach conditions associated with excessive acid production.

Donrab IV 20mg Injection is fast-acting and provides quick relief from acidity-related problems. It is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs).

This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Your doctor will decide the duration of treatment but you should keep on taking it as prescribed, even if your symptoms disappear quickly. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.

The most common side effects observed with this medicine include nausea, vomiting, headache, dizziness, flatulence, diarrhea, stomach pain, and thrombophlebitis (pain, redness, and swelling of the vein). These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Long-term use of this medicine may lead to an increased risk of side effects. For instance, using this medicine for more than 1 year may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.

Low blood magnesium levels (hypomagnesemia) have been observed in some people taking this medicine for 3 months or more. These reduced levels of magnesium may lead to tiredness, confusion, dizziness, muscle twitches, and an irregular heartbeat. Your doctor may monitor your magnesium levels to prevent this.

Donrab IV 20mg Injection is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy.

Uses of Donrab Injection


Side effects of Donrab Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Donrab

  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Flatulence
  • Diarrhea
  • Stomach pain
  • Thrombophlebitis

How to use Donrab Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Donrab Injection works

Donrab IV 20mg Injection is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Donrab IV 20mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Donrab IV 20mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Donrab IV 20mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Donrab IV 20mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Donrab IV 20mg Injection is safe to use in patients with kidney disease. No dose adjustment of Donrab IV 20mg Injection is recommended.
Liver
CAUTION
Donrab IV 20mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Donrab IV 20mg Injection may be needed. Please consult your doctor.

What if you forget to take Donrab Injection?

If you miss a dose of Donrab IV 20mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Donrab IV 20mg Injection
₹97.6/Injection
Razo IV Injection
Dr Reddy's Laboratories Ltd
₹110/injection
12% costlier
₹165.95/injection
68% costlier
₹152.47/injection
55% costlier
Veloz 20mg Injection
Torrent Pharmaceuticals Ltd
₹134.2/injection
36% costlier
Dazol 20mg Injection
Neon Laboratories Ltd
₹45/injection
54% cheaper

Quick tips

  • Your doctor will administer Donrab IV 20mg Injection as an injection into a vein.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Some healthy tips to prevent acidity from happening:
    • Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
    • Avoid alcohol and smoking.
    • Avoid eating late at night or before bedtime.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Long-term use of Donrab IV 20mg Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
  • Donrab IV 20mg Injection should be taken 1 hour before a meal, preferably in the morning.
  • It is a well-tolerated medicine and provides relief for a long time.
  • Some healthy tips to prevent acidity from happening:
    • Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
    • Avoid alcohol and smoking.
    • Avoid eating late at night or before bedtime.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
  • Long-term use of Donrab IV 20mg Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.

Fact Box

Chemical Class
Sulfinylbenzimidazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton-Pump Inhibitors

Interaction with drugs

Taking Donrab with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Rabeprazole may reduce blood levels of Erlotinib. Do not consume Erlotinib with Rabeprazole.
Rabeprazole may cause low magnesium levels in the body and increase the risk of Digoxin poisoning. Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your l... More
Rabeprazole may reduce blood levels of Cefpodoxime Proxetil. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Rabeprazole may reduce blood levels of Ketoconazole. Your doctor may monitor the effects of Ketoconazole along with your overall treatment and adjust the doses as per the observat... More
Ginkgo Biloba may reduce blood levels of Rabeprazole. Talk to your doctor if you notice any unusual symptoms.

Patient concerns

arrow
Moderate Throat Pain in left side Moderate Ear pain. Acid reflux too often
Dr. Vijay Verma
ENT
it may be due to acidity also you may have got some ulcer or infection in that region visit ent specialist near you for proper examination
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed
arrow

FAQs

What is Donrab IV 20mg Injection used for?

Donrab IV 20mg Injection is used for the treatment of stomach and intestinal ulcers (gastric and duodenal ulcers), reflux esophagitis or gastroesophageal reflux disease (GERD). It works by reducing the amount of acid made by your stomach and thus relieves your symptoms. Donrab IV 20mg Injection also prevents acidity associated with use of painkillers and stress ulcers in critically ill people. It is also used to treat a disease associated with excessive acid production in the stomach known as Zollinger Ellison syndrome (ZES). Donrab IV 20mg Injection is also helpful as a preanesthetic medication (medicine given just before anesthesia) to reduce the chances of aspiration related complications like lung injury.

What dietary changes should I make to get relief from acidity?

Donrab IV 20mg Injection is best taken 1 hour before a meal. You should avoid spicy and fatty foods while taking this medicine. It also helps to cut down on caffeinated drinks such as tea, coffee, and cola. Alcohol intake should also be avoided as it may worsen your symptoms.

Does Donrab IV 20mg Injection cause bone problems?

Yes, long-term use of Donrab IV 20mg Injection can cause thinning of bones, which is called osteoporosis. Donrab IV 20mg Injection decreases the calcium absorption leading to calcium deficiency and increases the risk of bone fractures of the hip, wrist, or spine. Take an adequate amount of calcium in your diet or take the supplements as advised by your doctor to avoid any bone problems.

What other lifestyle changes should I make to get maximum benefit of Donrab IV 20mg Injection?

You make see better results if you make certain dietary and lifestyle changes while taking Donrab IV 20mg Injection. Exercise regularly and eat healthily. You can consult your dietician to get a diet chart that suits you best. Eat at least 3 hours before sleeping to reduce the chances of aggravation of your symptoms at night. You should avoid spicy and fatty foods while taking this medicine. Refrain from caffeinated drinks such as tea, coffee, and cola. Alcohol intake and smoking should also be avoided as they may worsen your symptoms.

Can I take alcohol with Donrab IV 20mg Injection?

No, alcohol intake is not advised with Donrab IV 20mg Injection. Alcohol itself does not affect the working of Donrab IV 20mg Injection, but it can increase acid production. This may further cause worsening of your symptoms.

Can I take antacids along with Donrab IV 20mg Injection?

Yes, you can take antacids along with Donrab IV 20mg Injection. Take it 2 hours before or after you take Donrab IV 20mg Injection.

How long does it take for Donrab IV 20mg Injection to work?

Donrab IV 20mg Injection starts working within an hour of taking it and shows maximum benefit within two to four hours. You should start feeling better within 2 to 3 days but it may take up to 4 weeks to relieve your symptoms significantly.

Can I stop taking Donrab IV 20mg Injection if I feel better?

No, do not stop taking Rekool before completing the full course of treatment. You will start to feel better before your treatment is complete. Donrab IV 20mg Injection is given into a vein, only if oral administration is not possible, for upto 7 days. As soon as the person is able to take it orally, intravenous administration is stopped and oral form is prescribed. Take Donrab IV 20mg Injection only as prescribed by your doctor to get maximum benefit.

Is Donrab IV 20mg Injection safe?

Yes, Donrab IV 20mg Injection is relatively safe. Most of the people who take Donrab IV 20mg Injection do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefits.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 24 Jan. 2019] (online) Available from:External Link
  2. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Rabeprazole. [Updated 2019 Jun 3]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Bioris Pharmaceuticals
Address: NEAR FATEHGARH MOD, HANUMANGARH TOWN, HANUMANGARH, Rajasthan - 335513
Country of origin: India

97.6
Inclusive of all taxes
MRP98.5  1% OFF
1.0 Injection in 1 vial
SOLD OUT

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