Dotadic 250mg/50mg/325mg Tablet MR is a combination medicine used in the treatment of pain due to muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.
Dotadic 250mg/50mg/325mg Tablet MR should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.
Using this medicine can cause some common side effects such as nausea, vomiting, heartburn, stomach pain, diarrhea, loss of appetite, and dryness in the mouth. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.
The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. To make sure it is safe for you, let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using the medicine.
Uses of Dotadic Tablet MR
Treatment of Pain due to muscle spasm
Benefits of Dotadic Tablet MR
In Treatment of Pain due to muscle spasm
Dotadic 250mg/50mg/325mg Tablet MR is a combination medicine that is used to relieve pain, inflammation, and swelling in conditions that affect muscles. Also, it effectively relieves muscle stiffness or spasm, thereby improving muscle movement. It works by blocking chemical messengers in the brain that tell us we have pain.
Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Dotadic Tablet MR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dotadic
Nausea
Vomiting
Heartburn
Stomach pain
Diarrhea
Loss of appetite
Dryness in mouth
Indigestion
Skin rash
How to use Dotadic Tablet MR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dotadic 250mg/50mg/325mg Tablet MR is to be taken with food.
How Dotadic Tablet MR works
Dotadic 250mg/50mg/325mg Tablet MR is a combination of a muscle relaxant (Chlorzoxazone) and two pain relieving medicines (Diclofenac and Paracetamol). The muscle relaxant works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm, thereby improving movement of muscles. The pain relieving medicines work by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling).
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Dotadic 250mg/50mg/325mg Tablet MR. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Dotadic 250mg/50mg/325mg Tablet MR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Dotadic 250mg/50mg/325mg Tablet MR during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Dotadic 250mg/50mg/325mg Tablet MR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Dotadic 250mg/50mg/325mg Tablet MR in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Dotadic 250mg/50mg/325mg Tablet MR in patients with liver disease. Please consult your doctor.
What if you forget to take Dotadic Tablet MR?
If you miss a dose of Dotadic 250mg/50mg/325mg Tablet MR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
sir/madam i have pain in my testical(in left side) it slept at 4am. when I woke up it was paining since 2 days it may be due to cold and there is no swelling. may be little bit.
Dr. Shyam Gupta
Obstetrics and Gynaecology
Hello PATIENT to 1mg. Your pain may be due to cold spasm or tortion. If pain persist please visit surgeon and examined.
When doing exercise got ache in the position of scapula L & spine. Take CALPOL T . But now I feel twinge at left arm as if vein is obstructed when I bent and move.
Dr. Rohit Chakor
Orthopaedics
Muscle spasm is the reason. Do Xray to rule out spine problem
I've got muscle spasm in back due to heavy weight lifting and this excruciating pain is unbearable . I'm unable to change my body posture or can't walk due to pain. I'm lying all the time and it just happened last night.
Dr. Mehtab Baig
Orthopaedic Physiotherapy
Plz you don't move your body and no any exercise done for fifteen days absolute bed rest
Dotadic 250mg/50mg/325mg Tablet MR is a combination of three medicines: Diclofenac, Paracetamol, and Chlorzoxazone. This medication helps in relieving muscle pain. Chlorzoxazone is a muscle relaxant which works by acting on the central nervous system. Diclofenac and Paracetamol work by lowering the chemical substance (prostaglandins) in the body that causes pain and inflammation.
Is it safe to use Dotadic 250mg/50mg/325mg Tablet MR?
Dotadic 250mg/50mg/325mg Tablet MR is safe for most of the patients. However, in some patients it may cause common side effects like nausea, vomiting, heartburn, stomach pain, diarrhea, loss of appetite, dryness in the mouth, weakness, sleepiness and other uncommon or rare side effects. Inform your doctor as soon as possible if you experience any persistent problem due to the medication.
Can I stop taking Dotadic 250mg/50mg/325mg Tablet MR when my pain is relieved?
Dotadic 250mg/50mg/325mg Tablet MR should be continued if advised for a specific time duration by your doctor. However, it can be discontinued if you are using it for short-term pain relief.
Can the use of Dotadic 250mg/50mg/325mg Tablet MR cause nausea and vomiting?
Yes, the use of Dotadic 250mg/50mg/325mg Tablet MR can cause nausea and vomiting. In case, you experience nausea while taking this medicine, take it with milk, food or with antacids. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Can the use of Dotadic 250mg/50mg/325mg Tablet MR cause dizziness?
Yes, the use of Dotadic 250mg/50mg/325mg Tablet MR can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better.
Can the use of Dotadic 250mg/50mg/325mg Tablet MR cause damage to kidneys?
Yes, the long-term use of Dotadic 250mg/50mg/325mg Tablet MR can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.
Can I take a higher than the recommended dose of this medicine?
No, taking a higher than the recommended dose of Dotadic 250mg/50mg/325mg Tablet MR can increase the risks of side effects. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
What are the recommended storage conditions for Dotadic 250mg/50mg/325mg Tablet MR?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
Federal Register. Determination That PARAFLEX (Chlorzoxazone) Tablets, 250 Milligrams, Was Not Withdrawn From Sale for Reasons of Safety or Effectiveness. 2013. [Accessed 16 Sep. 2024] (online) Available from: