Doxyril 25mg Tablet
Prescription Required
Product introduction
Doxyril 25mg Tablet is a tricyclic antidepressant. It is used in the treatment of insomnia (difficulty in sleeping). It is also used in patients intolerant of or unresponsive to alternative (other) treatment options for depression and anxiety disorders.
Doxyril 25mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is usually advised to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medicine.
The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure, especially when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chances of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.
Doxyril 25mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is usually advised to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medicine.
The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure, especially when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chances of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.
Uses of Doxyril Tablet
Benefits of Doxyril Tablet
In Treatment of Anxiety disorder
Doxyril 25mg Tablet reduces the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems that often come with Anxiety Disorder. It will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
Side effects of Doxyril Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Doxyril
- Increased heart rate
- Blurred vision
- Constipation
- Difficulty in urination
- Dryness in mouth
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Weight gain
How to use Doxyril Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Doxyril 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Doxyril Tablet works
Doxyril 25mg Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Doxyril 25mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Doxyril 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Doxyril 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
The baby should be monitored carefully for excessive sleepiness, and adequate weight gain.
The baby should be monitored carefully for excessive sleepiness, and adequate weight gain.
Driving
UNSAFE
Doxyril 25mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Doxyril 25mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Doxyril 25mg Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.
However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Doxyril 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Doxyril 25mg Tablet may be needed. Please consult your doctor.
What if you forget to take Doxyril Tablet?
If you miss a dose of Doxyril 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Doxyril 25mg Tablet helps in the treatment of insomnia, depression and anxiety.
- Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine.
- Inform your doctor if you notice a loss of consciousness, agitation, reduced breathing rate, convulsions, muscle rigidity, and mouth dryness.
- You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
- Do not drive or do anything that requires concentration until you know how the medicine affects you.
- Do not stop taking the medication suddenly without talking to your doctor.
- The main dose should be taken at night as this medicine may produce drowsiness or sleepiness.
- It can take 2 to 3 weeks for Doxyril 25mg Tablet to start working.
- You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
- If your doctor asks you to stop Doxyril 25mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
- Avoid driving or operating machinery as it may decrease alertness.
- Avoid consuming alcohol when taking the Doxyril 25mg Tablet, as it may cause excessive drowsiness and calmness.
- The addiction/dependence potential of Doxyril 25mg Tablet is very less.
- It may be extremely dangerous in overdose.
Fact Box
Chemical Class
Dibenzoxepin Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic Antidepressants (TCAs)
Interaction with drugs
Taking Doxyril with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause a fatal increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of co
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Domperidone with Doxepin.
Concurrent use may cause serotonin syndrome.
Careful consideration is advised if you have epilepsy. Watch out for symptoms of serotonin syndrome, such as sedation, respiratory imp
Concurrent use may cause serious disturbance in heart rhythm.
If concurrent use is essential, watch out for symptoms such as sleepiness, dry mouth, impaired voluntary movements, w
Patient concerns
FAQs
Can I stop taking Doxyril 25mg Tablet abruptly?
No, you should always check with your doctor before you stop taking Doxyril 25mg Tablet. Stopping the medicine abruptly may cause withdrawal effects. So, your doctor may reduce your dose gradually before taking you off the medicine completely. This helps to prevent a recurrence of the symptoms of depression and also reduces the chances of withdrawal symptoms.
Does Doxyril 25mg Tablet cause withdrawal symptoms?
Yes, stopping the use of Doxyril 25mg Tablet abruptly results in withdrawal symptoms which include insomnia (trouble falling asleep), irritability and excessive sweating. You should consult your doctor if you need to stop Doxyril 25mg Tablet. You doctor may gradually reduce the dose of Doxyril 25mg Tablet before taking you off Doxyril 25mg Tablet completely.
When must Doxyril 25mg Tablet not be taken?
You should not take Doxyril 25mg Tablet if you have ever had an allergic reaction to antidepressant medicines (such as Doxyril 25mg Tablet), or any of the inactive ingredients of Doxyril 25mg Tablet. Avoid taking Doxyril 25mg Tablet if you have glaucoma (increased eye pressure), liver problems, any difficulty in passing urine, if you are pregnant or breastfeeding. Do not take Doxyril 25mg Tablet if you are taking or have taken monoamine oxidase inhibitors (MAOIs) in the last two weeks or, if you suffer from mania (where you experience an abnormally elevated and excitable mood). It should not be given to children under 12 years of age.
Can I drive while on Doxyril 25mg Tablet treatment?
Taking Doxyril 25mg Tablet may cause sleepiness, so you should avoid driving or working with machinery until the effect has worn off. Driving while taking Doxyril 25mg Tablet may increase the risk of sleep-driving. This refers to driving while not fully awake after taking a sleeping medicine that can lead to decreased awareness of the surroundings and cause accidents.
What are the overdose symptoms of Doxyril 25mg Tablet?
Overdose of Doxyril 25mg Tablet can be mild or severe. Signs and symptoms of mild overdose include drowsiness, blurred vision and excessive dryness of the mouth. Severe overdose may cause loss of consciousness, difficulty breathing, convulsions, low blood pressure, unusually fast heartbeat or palpitations. If you take too much of Doxyril 25mg Tablet, contact your doctor immediately or seek emergency medical help.
How long does it take for Doxyril 25mg Tablet to kick in?
It may take several weeks or longer for you to experience significant benefits of Doxyril 25mg Tablet. Do not stop taking Doxyril 25mg Tablet without talking to your doctor, even if you feel better.
Can Doxyril 25mg Tablet treat insomnia?
Yes. Doxyril 25mg Tablet is also used for the treatment of insomnia (difficulty sleeping). It is especially helpful for people who have trouble staying asleep.
Can I drink alcohol while on treatment with Doxyril 25mg Tablet?
No, you should not drink alcohol while taking Doxyril 25mg Tablet as alcohol can increase the sleepiness or dizziness that occur as side effects of Doxyril 25mg Tablet.
Is Doxyril 25mg Tablet addictive?
Generally Doxyril 25mg Tablet does not cause dependence and is therefore not addictive. But, you should not stop taking Doxyril 25mg Tablet abruptly as it may cause temporary withdrawal symptoms such as insomnia (trouble falling asleep), irritability and excessive sweating.
Can Doxyril 25mg Tablet cause suicidal thoughts?
Yes, Doxyril 25mg Tablet can cause suicidal thoughts. This is more common in people who have previously had thoughts about killing or harming themselves, are younger than 25 years of age with a history of psychiatric conditions and who have earlier been treated with an antidepressant. If you experience suicidal thoughts, contact your doctor or go to a hospital straight away. You may also find it helpful to talk to a relative or close friend.
Does Doxyril 25mg Tablet cause weight gain or loss of appetite?
Doxyril 25mg Tablet may cause weight gain as well as loss of appetite, but it is not very common. Call your doctor if any of these bother you.
What is the best time to take Doxyril 25mg Tablet?
Doxyril 25mg Tablet should be taken in the dose and duration advised by the doctor. Your dose will depend on the illness you are being treated for. If you are taking Doxyril 25mg Tablet for insomnia, you should take it 30 minutes just before bedtime and you should not do anything that needs mental focus. If you are taking it for depression or anxiety, take it exactly as directed by your doctor. Remember to take this medicine at the same time each day to avoid missing doses.
What are the side effects of Doxyril 25mg Tablet?
The side effects of Doxyril 25mg Tablet include increased heart rate, weight gain, dryness in mouth, orthostatic hypotension (sudden lowering of blood pressure on standing), constipation and difficulty in urination. It may make your skin more sensitive to sunlight, cause chills and excessive sweating. Please consult your doctor if any of these side effects worry you or do not go away.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Doxepin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 211-17.
- Skidgel RA, Kaplan AP, Erdös EG. Histamine, Bradykinin, and Their Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 923.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 430-31.
- Doxepin. San Diego: Somaxon Pharmaceuticals; 1969 [revised date]. [Accessed 22 Mar. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
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