Drotal-M Tablet is a combination medicine used in the treatment of abdominal pain. It works effectively to reduce abdominal pain, bloating, discomfort and cramps by relaxing the muscles of the stomach and gut. It also blocks certain chemical messengers that cause pain and discomfort.
Drotal-M Tablet is taken with food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are diarrhea, nausea, vomiting, stomach pain, dryness in mouth, loss of appetite, feeling thirsty, and heartburn. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Drotal-M Tablet effectively relieves sudden muscle spasms or contractions in the stomach and intestine (gut), thereby relaxing the muscles and improving movement of food. It also blocks chemical messengers in the brain that are responsible for pain sensation. This helps to treat abdominal pain (or stomach pain) as well as cramps, bloating and discomfort. Take Drotal-M Tablet as prescribed by the doctor. Eventually, it will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Drotal-M Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Drotal-M
Nausea
Vomiting
Diarrhea
Dryness in mouth
Heartburn
Vertigo
Insomnia (difficulty in sleeping)
Hypotension (low blood pressure)
Fast heart rate
Sweating
Constipation
Increased liver enzymes
Increased white blood cell count (eosinophils)
Decreased white blood cell count (lymphocytes)
Breathlessness
Abdominal pain
Indigestion
Confusion
How to use Drotal-M Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Drotal-M Tablet is to be taken with food.
How Drotal-M Tablet works
Drotal-M Tablet is a combination of two medicines: Drotaverine and Mefenamic Acid, which relieves abdominal pain and cramps. Drotaverine is an anti-spasmodic medicine which relieves contractions (spasms) associated with smooth muscles in the abdomen. Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause abdominal pain and inflammation (swelling).
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Drotal-M Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Drotal-M Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Drotal-M Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Drotal-M Tablet may cause side effects which could affect your ability to drive. As Drotal-M Tablet may cause vertigo.
Kidney
CAUTION
Drotal-M Tablet should be used with caution in patients with kidney disease. Dose adjustment of Drotal-M Tablet may be needed. Please consult your doctor. Use of Drotal-M Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Drotal-M Tablet should be used with caution in patients with liver disease. Dose adjustment of Drotal-M Tablet may be needed. Please consult your doctor.
What if you forget to take Drotal-M Tablet?
If you miss a dose of Drotal-M Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
I have Allergic rhynitis for last 20 years. I am taking Rupanex M tablet every day for last 4 years. I am ok now and no cold and cough but feel tiredness most of time and body pain since last 2 years. Is it because of Rupanex M or by anything else. Please suggest. Should I continue taking Rupanex M. What are the side effects of this medicine for long time use
Dr. Pushkar Mani
Physician
Chest pain or tightness, Trouble breathing, Abdominal and stomach pain, Bloody nose, Unusual tiredness and weakness, Joint pain, Abdominal cramps, Excessive sweating, Allergic reactions such as shortness of breath, Abnormal increase in sweating, General feeling of discomfort or illness, Andheadache, Flu like symptomsYou should consult ENT good and u cant take medication for this long, it will damage ur immune system, and allergic rhinitis should be managed with other measures,, consult ENT
I have some serious back pain issue,for about 2 years now,sometimes it eases a bit but worsen more often. I feel the pain severely only after my afternoon sleep. Currently for around last one year having only zerodol th8 tablets to get some relief . Yet for last one week the pain is not easing even after having the tablet twice daily. Can you please help.
Dr. Mehtab Baig
Orthopaedic Physiotherapy
Stop zerodol tab. Do a m. R. I. First,M. R. I. Of whole spine
Burning sensation in sole ,penile region regularly No spot at penile area but constant burning sensation at sole and penile area No relief from amoxicillin,ceprofloxin doxycyclene Period :last 14 days
Dr. Pranay Gandhi
Sexology
that may be a neuropathic pain. do u have high bp or diabetes. take tablet pregama m 1 od for 15 days
Drotal-M Tablet is a combination of two medicines: Drotaverine and Mefenamic acid. This medication helps to relieve abdominal pain. Drotaverine relieves muscle spasms associated with smooth muscles in the abdomen. Mefenamic Acid works by blocking the release of certain chemical messengers that cause pain and inflammation (swelling).
Is it safe to use Drotal-M Tablet?
Yes, Drotal-M Tablet is safe for most of the patients with abdominal pain. However, in some patients it may cause common side effects like nausea, vomiting, heartburn, diarrhoea, loss of appetite, dryness in the mouth, weakness, sleepiness and other uncommon or rare side effects. If you experience any persistent problem while taking this medication, inform your doctor as soon as possible.
Can I stop taking Drotal-M Tablet when my pain is relieved?
Drotal-M Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Drotal-M Tablet should be continued if your physician has advised you to do so.
Can the use of Drotal-M Tablet cause nausea and vomiting?
Yes, the use of Drotal-M Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Also, avoid taking fatty or fried foods along with the medicine. Talk to your doctor if you have vomiting persists and you notice any signs of dehydration like less urination with dark coloured and strong-smelling urine. Do not take any other medicine without consulting your doctor.
Can the use of Drotal-M Tablet cause dry mouth?
Yes, the use of Drotal-M Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Avoid spicy, salty and acidic foods (like lemons).
Can I take a higher than the recommended dose of this medicine?
No, do not take a higher than the recommended dose of Drotal-M Tablet as it can increase the risks of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
What are the recommended storage conditions for Drotal-M Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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References
PubChem. Drotaverine. [Accessed 15 Apr. 2019] (online) Available from:
FDA approved prescribing information. Mefenamic Acid; 2008 [revised Mar. 2007]. [Accessed 15 Apr. 2019] (online) Available from:
MedIndia. Drotaverine - Indications, Dosage, Side Effects and Precautions. [Accessed 15 Apr. 2019] (online) Available from:
ScienceDirect. Mefenamic Acid. [Accessed 15 Apr. 2019] (online) Available from:
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.