Drotine MF 80mg/250mg Tablet is a combination medicine used in the treatment of abdominal pain. It works effectively to reduce abdominal pain, bloating, discomfort and cramps by relaxing the muscles of the stomach and gut. It also blocks certain chemical messengers that cause pain and discomfort.
Drotine MF 80mg/250mg Tablet is taken with food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are diarrhea, nausea, vomiting, stomach pain, dryness in mouth, loss of appetite, feeling thirsty, and heartburn. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Drotine MF 80mg/250mg Tablet effectively relieves sudden muscle spasms or contractions in the stomach and intestine (gut), thereby relaxing the muscles and improving movement of food. It also blocks chemical messengers in the brain that are responsible for pain sensation. This helps to treat abdominal pain (or stomach pain) as well as cramps, bloating and discomfort. Take Drotine MF 80mg/250mg Tablet as prescribed by the doctor. Eventually, it will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Drotine MF Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Drotine MF
Nausea
Vomiting
Diarrhea
Dryness in mouth
Heartburn
Vertigo
Insomnia (difficulty in sleeping)
Hypotension (low blood pressure)
Fast heart rate
Sweating
Constipation
Increased liver enzymes
Increased white blood cell count (eosinophils)
Decreased white blood cell count (lymphocytes)
Breathlessness
Abdominal pain
Indigestion
Confusion
How to use Drotine MF Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Drotine MF 80mg/250mg Tablet is to be taken with food.
How Drotine MF Tablet works
Drotine MF 80mg/250mg Tablet is a combination of two medicines: Drotaverine and Mefenamic Acid, which relieves abdominal pain and cramps. Drotaverine is an anti-spasmodic medicine which relieves contractions (spasms) associated with smooth muscles in the abdomen. Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause abdominal pain and inflammation (swelling).
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Drotine MF 80mg/250mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Drotine MF 80mg/250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Drotine MF 80mg/250mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Drotine MF 80mg/250mg Tablet may cause side effects which could affect your ability to drive. As Drotine MF 80mg/250mg Tablet may cause vertigo.
Kidney
CAUTION
Drotine MF 80mg/250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Drotine MF 80mg/250mg Tablet may be needed. Please consult your doctor. Use of Drotine MF 80mg/250mg Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Drotine MF 80mg/250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Drotine MF 80mg/250mg Tablet may be needed. Please consult your doctor.
What if you forget to take Drotine MF Tablet?
If you miss a dose of Drotine MF 80mg/250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Hello , sir since this past december i am facing problems like headache ,eye pain , weakness and sometimes abdominal pain .i want to tell you that 7 months ago i joined gym and i started to eat 25 chapatis and 100 gms of roasted peanuts daily to gain weight and i also ate used protien powder for about a month so i cannot figure out which thing caused illness or i am just depressed
Dr. Sunil Sekhri
Diabetology
Abdominal pain could be because of excess diet. Other symptoms are non specific.
Excessive naussea during pregnancy (last period 19th august) and 1-2 vomit per day. Pain in middle of upper abdomen what to do to subside naussea and vomit for abdomen pain DIOVOL Forte plus syrup can be given?
Dr. Suman Rao
Obstetrics and Gynaecology
Take antacid for abdominal pain. Med can be taken for vomiting. Consult your Gynae
I'm having stomach pain since the last few weeks. I also went to the doctor for a checkup and was diagnosed with enteritis and was given medication for some few days. I was fine then but after a week pain has started again. Please tell the right medication
Dr. Sfurti Mann
Internal Medicine
get ultrasound abdomen, LKT, KFT, amylase, lipase done to know the cause of pain. take tab meftal forte for abdominal spasmodic pain.
Drotine MF 80mg/250mg Tablet is a combination of two medicines: Drotaverine and Mefenamic acid. This medication helps to relieve abdominal pain. Drotaverine relieves muscle spasms associated with smooth muscles in the abdomen. Mefenamic Acid works by blocking the release of certain chemical messengers that cause pain and inflammation (swelling).
Is it safe to use Drotine MF 80mg/250mg Tablet?
Yes, Drotine MF 80mg/250mg Tablet is safe for most of the patients with abdominal pain. However, in some patients it may cause common side effects like nausea, vomiting, heartburn, diarrhoea, loss of appetite, dryness in the mouth, weakness, sleepiness and other uncommon or rare side effects. If you experience any persistent problem while taking this medication, inform your doctor as soon as possible.
Can I stop taking Drotine MF 80mg/250mg Tablet when my pain is relieved?
Drotine MF 80mg/250mg Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Drotine MF 80mg/250mg Tablet should be continued if your physician has advised you to do so.
Can the use of Drotine MF 80mg/250mg Tablet cause nausea and vomiting?
Yes, the use of Drotine MF 80mg/250mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Also, avoid taking fatty or fried foods along with the medicine. Talk to your doctor if you have vomiting persists and you notice any signs of dehydration like less urination with dark coloured and strong-smelling urine. Do not take any other medicine without consulting your doctor.
Can the use of Drotine MF 80mg/250mg Tablet cause dry mouth?
Yes, the use of Drotine MF 80mg/250mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Avoid spicy, salty and acidic foods (like lemons).
Can I take a higher than the recommended dose of this medicine?
No, do not take a higher than the recommended dose of Drotine MF 80mg/250mg Tablet as it can increase the risks of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
What are the recommended storage conditions for Drotine MF 80mg/250mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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References
PubChem. Drotaverine. [Accessed 15 Apr. 2019] (online) Available from:
FDA approved prescribing information. Mefenamic Acid; 2008 [revised Mar. 2007]. [Accessed 15 Apr. 2019] (online) Available from:
MedIndia. Drotaverine - Indications, Dosage, Side Effects and Precautions. [Accessed 15 Apr. 2019] (online) Available from:
ScienceDirect. Mefenamic Acid. [Accessed 15 Apr. 2019] (online) Available from:
PACE Hospital. Drotaverine Hydrochloride: Uses, Dose, Side Effects, Indications and Cost. [Accessed 16 Sep. 2024] (online) Available from:
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