Dulodep 10mg Tablet is used in the treatment of depression, anxiety disorder, diabetic nerve pain, fibromyalgia (a condition in which there are generalized pain and tenderness in the body), neuropathic pain, and stress urinary incontinence.
Dulodep 10mg Tablet works by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that have a calming effect on the brain and relax the nerves, thus treating your illness. It may be taken with or without food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly as it may worsen your symptoms.
Some common side effects of this medicine include nausea, headache, decreased libido, abnormal dreams, blurred vision, and dry mouth. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or bother you.
Before taking Dulodep 10mg Tablet, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts.
Stress urinary incontinence refers to the loss of urine without conscious intention. It may occur due to a disturbed state of mind and thoughts. Dulodep 10mg Tablet helps in increasing the activity of those nerves in the brain that control muscles in our bladder that are responsible for passing urine. This helps in improving bladder control.
Side effects of Dulodep Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dulodep
Nausea
Headache
Dryness in mouth
Sleepiness
Dizziness
Blurred vision
Decreased libido
Abnormal dreams
How to use Dulodep Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dulodep 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Dulodep Tablet works
Dulodep 10mg Tablet works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Dulodep 10mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Dulodep 10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Dulodep 10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Dulodep 10mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Dulodep 10mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Dulodep 10mg Tablet may be needed. Please consult your doctor.
Liver
UNSAFE
Dulodep 10mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
What if you forget to take Dulodep Tablet?
If you miss a dose of Dulodep 10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More
Concurrent use may cause serotonin syndrome.
If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult... More
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
What are possible physical symptoms of anxiety disorder and depression.
Dr. Subrata Naskar
Psychiatry
Hi PATIENT me clear that for you. Depression is usually associated with a lot of physical symptoms like increased fatigue, decreased amount of sleep or interrupted sleep, loss of appetite usually cause more than 5% body weight loss, loss of libido. But its effect is mainly psychological whivh causes persist low mood, inability to enjoy pleasurable activities, low self esteem, bleak view of the future, guilty feeling etc. These symptoms have to be present persistently for 2 weeks to be called depression. On the other hand, anxiety has two main components, worry and fear. The common physical complaints are extreme sweating, butterfly like feeling in stomach, fidgetiness, increased frequency of urination. If associated with panic attacks, there is often palpitation, respiratory distress, dryness of throat, a sense of doom. Anxiety disorders are of various types and each have varied specific set of symptoms, but these are usually in common.
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Endogenous depression occurs without any noticeable environmental stressors.Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it's an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. If the condition is persisting for a long time, it's better to see a psychiatrist.
how to tackle depression and post traumal stress disorder?
Dr. Jyoti Kapoor Madan
Psychiatry
Psychiatric evaluation is based on history, clinical symptoms, personality factors, ongoing psychosocial stressors and frequency and severity of symptoms. It requires direct interaction with the patient on a regular basis. Once diagnosed, a management plan is formed based on intensity and frequency of symptoms and associated biological and psycho social factors. A complete solution to ones problems in a single question is thus not possible. Internet will give you generalised tips and tricks but they are hardly of any use. I suggest you to visit a psychiatrist in your vicinity for clinical evaluation.
In people with depression and anxiety, Dulodep 10mg Tablet mostly starts working within two weeks of treatment. However, you may take 2-4 weeks to feel better. Consult your doctor if you do not see any improvement after this time. In people with diabetic neuropathic pain, you may take a few weeks to feel better. Consult your doctor if you do not feel better after 2 months.
If I start feeling better, can I stop taking Dulodep 10mg Tablet?
No, you should not stop Dulodep 10mg Tablet suddenly and without consulting your doctor. In cases of depression and anxiety, if you have been feeling better for 6 months or more, your doctor may reduce your doses gradually. In case of pain and incontinence, if you are feeling better, continue taking it for the long term. Your doctor will keep monitoring your response to the medicine every few months.
Is Dulodep 10mg Tablet highly addictive?
No, Dulodep 10mg Tablet is not habit-forming (addictive). This means that it does not make you physically or psychologically dependent on it.
What will be the consequences if I stop taking Dulodep 10mg Tablet suddenly?
If you stop Dulodep 10mg Tablet suddenly, you may feel dizzy, tired, agitated or restless, anxious and irritated. You may also experience sleep disturbances (vivid dreams, nightmares, inability to sleep), nausea, vomiting, shaking, muscle pain, diarrhea, a piercing sensation (pins and needles) especially in the head, and excessive sweating or vertigo. Always consult your doctor before you stop taking Dulodep 10mg Tablet. Your doctor will reduce the dose gradually.
I am taking warfarin, does Dulodep 10mg Tablet interfere with warfarin? Is it safe to take both together?
You should be cautious if you are taking both Dulodep 10mg Tablet and warfarin since there is a risk of bleeding or you may experience petechiae or purpura.
Is Dulodep 10mg Tablet safe to use for long term?
Dulodep 10mg Tablet is safe to use for a long duration, provided you follow your doctor’s advice regarding the treatment.
I am a hypertensive patient. I have noticed that my blood pressure has increased after I started taking Dulodep 10mg Tablet. Is it because of Dulodep 10mg Tablet, what should be done?
Dulodep 10mg Tablet may cause an increase in blood pressure. Therefore, regular monitoring of blood pressure is required, especially during the first month of use. If your blood pressure increase is constant, consult your doctor. It may indicate that your Dulodep 10mg Tablet dose either needs to be reduced or discontinued gradually.
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References
Stahl SM, editor. Duloxetine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 219-24.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 442-43.
Duloxetine hydrochloride. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 09 Nov. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Duloxetine. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Duloxetine Gastro-Resistant Tablets [Patient Information Sheet]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2022. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: East West Pharma
Address: No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.