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Written By
MDS (Oral Pathology & Microbiology), BDS
Reviewed By
MBA, MD Pharmacology
Last updated
12 Nov 2024 | 01:05 AM (IST)

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Duphalac Oral Solution

Marketer
SALT COMPOSITION
Storage
Store below 30°C
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Product introduction

Duphalac Oral Solution is a type of sugar used to treat constipation. It is known as a laxative and makes your stool easier to pass by drawing water into your bowel. It is also used to treat hepatic encephalopathy (a liver disease causing confusion, tremor, decreased level of consciousness).

Duphalac Oral Solution can be taken with or without food. You should take this medicine as advised by your doctor. Use this medicine regularly to get the maximum benefit and try to take it at the same time(s) each day. Your dose may go up or down depending on how well it is working. Do not take more than you are advised to and, if you miss a dose, do not take an extra one to make up for it. This medicine takes at least 48 hours to work. Talk to your doctor if you are still constipated after 3 days.

The most common side effects are nausea and vomiting. These are usually mild and go away after a couple of days. Occasionally people develop serious side effects including severe diarrhea and electrolyte imbalance. Talk to your doctor straight away if you notice any of these.

Before taking this medicine, you should tell your doctor if you have diabetes or if you are unable to digest milk sugar (lactose intolerant). If you use this medicine over a long period of time, your doctor may want you to have occasional blood tests to check the mineral levels (e.g. potassium and sodium). Do not take other laxative medicines while taking this medicine and check with your doctor if you are pregnant or breastfeeding.

Uses of Duphalac Oral Solution

  • Constipation
  • Intestine preparation before any surgery
  • Treatment of Hepatic encephalopathy

Benefits of Duphalac Oral Solution

In Treatment of Hepatic encephalopathy

Hepatic encephalopathy is a severe liver disease that can cause changes in brain function leading to confusion, tremors (shaking), sleep problems, and loss of consciousness. Duphalac Oral Solution is thought to work by lowering the level of a substance called ammonia in the blood which has harmful effects on the brain. If taken as prescribed, it can improve your brain function and reduce symptoms associated with hepatic encephalopathy.

Side effects of Duphalac Oral Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Duphalac

  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea

How to use Duphalac Oral Solution

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Duphalac Oral Solution may be taken with or without food, but it is better to take it at a fixed time.

How Duphalac Oral Solution works

Duphalac Oral Solution works by drawing water into the intestine through osmosis, which makes the stool soft and easier to pass.

Safety advice

Alcohol
SAFE
Consuming alcohol with Duphalac Oral Solution does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Duphalac Oral Solution is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Duphalac Oral Solution is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Duphalac Oral Solution does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Duphalac Oral Solution is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Duphalac Oral Solution may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Duphalac Oral Solution is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Duphalac Oral Solution may not be needed in these patients. Please consult your doctor.

What if you forget to take Duphalac Oral Solution?

If you miss a dose of Duphalac Oral Solution, skip it and continue with your normal schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Duphalac Oral Solution
₹171.67/Oral Solution
Laxit L Oral Solution
Duckbill Drugs Pvt Ltd
₹258/oral solution
50% costlier
Esivac Oral Solution
Intas Pharmaceuticals Ltd
₹210/oral solution
22% costlier
Lacturite Oral Solution
MHS Pharmaceuticals Pvt Ltd
₹150/oral solution
13% cheaper
₹115/oral solution
33% cheaper
Esivac Oral Solution
Intas Pharmaceuticals Ltd
₹117/oral solution
32% cheaper

Quick tips

  • Duphalac Oral Solution is used in the treatment of constipation and hepatic encephalopathy.
  • It should preferably be taken at bedtime as it requires 6 to 8 hours to show effect.
  • It is usually taken once a day as needed for up to 2 weeks. Take it exactly as prescribed by the doctor.
  • Take it atleast 2 hours after taking other medicines, as it may interfere with the absorption of other medicines.
  • Inform your doctor if you have a history of stomach disorders such as appendicitis or a blockage in your bowel.
  • Some healthy tips to prevent constipation from happening:
    • Eat more fiber in your diet. Recommended daily intake is 20-35g
    • Drink 8-10 glasses of water per day
    • Exercise regularly at least 3 times per week
    • Do not hold in stool as that can worsen bowel issues
  • Duphalac Oral Solution is used for the treatment of constipation.
  • Some healthy tips to prevent constipation from happening:
    • Eat more fiber in your diet. Recommended daily intake is 20-35g
    • Drink 8-10 glasses of water per day
    • Exercise regularly at least 3 times per week
    • Do not hold in stool as that can worsen bowel issues
  • Take it atleast 2 hours after taking other medicines, as it may interfere with the absorption of other medicines.
  • It should preferably be taken at bedtime as it requires 6 to 8 hours to show effect.
  • It is usually taken once a day as needed for up to 2 weeks. Take it exactly as prescribed by the doctor.
  • Inform your doctor if you have a history of stomach disorders such as appendicitis or a blockage in your bowel.

Fact Box

Chemical Class
Synthetic Disaccharide
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Osmotic Laxatives / Purgatives

Patient concerns

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Do the Gutclear syrup n duphalac oral solution both are same or has same effect? Which is better?
Dr. Pushkar Mani
Physician
both are same and effective u can take any onw u want
I have a constipation problems. My stomach does not secrete proper digestive enzymes. In my large intestine walls there are so many bad excrete materials suck. Please eeeee suggest me what can i do?
Dr. Pushkar Mani
Physician
syrup DUPHALAC 15ml in night for 2 week
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User feedback


FAQs

Q. How long does it take for Duphalac Oral Solution to work?

It takes about 2-3 days to see the benefits of the treatment. Talk to your doctor if you feel constipated even after 3 days of taking Duphalac Oral Solution.

Q. What is Duphalac Oral Solution used for?

Duphalac Oral Solution is used to treat constipation which is presented as infrequent bowel movements, hard and dry stools. It is also used in patients with hepatic encephalopathy which is a serious liver problem causing confusion, tremors and decreased level of consciousness.

Q. Is Duphalac Oral Solution a laxative?

Yes, Duphalac Oral Solution is a laxative which softens the stools by pulling in water from the body to the large intestine. It is also used to reduce the amount of ammonia in the blood of patients with liver disease.

Q. What are the side effects of taking Duphalac Oral Solution?

Duphalac Oral Solution very commonly causes diarrhea, flatulence, nausea, vomiting and abdominal pain. Diarrhea and abdominal pain occur due to a high dose. In such cases, the dose should be reduced. Flatulence may occur during the first few days of treatment and may disappear after sometime. This medicine may also cause electrolyte imbalance. However, this is an uncommon side effect.

Q. Is it okay to take Duphalac Oral Solution every day?

You should take Duphalac Oral Solution for as long as advised by your doctor. You may also take it for as long as constipation lasts, which may be up to a week. For hepatic encephalopathy, the treatment may be longer, even several months.

Q. Who should not be given Duphalac Oral Solution?

Duphalac Oral Solution should not be given to patients who are allergic to it or are intolerant to lactose (cannot process lactose). It should also be avoided in patients having galactosemia, a rare health problem where the body cannot process galactose.

Q. Can I take other laxatives along with Duphalac Oral Solution?

Usually, one laxative is sufficient to relieve constipation. In case you need more, your doctor may advise you to take one more laxative along with Duphalac Oral Solution. The risk of side effects is more with two laxatives.

Q. What if I take more than the recommended dose of Duphalac Oral Solution?

Taking more than the recommended dose of Duphalac Oral Solution may cause abdominal pain, electrolyte imbalance and diarrhea, which may last for a couple of days.

Q. How should Duphalac Oral Solution be taken?

You should take the prescribed amount in the measuring cup or spoon that is provided with the medicine. You can take it with water or fruit juice if you find it very sweet. Drink plenty of water for better results. Swallow it as soon as you keep it in mouth to prevent tooth decay which can occur if you take it for a longer time.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1332.
  2. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1079.
  3. Lactulose. Maidenhead, Berkshire: Intrapharm Laboratories Limited; 2015 [revised 12 Jan. 2017]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  4. Drugs.com. Lactulose. [Accessed 27 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Country of origin: India

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