E 2 Gel
Prescription Required
Product introduction
E 2 Gel is a female sex hormone (estrogen). This is a type of hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness, and itching); estrogen deficiency; and thinning of bones (osteoporosis).
In some cases, E 2 Gel is also used to treat breast cancer and prostate cancer along with other anticancer medicines. It is to be taken at a fixed time(s) daily. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.
The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, nausea, vomiting, and hair loss. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
In some cases, E 2 Gel is also used to treat breast cancer and prostate cancer along with other anticancer medicines. It is to be taken at a fixed time(s) daily. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.
The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, nausea, vomiting, and hair loss. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
Uses of E 2 Vaginal gel
Side effects of E 2 Vaginal gel
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of E 2
- Breast pain
- Breast enlargement
- Hair loss
- Uterine bleeding
- Depression
- Joint pain
- Leg cramps
- Leukorrhea
- Urinary tract infection
- Itching
- Irritable bladder
How to use E 2 Vaginal gel
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying
How E 2 Vaginal gel works
E 2 Gel is an estrogen (female sex hormone). In women who are undergoing or have attained menopause, it prevents symptoms such as hot flushes, night sweats and mood swings. It also prevents the bones from becoming porous and fragile (osteoporosis).
Safety advice
Alcohol
No interaction found/established
Pregnancy
UNSAFE
E 2 Gel is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
E 2 Gel is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- You have been prescribed E 2 Gel as a part of hormone replacement therapy to relieve symptoms of menopause.
- It may also be used for preventing osteoporosis in postmenopausal women who are at high risk of fractures.
- Take it at the same time everyday to help you remember to take it.
- Inform your doctor if you experience any unusual vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while taking E 2 Gel.
- It may increase the risk of breast cancer. Have regular breast examinations.
- Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, or changes in vision. These could be symptoms of a blood clot in a vein.
Fact Box
Chemical Class
Estradiol Congeners
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Estrogens
Patient concerns
User feedback
Patients taking E 2 Gel
Once A Day
83%
Thrice A Day
17%
FAQs
What is E 2 Gel and what is it used for?
E 2 Gel is an estrogen hormone. It helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness in women. It is also used to prevent osteoporosis (thinning and weakening of bones) in postmenopausal women, who are at high risk of fractures and have limited treatment choice.
When and how to take E 2 Gel?
Take E 2 Gel as per your doctor's advice. However, you must try to take E 2 Gel at the same time of each day, to ensure the consistent levels of medicine in your body.
What if I miss a dose of E 2 Gel?
If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule.
What are the most common side effects which I may experience while taking E 2 Gel?
The common side effects associated with E 2 Gel are lower abdominal pain, periods pain, breast tenderness, endometrial hyperplasia (thickening of uterus lining) and vaginal discharge. Most of these symptoms are temporary. However, if these persist, check with your doctor as soon as possible.
What can I take for estrogen deficiency?
For estrogen deficiency, treatment is based on the underlying cause. Your doctor may choose from a variety of medications depending upon whether your are young or old or have had your menopause. The medications will also depend upon whether you are estrogen deficient or have high progesterone levels, etc. You may be given bio-identical estradiol or estriol or counterbalance with natural progesterone.
Who should not take E 2 Gel?
E 2 Gel should not be taken by patients who have unusual vaginal bleeding, liver problems, or bleeding disorder. It should also be avoided to patients who are pregnant or are allergic to E 2 Gel. Patients who have had uterus or breast cancer, had a stroke or heart attack, or currently have or had blood clots should also avoid this medicine.
What are the serious side effects of E 2 Gel?
Serious side effects of E 2 Gel are uncommon and do not affect everyone. These serious side effects may include breast cancer, ovarian cancer, uterus cancer, stroke, heart attack, blood clots, gallbladder disease and dementia.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1173-75.
- Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 701-702.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 500-501.
- MedIndia. Estradiol. [Accessed 03 Apr. 2019] (online) Available from:
- Estradiol. Rockaway, New Jersey: Warner Chilcot; 2009. [Accessed 03 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 01 Apr. 2019] (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
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