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PGDHHM, BDS
Reviewed By
MD Pharmacology, MBBS
Last updated
22 Jan 2026 | 03:53 PM (IST)

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EMPRogest 8% Vaginal gel

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Storage
Store below 25°C

Product introduction

EMPRogest 8% Vaginal gel is prescribed to prevent miscarriage in women who experience vaginal bleeding in the first trimester and have a history of recurrent miscarriages. It supports early pregnancy by maintaining the uterine lining and creating a stable environment for the developing embryo.

EMPRogest 8% Vaginal gel should be inserted deep into the vagina exactly as prescribed. Use the medicine regularly and at the same time each day to maintain consistent support during early pregnancy. Treatment should always be guided by a doctor, and any ongoing bleeding or new symptoms should be reported promptly, as further evaluation may be required.


Most women tolerate EMPRogest 8% Vaginal gel well. Rarely, local side effects such as mild vaginal irritation, itching, burning sensation, or oily discharge may occur. These effects are usually mild and short-lived. If symptoms become bothersome or persistent, consult your doctor.


EMPRogest 8% Vaginal gel should be used only during the first trimester for the prevention of miscarriage. Any vaginal bleeding should always be investigated before and during treatment. The medicine should not be used in women with undiagnosed vaginal bleeding, severe liver disease, hormone-dependent cancers, thromboembolic disorders, or known allergy to progesterone or any ingredient in the product.


Uses of EMPRogest Vaginal gel

  • Prevention of Miscarriage

Benefits of EMPRogest Vaginal gel

In Prevention of Miscarriage

EMPRogest 8% Vaginal gel helps in the prevention of miscarriage, especially in women who experience bleeding in early pregnancy and have a history of recurrent pregnancy loss. It supports the pregnancy by maintaining the uterine lining, helping the womb stay relaxed, and creating a favourable environment for the developing embryo. Vaginal administration delivers progesterone directly to the uterus, ensuring effective local action with lower exposure to the rest of the body. This helps improve the chances of continuing the pregnancy and provides reassurance and stability during a critical early phase of pregnancy.

Side effects of EMPRogest Vaginal gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of EMPRogest

  • No common side effects seen

How to use EMPRogest Vaginal gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying

How EMPRogest Vaginal gel works

EMPRogest 8% Vaginal gel supports early pregnancy by acting on the uterus to maintain a healthy uterine lining needed for pregnancy to continue. It helps relax the uterine muscles, improves blood flow between the uterus and placenta, and reduces inflammatory and immune responses that could threaten the pregnancy.

Safety advice

Alcohol
No interaction found/established
Pregnancy
SAFE IF PRESCRIBED
EMPRogest 8% Vaginal gel is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
UNSAFE
EMPRogest 8% Vaginal gel is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

What if you forget to take EMPRogest Vaginal gel?

If you miss a dose of EMPRogest 8% Vaginal gel, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
EMPRogest 8% Vaginal gel
₹245/Vaginal gel
₹208.83/vaginal gel
23% cheaper
SustEN 8% Gel
Sun Pharmaceutical Industries Ltd
₹171.56/vaginal gel
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₹205.8/vaginal gel
24% cheaper
GEStone 8% Vaginal gel
Ferring Pharmaceuticals
₹182.82/vaginal gel
33% cheaper

Quick tips

  • Insert EMPRogest 8% Vaginal gel deep into the vagina while lying down, preferably at bedtime, to reduce leakage and help the medicine stay in place longer.
  • Use the medicine at regular times every day to maintain consistent hormonal support during early pregnancy.
  • Avoid skipping doses, especially during the first trimester, as this is a crucial period for supporting pregnancy.
  • Inform your doctor immediately if vaginal bleeding increases, becomes painful, or is accompanied by cramps or fever.
  • Avoid using other vaginal products such as douches, creams, or pessaries unless specifically prescribed, as they may interfere with treatment.

Fact Box

Chemical Class
Gluco/mineralocorticoids, progestogin derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Natural Progesterone

Interaction with drugs

Taking EMPRogest with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observat... More
Avoid concurrent use. Please consult with your doctor. Progesterone (Natural Micronized) is not recommended in individuals with known, suspected, or history of breast cancer. Prog... More
Avoid concurrent use. Please consult with your doctor. Progesterone (Natural Micronized) is not recommended for individuals who have or had breast cancer.
Avoid concurrent use. Please consult with your doctor. Progesterone (Natural Micronized) is not recommended for individuals who have or had breast cancer.
Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. It is recommended to consult your doctor. Mycophenolate mofetil ... More

Patient concerns

Doctor says pregnant but sac not healty The pregnancy alive or miscarage
Dr. Suman Rao
Obstetrics and Gynaecology
It's a miscarriage
I CONSULT THE DOCTOR INFERTILITY ,HE DID ALL TYPE OF TESTS AND SAID NO PROBLEMS IN OUR PARTNERS.HE GAVE ME MEDICINE SIPHENE,ARGITAS,EVADIOL,SIO CARE,EMPROGEST,IN THAT MONTH I GOT PREGNANCY BUT IT WAS ABORTED ON 1 MONTH 25 DAYS,IN LAST 8 MONTHS I USED THE MEDICINES BUT I DID NOT GET PREGNANCY,I DONT KNOW WHAT IS THE PROBLEM.IN LAST MONTH I ALSO DONE IUI TREATMENT ALSO BUT IT WAS ALSO FAIL.NOW I DONT KNOW WHAT I DO,EITHER I CONTINUE THE MEDICINES OR NOT.PLEASE GIVE A SUGGESTION WHAT I DO.
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
U can go for more iui cycles Have patience Don't worry

User feedback


FAQs

Who should use EMPRogest 8% Vaginal gel to prevent miscarriage?

EMPRogest 8% Vaginal gel is prescribed for women who experience bleeding in early pregnancy and have a history of recurrent miscarriages. It is not intended for routine use in all pregnancies and should only be taken when advised by a doctor.

When should I start using EMPRogest 8% Vaginal gel in pregnancy?

Treatment is usually started in the first trimester, often at the first sign of vaginal bleeding, and continued up to the 16th week of pregnancy, depending on medical advice.

How does EMPRogest 8% Vaginal gel help in preventing miscarriage?

EMPRogest 8% Vaginal gel helps maintain the uterine lining, keeps the uterus relaxed, and supports a stable environment for the developing embryo. Vaginal use allows the hormone to act directly on the uterus with lower exposure to the rest of the body.

Is vaginal discharge normal while using EMPRogest 8% Vaginal gel?

Yes. A mild oily or whitish vaginal discharge is common with EMPRogest 8% Vaginal gel and usually does not mean the medicine is not working. A panty liner may be used for comfort.

Can I stop EMPRogest 8% Vaginal gel once bleeding stops?

No. You should not stop the medicine on your own, even if bleeding improves. EMPRogest 8% Vaginal gel should be continued for the recommended duration to provide ongoing pregnancy support. Always follow your doctor’s advice before stopping.

Can EMPRogest 8% Vaginal gel prevent all miscarriages?

EMPRogest 8% Vaginal gel does not prevent all miscarriages. It is helpful in specific situations, particularly in women with early pregnancy bleeding and previous miscarriages. Some miscarriages may occur due to causes that this medicine cannot correct.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
  2. Progesterone [Prescribing Information]. North Chicago, IL: AbbVie Inc.; 2024. [Accessed 22 Jan. 2026] (online) Available from: External Link
  3. Progesterone [Summary of Product Characteristics]. Dublin, Ireland: Besins Healthcare Ireland Limited; 2024. [Accessed 22 Jan. 2016] (online) Available from: External Link

Marketer details

Name: Emcure Pharmaceuticals Ltd
Address: 255/2, Hinjawadi, Pune - 411057, India / Godown A, Gat No. 408 and 410, Vill: Urse, Tal: Maval, Pune-410 506, Maharashtra, India.
Country of origin: India
Expires on or after: October, 2026

A licensed vendor partner from your nearest location will deliver EMPRogest 8% Vaginal gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP272.4  10% OFF
245
Inclusive of all taxes
The price displayed is the MRP (inclusive of applicable taxes). Any additional fee (such as shipping fee, handling and/or platform fee etc.) will be clearly disclosed before you complete your purchase.
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