Product introduction
Eparel 50 Tablet is used to treat diabetic nerve pain. Poorly controlled diabetes can eventually lead to diabetic nerve disease (neuropathy) as a complication. This medicine helps to relieve symptoms like burning pain and numbness seen in people with diabetic nerve disease.
Eparel 50 Tablet belongs to a group of medicines known as Aldose reductase inhibitors. It can be taken with or without food but you should try to take it at the same time every day. This will help you to remember to take it. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. It may take up to 3 months to get the full benefits of this medicine, but you should keep taking it regularly. Do not stop taking it without asking your doctor, otherwise, your condition may worsen.
This medicine is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. You should also continue taking other medicines prescribed by your doctor for blood sugar control. Keeping your blood sugar levels under control will help this medication work better.
The most common side effects of this medicine include nausea, vomiting, and abnormalities in liver function tests (increased liver enzymes). Most side effects are temporary and improve as your body gets used to the medicine. Please consult your doctor if any of these bother you or do not go away.
Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Avoid any alcohol intake while taking it as this may increase the risk of developing some side effects.
Side effects of Eparel Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Eparel
- Nausea
- Vomiting
- Abnormal liver function
How to use Eparel Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Eparel 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Eparel Tablet works
Eparel 50 Tablet is an aldose reductase inhibitor. It blocks the accumulation of sorbitol in cells, which has been related to causing diabetic nerve disease.
Safety advice
It is unsafe to consume alcohol with Eparel 50 Tablet.
PregnancyCONSULT YOUR DOCTOR
Information regarding the use of Eparel 50 Tablet during pregnancy is not available. Please consult your doctor.
Breast feedingCONSULT YOUR DOCTOR
Information regarding the use of Eparel 50 Tablet during breastfeeding is not available. Please consult your doctor.
DrivingCONSULT YOUR DOCTOR
It is not known whether Eparel 50 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
KidneyCONSULT YOUR DOCTOR
There is limited information available on the use of Eparel 50 Tablet in patients with kidney disease. Please consult your doctor.
There is limited information available on the use of Eparel 50 Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take Eparel Tablet?
If you miss a dose of Eparel 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Eparel 50 Tablet
₹6.25/Tablet
₹18.1/tablet
190% costlier
Fact Box
Chemical Class
Carboxylic acid Derivative
Therapeutic Class
ANTI DIABETIC
Action Class
Aldose Reductase Inhibitors (ARIs)
Patient concerns
Diabetic patients nerve related pain treatment
Dr. Sanjay Bhatt
Physician
Write duration of diabetes
My father age is 50.he is diabetic.latest hba1c is 6.8 .he feels some strech(light pain in nerves) in stomach nerves when he stands or while walking.this problem is from long time(7-8 mnts old).he is fine when lie down.all the abdomen reports ct scan and ultrasound are all clear. latest results of esr(28) , and D3(29.4) can u suggest what the problem can be?if u find any problem in these reports plz provide the remedy.thanks in advance.
Dr. Vikas Sharma
Neurology
Cud be diabetic neuropathy Get nerve conduction done
I am a diabetic patient and having pain around and above ankle. It feel like stretch in nerve.
Dr. Vikas Sharma
Neurology
get nerve conduction done
Ostioarthraitis and nerve pain
Dr. Akshat Goel
Orthopaedics
Do Hot Fomentation and apply Dynapar QPS spray and take Tab Zerodol-SP twice daily and Cap Nurokind-Gold twice daily for 5 days
Severe sciatic nerve pain in from back to feet in one nerve
Dr. Akshat Goel
Orthopaedics
Take rest get a MRI done of LS spine Till then Take Tab Myospas-D thrice daily and Tab Flotrip-forte thrice daily and Tab Meganeuron-PG twice daily for 5 days
Occasion pain under feet just like some nervous issues. Some times nerve pain on leg parts below knee area. Is it diabetic related? Family history has diabetes
Dr. Vikas Sharma
Neurology
cud be; get nerve conduction done
What's is sciatica pain and its treatment options
Dr. M. K. Ansari
Neurology
sciatica pain is pan originating in scciatic nerve. a main nerve running from your buttocks and lower back upto the foot posteriorly. treatment of sciatica pain depends upon the cause of sciatic nerve involvement. Most of the time it is prolapsed intervertebral discs at lumbar region. and treatment involves medications to sooth the nerves nerve tonics and in some cases surgical removal of the compressive pathology
L2s1 leg pain nerve compression
Kindly consult a spine surgeon
User feedback
Patients taking Eparel 50 Tablet What are you using Eparel Tablet for?*Diabetic nerve pain
How much was the improvement? What were the side-effects while using Eparel 50 Tablet?*Abnormal liver function
How do you take Eparel Tablet? Please rate Eparel 50 Tablet on price
Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
Ramirez MA, Borja NL. Epalrestat: An aldose reductase inhibitor for the treatment of diabetic neuropathy. Pharmacotherapy. 2008;28(5):646-55. [Accessed 18 Mar. 2019] (online) Available from:
Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44. [Accessed 27 Mar. 2017] (online) Available from:
MIMS, Malaysia. Epalrestat. [Accessed 25 Jul. 2024] (online) Available from:
Marketer details
Name: Micro Labs Ltd
Address: 27, RACE COURSE ROAD, BANGALORE-560 001, INDIA
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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