Esoneu-D Capsule SR is a prescription medicine used to treat gastroesophageal reflux disease (Acid reflux) and indigestion by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralizes the acid in the stomach and promotes easy passage of gas to reduce stomach discomfort.
Esoneu-D Capsule SR is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
Most common side effects are diarrhea, flatulence, stomach pain, dryness in mouth, and headache. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. It may also cause sleepiness and dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have liver diseases so that your doctor can prescribe a suitable dose for you.
In Treatment of Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Esoneu-D Capsule SR reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
Side effects of Esoneu-D Capsule SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Esoneu-D
Diarrhea
Flatulence
Stomach pain
Dryness in mouth
Headache
Fundic gland polyps
How to use Esoneu-D Capsule SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esoneu-D Capsule SR is to be taken empty stomach.
How Esoneu-D Capsule SR works
Esoneu-D Capsule SR is a combination of two medicines: Domperidone and Esomeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Esomeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Esoneu-D Capsule SR. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Esoneu-D Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Esoneu-D Capsule SR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Esoneu-D Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Esoneu-D Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Esoneu-D Capsule SR may be needed. Please consult your doctor.
Liver
CAUTION
Esoneu-D Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Esoneu-D Capsule SR may be needed. Please consult your doctor. Use of Esoneu-D Capsule SR is not recommended in patients with moderate and severe liver disease.
What if you forget to take Esoneu-D Capsule SR?
If you miss a dose of Esoneu-D Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You have been prescribed Esoneu-D Capsule SR for the treatment of acidity and heartburn.
Take it one hour before the meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
As soon as I go to sleep I start coughing and it stops after i drink water. it feels like as if something has stuck in the throat. it is happening for the past few days. Same happen if i do not drink water for some time. Please help me with the solution.
Dr. Shubhra Chandan Pradhan
ENT
It can be due to acid reflux. Take tab pan D morning and zintac bed time . Try this
What is the reason and perfect treatment for acid reflux?
Dr. Satyam S. Bhavsar
Physician
Hello, Welcome to 1mg consulting, Myself Dr.Satyam, MBBS.For acid reflux , take TAB.PAN-D twice a day half hour before food for 2 weeks.SYR.DIGENE 2 spoons before bedtime for 2 weeks.Avoid spicy food & fasting.Hope this helps.Happy to help you. Have a nice day :-)
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed
My cough is not getting cured since 4-6 months. Tried some doctors, their medicines work for some time and the dry cough starts again. Though it happens occasionally, but i still cough
Dr. Shubhra Chandan Pradhan
ENT
It can be allergic cough or acid reflux disease. Can't give more opinion without seeing
Esoneu-D Capsule SR is a combination of two medicines: Domperidone and Esomeprazole. This combination is used to treat acidity and heartburn or gastroesophageal reflux disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus). It is also used to treat gastric and duodenal ulcers. Domperidone helps to control vomiting by increasing the movement of the gut, allowing the food to move more easily through the stomach.
Is it safe to use Esoneu-D Capsule SR?
Yes, Esoneu-D Capsule SR is safe for most of the patients. However, in some patients it may cause common side effects like diarrhoea, stomach pain, flatulence, dryness in mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.
What is the best time to take Esoneu-D Capsule SR?
It is best to take Esoneu-D Capsule SR before the first meal of the day or on an empty stomach.
Can the use of Esoneu-D Capsule SR cause abnormal heartbeat?
Yes, the use of Esoneu-D Capsule SR can increase the risk of irregular heartbeat (serious arrhythmias). This is a serious side effect but the chance that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.
What are the contraindications associated with the use of Esoneu-D Capsule SR?
The use of Esoneu-D Capsule SR is considered to be harmful for patients with a known hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.
Can the use of Esoneu-D Capsule SR cause dry mouth?
Yes, the use of Esoneu-D Capsule SR can cause dry mouth. Dryness of mouth occurs due to Domperidone. If you experience dry mouth, drink plenty of water. Take regular sips of water during the day and keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use can increase the risk of tooth decay.
Can the use of Esoneu-D Capsule SR cause diarrhea?
Yes, the use of Esoneu-D Capsule SR can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and if you notice signs of dehydration, like less frequency of urination and dark colored and strong-smelling urine. Avoid taking fatty or fried foods with this medication. Also, do not take any medicines without consulting the doctor.
What are the storage conditions for Esoneu-D Capsule SR?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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Esomeprazole. Luton, UK: AstraZeneca UK Ltd.; 2018. [Accessed 12 Apr. 2019] (online) Available from:
International Breastfeeding Center. Domperidone. [Accessed 12 Apr. 2019] (online) Available from:
Esomeprazole Magnesium and Domperidone Sustained Release [Patient Information Leaflet].Ahmedabad, Gujarat: TORRENT PHARMACEUTICALS LTD.; 2022. [Accessed 28th Sept. 2023] (online) Available from:
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Country of origin: India
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