EX Duo 50 Tablet
Prescription Required
Product introduction
EX Duo 50 Tablet is a combination of two medicines used to treat heart failure. It reduces the risk of hospitalization and death in patients with long-lasting (chronic) heart failure. It is generally given along with other heart failure medications.
EX Duo 50 Tablet may be taken with or without food. Take it at the same time each day for maximum benefits. Your doctor will decide the dose and how often you take it, and it may change depending on how well you respond to the medicine. Keep taking the tablets regularly, as prescribed, and try not to miss doses to get the most benefit. Do not stop taking them, even if you are feeling well. The medicine prevents future complications.
Common side effects of this medicine include low blood pressure (hypotension), impaired renal function, high potassium levels in the blood (hyperkalemia), cough, and dizziness. To reduce the risk of dizziness that may be caused by low blood pressure, try getting up slowly from a sitting or lying position. Tell your doctor if these or other side effects are severe or do not go away.
Before taking this medicine, tell your doctor if you are taking any other medication for blood pressure or heart conditions or if you have kidney or liver disease. Also, let your doctor know all other medications you are using as they may affect, or be affected by, this medicine. This medicine should not be taken during pregnancy and is not recommended while breastfeeding. While on treatment with this medicine, your doctor may advise regular monitoring of blood pressure and regular kidney function.
Uses of EX Duo Tablet
Benefits of EX Duo Tablet
In Treatment of Heart failure
Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen, and other body parts. EX Duo 50 Tablet is a combination of two medicines, namely valsartan and sacubitril. Both of these medicines work in different ways to lower blood pressure. This makes it easier for your heart to pump blood around your body and is, therefore, an effective treatment for heart failure.
This medicine will help relieve your symptoms, making you feel better and more energetic. To help this medicine be effective, you should make appropriate lifestyle changes (such as eating healthily and staying active). Take it regularly and keep taking it even if you feel better.
This medicine will help relieve your symptoms, making you feel better and more energetic. To help this medicine be effective, you should make appropriate lifestyle changes (such as eating healthily and staying active). Take it regularly and keep taking it even if you feel better.
Side effects of EX Duo Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of EX Duo
- Hypotension (low blood pressure)
- Increased potassium level in blood
- Cough
- Dizziness
- Renal impairment
How to use EX Duo Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. EX Duo 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How EX Duo Tablet works
EX Duo 50 Tablet is a combination of two medicines: Sacubitril and Valsartan which belong to a class of angiotensin receptor neprilysin inhibitor (ARNI). This combination treats heart failure by relaxing the blood vessels and making it easier for your heart to pump blood throughout your body. In addition, it also helps your body retain less water.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with EX Duo 50 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
EX Duo 50 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
EX Duo 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
EX Duo 50 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
EX Duo 50 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of EX Duo 50 Tablet may be needed. Please consult your doctor.
Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.
Regular blood pressure monitoring is recommended. No dose adjustment is needed in patients with mild to moderate kidney disease.
Liver
CAUTION
EX Duo 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of EX Duo 50 Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate liver disease.
No dose adjustment is recommended in patients with mild to moderate liver disease.
What if you forget to take EX Duo Tablet?
If you miss a dose of EX Duo 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
EX Duo 50 Tablet
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Quick tips
- You have been prescribed EX Duo 50 Tablet for the treatment of long-lasting (chronic) heart failure.
- You should continue to be active (light walking, stretching) and eat a healthy, low-sodium diet while taking this medication.
- To reduce the chances of feeling dizzy, rise slowly if sitting or lying down.
- It may raise the level of potassium in your blood. Avoid taking potassium supplements and eating potassium-rich foods such as bananas and broccoli.
- Inform your doctor if you have a history of liver or kidney diseases.
- Do not take EX Duo 50 Tablet if you are pregnant or breastfeeding.
Fact Box
Habit Forming
No
Therapeutic Class
CARDIAC
Patient concerns
FAQs
Q. Who should avoid taking EX Duo 50 Tablet?
Patients who are allergic to any of its components should avoid EX Duo 50 Tablet. Those who are allergic to the use of ACE inhibitors or ARBs should also avoid using this medicine. It should not be used along with other antihypertensive medicines. Do not take it for at least 36 hours before or after you take an ACE inhibitor medicine. If you are not sure, consult your doctor.
Q. What should I tell my doctor before taking EX Duo 50 Tablet?
Tell your doctor about all of your medical conditions, including liver or kidney disease and a history of facial swelling (angioedema). Inform him if you are pregnant or are breastfeeding. Also, inform your doctor about all medicines you are taking, especially potassium supplements or medicine salt, painkillers, blood pressure, or heart failure medicines (such as ACE inhibitors, ARBs, or Aliskiren).
Q. Can I use EX Duo 50 Tablet in pregnancy?
No, EX Duo 50 Tablet should be avoided in pregnancy. Its use can cause injury or even endanger the life of the baby. If you become pregnant while using EX Duo 50 Tablet, stop using it and contact your doctor immediately.
Q. How would I know if I have high potassium levels?
Your doctor will check your blood potassium levels periodically to detect high potassium levels (hyperkalemia). Make sure that you do not miss any scheduled appointments with the doctor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Medscape. Sacubitril+Valsartan. [Accessed 24 Apr. 2019] (online) Available from:
- Sacubitril+Valsartan. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2015 [revised Nov. 2018]. [Accessed 24 Apr. 2019] (online) Available from:
- Sacubitril and Valsartan [Prescribing Information]. Telangana, India: MSN Laboratories Private Limited; 2023. [Accessed 28th Sept. 2023] (online) Available from:
- Sacubitril and Valsartan [Product Monograph]. Dublin 4, Ireland: Novartis Europharm Limited.2020. [Accessed 28th Sept. 2023] (online) Available from:
- Sacubitril and valsartan [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2024. [Accessed Oct. 10, 2024] (online) Available from:
Marketer details
Name: Emcure Pharmaceuticals Ltd
Address: 255/2, Hinjawadi, Pune - 411057, India
Country of origin: India
Expires on or after: March, 2026
A licensed vendor partner from your nearest location will deliver EX Duo 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2026
A licensed vendor partner from your nearest location will deliver EX Duo 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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