Fisofine Cream is a combination of two medicines used in the treatment of anal fissures (tear in the lining of the anus). It relieves the pain, swelling, itching, and discomfort associated with passing of stools in people who suffer from problems in the anal area.

Fisofine Cream relaxes the blood vessels in the anus thus helping in the healing of anal fissures. It should be used in the dose and duration as directed by your doctor. Clean and dry the affected area before applying this medicine. Make sure to wash your hands thoroughly before and after applying this medicine. Do not use your finger to apply this medicine. Do not stop using it suddenly without talking to your doctor, as it may lead to worsening of your condition.

This medicine is generally well tolerated with minimal or no side effects. However, slight anal irritation may occur as a side effect of this medicine. This is temporary and usually resolves on its own in some time. Please consult your doctor if it does not resolve or persists for a longer duration.

Avoid getting it into your eyes, nose, or mouth. If accidental exposure occurs, wash your eyes with water and seek immediate medical attention. You should stop using it and inform your doctor if you notice worsening of the infection or if you develop increased redness and irritation.

Uses of Fisofine Cream

Treatment of Anal fissure

Benefits of Fisofine Cream

In Treatment of Anal fissure

Fisofine Cream is used to relieve pain, irritation, or itching caused by anal fissures (tear in the lining of the anus). It relaxes the blood vessels thereby decreasing the pressure in the anal tissues. Use it in the dose and duration as advised by your doctor.

Side effects of Fisofine Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Fisofine

Anal irritation

How to use Fisofine Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Fisofine Cream works

Fisofine Cream is a combination of two medicines: Lidocaine and Nifedipine. Lidocaine is a local anesthetic. It works by blocking pain signals from the nerves to brain which decreases pain sensation. Nifedipine is a calcium channel blocker (CCB). It works in anal fissure by blocking the action of calcium on blood vessels of anus.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Fisofine Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Fisofine Cream is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Fisofine Cream

₹3.01/gm of Cream

Xylocaine NF Cream

Zydus Cadila

₹7/gm of cream

133% costlier

Loxheal Cream

Neon Laboratories Ltd

₹3.6/gm of cream

20% costlier

Anofresh NL Cream

Anoveda Healthcare Pvt Ltd

₹4.6/gm of cream

53% costlier

Quick tips

It is for administration into the rectum (back passage). It must not be taken by mouth.
Use the applicator provided to insert a measured dose of cream into your back passage.
Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
Tips to treat constipation caused by anal fissure:
- Drink plenty of fluids to stay hydrated.
- Have fiber-rich food such as whole grains, oatmeal, and citrus fruits.
- Exercise regularly.
- Do not sit on the toilet for too long.
- Do not ignore your urge to go to the washroom.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

I occasionally find blood in my stool.

Dr. Sfurti Mann

Internal Medicine

May be anal fissure, get yourself examined by a surgeon.

Fissure and fistula of anal region Fissure and fistula of anal and rectal region

Dr. Pushkar Mani

Physician

refer to surgeon again

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Perrotti P, Dominici P, Grossi E, et al. Topical nifedipine with lidocaine ointment versus active control for pain after hemorrhoidectomy: results of a multicentre, prospective, randomized, double-blind study. Can J Surg. 2010;53(1):17-24. [Accessed 17 Feb. 2020] (online) Available from:
Drugs.com. Lidocaine. [Accessed 19 Apr. 2019] (online) Available from:
Drugs.com. Nifedipine. [Accessed 19 Apr. 2019] (online) Available from:

Marketer details

Name: Altova Healthcare

Address: Unit G-2, Ground Floor, New Udyog Mandir, 7-C Mogal Lane, Mahim (W), Mumbai - 400016 India

Country of origin: India

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