Fludabine 50mg Injection is used in the treatment of blood cancer called chronic lymphocytic leukemia (CLL). It may be used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Fludabine 50mg Injection is given as infusion into veins under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, weakness, fever, and cough. This medicine may reduce the number of blood cells (decrease white blood cells and red blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Fludabine Injection

Blood cancer (Chronic lymphocytic leukemia)

Benefits of Fludabine Injection

In Blood cancer (Chronic lymphocytic leukemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Fludabine 50mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.

Side effects of Fludabine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Fludabine

Increased risk of infection
Vomiting
Weakness
Nausea
Fatigue
Fever
Decreased blood cells (red cells, white cells, and platelets)
Diarrhea
Cough

How to use Fludabine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Fludabine Injection works

Fludabine 50mg Injection is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells in blood. This slows the growth of cancer cells and eventually kills them.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Fludabine 50mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Fludabine 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Fludabine 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Fludabine 50mg Injection may cause side effects which could affect your ability to drive.
Some people get tired, feel weak, have disturbed vision, become confused, or agitated or have seizures while they are treated with Fludabine 50mg Injection and this may affect your ability to drive.

Kidney

CAUTION

Fludabine 50mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Fludabine 50mg Injection may be needed. Please consult your doctor.
Use of Fludabine 50mg Injection is not recommended in patients with severe kidney disease.

Liver

CAUTION

Fludabine 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Fludabine 50mg Injection may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Fludabine 50mg Injection

₹10180/Injection

Emmdara 50mg Injection

Emcure Pharmaceuticals Ltd

₹12500/injection

19% costlier

Fludasted 50 Injection

Halsted Pharma Private Limited

₹8100/injection

23% cheaper

Fludarither 50 Injection

Therdose Pharma Pvt Ltd

₹6400/injection

39% cheaper

Fludacel 50mg Injection

Celon Laboratories Ltd

₹6500/injection

38% cheaper

Fludocyte 50mg Injection

Intas Pharmaceuticals Ltd

₹10277.13/injection

2% cheaper

Quick tips

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Fact Box

Chemical Class

Purine nucleosides Analog

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

Patient concerns

She is suffering from chronic myeloid leukemia

Dr. Deepak Kumar Soni

Ayurveda

Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.

I want to know the symptoms of cancer as I am a smoker

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.

Related lab tests

Complete Blood Count

Peripheral Smear Examination

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1702-703.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 948.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 555-56.
Fludarabine phosphate. Bedford, Ohio: Ben Venue Laboratories. [Accessed 27 Mar. 2017] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

Name: United Biotech Pvt Ltd

Address: FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044

Country of origin: India

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