Fludara Injection
Prescription Required
Product introduction
Fludara Injection is used in the treatment of blood cancer called chronic lymphocytic leukemia (CLL). It may be used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
Fludara Injection is given as infusion into veins under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, weakness, fever, and cough. This medicine may reduce the number of blood cells (decrease white blood cells and red blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Fludara Injection is given as infusion into veins under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, weakness, fever, and cough. This medicine may reduce the number of blood cells (decrease white blood cells and red blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Fludara Injection
Benefits of Fludara Injection
In Blood cancer (Chronic lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Fludara Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.
Side effects of Fludara Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Fludara
- Increased risk of infection
- Vomiting
- Weakness
- Nausea
- Fatigue
- Fever
- Decreased blood cells (red cells, white cells, and platelets)
- Diarrhea
- Cough
How to use Fludara Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Fludara Injection works
Fludara Injection is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells in blood. This slows the growth of cancer cells and eventually kills them.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Fludara Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Fludara Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Fludara Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Fludara Injection may cause side effects which could affect your ability to drive.
Some people get tired, feel weak, have disturbed vision, become confused, or agitated or have seizures while they are treated with Fludara Injection and this may affect your ability to drive.
Some people get tired, feel weak, have disturbed vision, become confused, or agitated or have seizures while they are treated with Fludara Injection and this may affect your ability to drive.
Kidney
CAUTION
Fludara Injection should be used with caution in patients with kidney disease. Dose adjustment of Fludara Injection may be needed. Please consult your doctor.
Use of Fludara Injection is not recommended in patients with severe kidney disease.
Use of Fludara Injection is not recommended in patients with severe kidney disease.
Liver
CAUTION
Fludara Injection should be used with caution in patients with liver disease. Dose adjustment of Fludara Injection may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Fludara Injection
₹11465/Injection
Fludasted 50 Injection
Halsted Pharma Private Limited
₹8100/injection
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Emmdara 50mg Injection
Emcure Pharmaceuticals Ltd
₹12500/injection
6% costlier
Fludarither 50 Injection
Therdose Pharma Pvt Ltd
₹6400/injection
46% cheaper
Fludacel 50mg Injection
Celon Laboratories Ltd
₹6500/injection
45% cheaper
Fludocyte 50mg Injection
Intas Pharmaceuticals Ltd
₹10277.13/injection
13% cheaper
Quick tips
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Fact Box
Chemical Class
Purine nucleosides Analog
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites
Interaction with drugs
Taking Fludara with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Fludarabine from 1 day before until 1 day after taking Sargramostim. P
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Fludarabine from 1 day before until 1 day after taking Molgramostim. P
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Fludarabine from 14 days before until 24 days after taking Pegfilgrast
Concomitant use may increase the risk of opportunistic infections.
Do not consume Natalizumab with Fludarabine.
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1702-703.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 948.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 555-56.
- Fludarabine phosphate. Bedford, Ohio: Ben Venue Laboratories. [Accessed 27 Mar. 2017] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Sanofi India Ltd
Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072
Country of origin: India
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