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MMST, MBBS
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MD Pharmacology, MBBS
Last updated
05 Nov 2024 | 01:00 AM (IST)

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Flutamide 250mg Tablet

Prescription Required
Marketer
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Flutamide 250mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Flutamide 250mg Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Breast enlargement in males, sleepiness, nausea, and vomiting are some very common side effects of this medicine. Other than this, yellowing of the skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes are some side effects that require immediate action. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.  You may be asked for regular monitoring of blood glucose levels while on treatment.

Uses of Flutamide Tablet

Benefits of Flutamide Tablet

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Flutamide 250mg Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Flutamide Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Flutamide

  • Breast enlargement in male
  • Sleepiness
  • Nausea
  • Abdominal pain
  • Anemia (low number of red blood cells)
  • Breast tenderness
  • Constipation
  • Decreased appetite
  • Decreased libido
  • Depression
  • Dizziness
  • Indigestion
  • Flatulence
  • Hot flashes
  • Increased liver enzymes
  • Rash
  • Weakness
  • Weight gain
  • Vomiting

How to use Flutamide Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Flutamide 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Flutamide Tablet works

Flutamide 250mg Tablet blocks the effect of the natural male hormones on the growth of prostate cells. Flutamide 250mg Tablet also blocks the undesired effects of androgens in females such as excessive hair growth and acne.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Flutamide 250mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Flutamide 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Flutamide 250mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Flutamide 250mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Flutamide 250mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Flutamide 250mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
UNSAFE
Flutamide 250mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
"You should not take EUFLEX tablets if you have liver problems or if you are allergic to it. Women should not take EUFLEX tablets. https://hemonc.org/docs/packageinsert/flutamide.pdf

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Flutamide 250mg Tablet
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Quick tips

  • You have been prescribed Flutamide 250mg Tablet for the treatment of prostate cancer.
  • Take it with or without food, preferably at the same time every day.
  • Do not drive or do anything requiring concentration unless you know how Flutamide 250mg Tablet affects you.
  • It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
  • If you are diabetic, monitor your blood glucose regularly while taking Flutamide 250mg Tablet.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Do not stop taking the medication without talking to your doctor first.

Fact Box

Chemical Class
Trifluoromethylbenzene Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Androgen receptor antagonist

Patient concerns

arrow
Is flutamide topical safe and effective for androgenic alopecia?
Dr. Atul Jain
Dermatology
new in market, not FDA aprroved
I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
May not be prostate cancer, it is only begnin enlargement of prostate.
arrow

User feedback


FAQs

Q. Does flutamide lower testosterone?

Yes, flutamide lowers testosterone levels and blocks testosterone from reaching the cancer cells, thereby slowing the growth and of cancer cells.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 724.
  2. Flutamide. Kenilworth, New Jersey: Schering Corporation; 2000. [Accessed 27 Mar. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  4. Flutamide. Potters Bar: Generics [UK] Ltd t/a Mylan; 22 Dec. 1997 [revised 4 May. 2015]. [Accessed] (online) Available from:External Link

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India

87.3
Inclusive of all taxes
MRP90  3% OFF
10.0 tablets in 1 strip
SOLD OUT
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