Ganace 400mg/10mg Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.

Ganace 400mg/10mg Tablet is taken by mouth, with or without food and preferably at night. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor as it may worsen your symptoms.
Some common side effects of this medicine constipation, difficulty in urination, weight gain, tiredness, and dryness in mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. Remember to inform the doctor if you develop any unusual changes in mood as this medicine may lead to suicidal thoughts.
Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Ganace Tablet

Treatment of Neuropathic pain

Benefits of Ganace Tablet

In Treatment of Neuropathic pain

Ganace 400mg/10mg Tablet is a combination medicine used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain.

Side effects of Ganace Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ganace

Dryness in mouth
Decreased white blood cell count
Peripheral edema
Weakness
Impotence
Indigestion
Insomnia (difficulty in sleeping)
Tiredness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Increased heart rate
Uncoordinated body movements
Constipation
Difficulty in urination
Weight gain
Sleepiness
Dizziness
Blurred vision

How to use Ganace Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ganace 400mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Ganace Tablet works

Ganace 400mg/10mg Tablet is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

Safety advice

Alcohol

UNSAFE

Ganace 400mg/10mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Ganace 400mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Ganace 400mg/10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Ganace 400mg/10mg Tablet may cause side effects which could affect your ability to drive.
As Ganace 400mg/10mg Tablet may affect your alertness which may affect your ability to drive.

Kidney

CAUTION

Ganace 400mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Ganace 400mg/10mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Ganace 400mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Ganace 400mg/10mg Tablet may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Ganace 400mg/10mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Ganace Tablet?

If you miss a dose of Ganace 400mg/10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Ganace 400mg/10mg Tablet

₹26.2/Tablet

Gabanyl NT 400mg/10mg Tablet

Leeford Healthcare Ltd

₹14.1/tablet

46% cheaper

Gabadon-NTP 400mg/10mg Tablet

Knoll Pharmaceuticals Ltd

₹17.7/tablet

32% cheaper

Gabapin NT Tablet

Intas Pharmaceuticals Ltd

₹33.07/tablet

26% costlier

Doloneuron NT Tablet

Pulse Pharmaceuticals

₹27.1/tablet

3% costlier

Laregab NT 400mg/10mg Tablet

La Renon Healthcare Pvt Ltd

₹27.7/tablet

6% costlier

View all substitutes

Quick tips

Ganace 400mg/10mg Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
Inform your doctor if you are taking any other pain-relieving medicines.
Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
Avoid taking antacids 2 hours before or after taking Ganace 400mg/10mg Tablet as they make it harder for your body to absorb the medicine.
Ganace 400mg/10mg Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
Inform your doctor if you are taking any other pain-relieving medicines.
Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
Avoid taking antacids 2 hours before or after taking Ganace 400mg/10mg Tablet as they make it harder for your body to absorb the medicine.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

Patient concerns

Most of the times when I get excited or have orgasm I feel pain in my testis and around it .

Dr. Pranay Gandhi

Sexology

hi PATIENT neuropathic pain mostly. take tablet emanzen d 1 bd

Sir Plz suggest me effective pain killer with minimum side effects for back pain and arthritis, which can be taken on regular basis as and when required.

Dr. Vikas Sharma

Neurology

dpeneds on the type of pain - muscular or neuropathic; show tro nearby neuro

I m suffering due to pain in left testis, so I visited pgimer Chandigarh in urology deptt. There I had gone for dopler ultrasound testis and its reports are normal Now whenever I lay down at bed I felt a smaal lump in testis,when I touchdown it, the pain radiates in whole left testis Now I m feeling pain sometimes in both tastis Is it a sign of early vericoseal Or something else Pls. Suggest

Dr. Pranay Gandhi

Sexology

it is a neuropathic pain and it won't show any abnormality in USG. i am worried about the lump u r talking about. its better if u consult a surgeon, PGIMER UROLOGY is the best place to go for examination. if they say its normal, its normal. for pain take pregaba m 1 od

FAQs

What is Ganace 400mg/10mg Tablet?

Ganace 400mg/10mg Tablet is a combination of two medicines: Gabapentin and Nortriptyline. This medicine is useful in the treatment of nerve pain (Neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, it decreases the pain sensation.

Can I stop taking Ganace 400mg/10mg Tablet when my pain is relieved?

No, you should not stop taking Ganace 400mg/10mg Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Ganace 400mg/10mg Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.

How to manage weight gain associated with the use of Ganace 400mg/10mg Tablet?

Ganace 400mg/10mg Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.

Can the use of Ganace 400mg/10mg Tablet affect my sexual life?

The use of Ganace 400mg/10mg Tablet can affect the sexual life of both men and women. Most commonly observed problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking Ganace 400mg/10mg Tablet.

Are there any serious side effects associated with the use of Ganace 400mg/10mg Tablet?

Serious side effects because of Ganace 400mg/10mg Tablet are uncommon and rare. Consult your doctor immediately if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.

How long will the Ganace 400mg/10mg Tablet take to act?

An initial benefit with Ganace 400mg/10mg Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.

What if I forget to take Ganace 400mg/10mg Tablet?

If you forget to take the scheduled dose of Ganace 400mg/10mg Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect due to overdosage. If you are not sure what to do, ask your doctor about taking Ganace 400mg/10mg Tablet.

What if I take too much of this drug by mistake?

In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Overdose of this medicine may make you feel drowsy, weak, unsteady when walking, have double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.

Is there anything I need to avoid while taking Ganace 400mg/10mg Tablet?

Ganace 400mg/10mg Tablet may impair your thinking or reactions. Be careful while driving or while doing any activity that requires you to be alert. Do not drink alcohol while you are taking Ganace 400mg/10mg Tablet. It can increase the effects of alcohol which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Ganace 400mg/10mg Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.

How often should I see the doctor?

You may need to see your doctor regularly if you have started to take Ganace 400mg/10mg Tablet. However, you must consult your doctor if the advised dosage of Ganace 400mg/10mg Tablet does not improve your symptoms or you continue experiencing unwanted side effects that affect your routine activities.

Can the use of Ganace 400mg/10mg Tablet cause sleepiness or drowsiness?

Yes, Ganace 400mg/10mg Tablet may make you feel drowsy or may cause you to suddenly fall asleep during your daily activities. You might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medication affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

Will Ganace 400mg/10mg Tablet be more effective if taken more than recommended dose?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

What are the storage condition for Ganace 400mg/10mg Tablet?

Keep your tablets in the pack until it is time to take them. Store them in a cool dry place. Store them out of sight and out of reach of children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Nortriptyline. Ballybofey, County Donegal: Pharmaceuticals Ltd.; 2010 [revised 22 Feb. 2019]. [Accessed 25 Mar. 2019] (online) Available from:
Gabapentin. Menlo Park: Depomed; 1993 [revised date]. [Accessed 22 Apr. 2019] (online) Available from:
Drugs.com. Nortriptyline. [Accessed 22 Apr. 2019] (online) Available from:
Gabapentin & Nortriptyline Hydrochloride [Patient Information Sheet]. Ahmedabad, Gujarat: TORRENT PHARMACEUTICALS LTD.; 2021. [Accessed 28th Sept. 2023] (online) Available from:

Marketer details

Name: Solace Remedies Private Limited

Address: FLAT NO. 107, B WING, PARAMOUNT SWAMIDHAM, S.NO. 48/1A/1/2, KONDHWA BUDRUK, PUNE Pune MH 411048 IN

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.