Gazin M 40 mg/500 mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Gazin M 40 mg/500 mg Tablet should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Gazin M 40 mg/500 mg Tablet are low blood glucose levels (hypoglycemia), constipation, and vomiting. Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Gazin M Tablet

Type 2 diabetes mellitus

Side effects of Gazin M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gazin M

Hypoglycemia (low blood glucose level)
Headache
Dizziness
Diarrhea
Upper respiratory tract infection
Nausea
Flatulence
Constipation

How to use Gazin M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gazin M 40 mg/500 mg Tablet is to be taken with food.

How Gazin M Tablet works

Gazin M 40 mg/500 mg Tablet is a combination of two antidiabetic medicines: Gliclazide and Metformin.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Gazin M 40 mg/500 mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Gazin M 40 mg/500 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Gazin M 40 mg/500 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Gazin M 40 mg/500 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Gazin M 40 mg/500 mg Tablet may be needed. Please consult your doctor.
Use of Gazin M 40 mg/500 mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

CAUTION

Gazin M 40 mg/500 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Gazin M 40 mg/500 mg Tablet may be needed. Please consult your doctor.
Gazin M 40 mg/500 mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

What if you forget to take Gazin M Tablet?

If you miss a dose of Gazin M 40 mg/500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Gazin M 40 mg/500 mg Tablet

₹5.83/Tablet

Semi Reclimet 40mg/500mg Tablet

Dr Reddy's Laboratories Ltd

₹8.3/tablet

42% costlier

Cyblex M 40 Tablet

Eris Lifesciences Ltd

₹8/tablet

37% costlier

Loyzide M 40mg/500mg Tablet

Lloyd Healthcare Pvt Ltd

₹6.33/tablet

9% costlier

Glychek-M Plus Tablet

Indoco Remedies Ltd

₹7.6/tablet

30% costlier

Semi Curezide M Tablet

Curega Healthcare Pvt Ltd

₹5.82/tablet

same price

View all substitutes

Quick tips

Monitor your blood sugar level regularly while you are taking this medicine.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Gazin M 40 mg/500 mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Monitor your blood sugar level regularly while you are taking this medicine.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Gazin M 40 mg/500 mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt

Physician

Go for allopathic medicine

Any latest discoveris for type 1 mellitus Diabetes?

Dr. Sanjay Bhatt

Physician

Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

How to manage diabetes mellitus

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

User feedback

What are you using Gazin M Tablet for?

Type 2 diabet*

100%

*Type 2 diabetes mellitus

How much was the improvement?

Poor

100%

FAQs

What is Gazin M 40 mg/500 mg Tablet?

Gazin M 40 mg/500 mg Tablet is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Gliclazide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

What are the possible side effects of Gazin M 40 mg/500 mg Tablet?

The use of Gazin M 40 mg/500 mg Tablet is associated with common side effects. These side effects may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Can the use of Gazin M 40 mg/500 mg Tablet cause hypoglycemia?

Yes, the use of Gazin M 40 mg/500 mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

Can the use of Gazin M 40 mg/500 mg Tablet cause lactic acidosis?

Yes, the use of Gazin M 40 mg/500 mg Tablet can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin. It is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Gazin M 40 mg/500 mg Tablet and immediately consult your doctor.

Can the use of Gazin M 40 mg/500 mg Tablet lead to Vitamin B12 deficiency?

Yes, the use of Gazin M 40 mg/500 mg Tablet can cause vitamin B12 deficiency on long-term use. The deficiency occurs as the medicine interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Are there any specific conditions in which Gazin M 40 mg/500 mg Tablet should not to be taken?

The use of Gazin M 40 mg/500 mg Tablet should be avoided in patients with known allergy to any of the component or excipients of this medicine. It is also avoided in patients with moderate to severe kidney disease or with underlying metabolic acidosis including diabetic ketoacidosis.

Is it safe to take alcohol while I am also taking Gazin M 40 mg/500 mg Tablet?

No, it is not safe to take alcohol along with Gazin M 40 mg/500 mg Tablet. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

What is Gazin M 40 mg/500 mg Tablet?

What are the possible side effects of Gazin M 40 mg/500 mg Tablet?

Can the use of Gazin M 40 mg/500 mg Tablet cause hypoglycemia?

Can the use of Gazin M 40 mg/500 mg Tablet cause lactic acidosis?

Can the use of Gazin M 40 mg/500 mg Tablet lead to Vitamin B12 deficiency?

Are there any specific conditions in which Gazin M 40 mg/500 mg Tablet should not to be taken?

Is it safe to take alcohol while I am also taking Gazin M 40 mg/500 mg Tablet?

No, it is not safe to take alcohol along with Gazin M 40 mg/500 mg Tablet. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Show less

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

Top Diabetologists

Dr. Ambrish Mithal

MBBS, MD, DM

4.5 ★

Dr. Harmandeep K. Gill

4.5 ★

4 ★

MBBS, Diploma, Fellowship

4.3 ★

Dr. Beena Bansal

MBBS, MD, DM

4.4 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Gottwald-Hostalek U, Schlachter J, Geloneze B. Combination Therapy with Metformin plus Gliclazide in Patients with Type 2 Diabetes. J Dia Res Ther. 2016;2(3). [Accessed 08 Apr. 2019] (online) Available from:
Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:
Gliclazide+Metformin [Product Monograph]. Solan, Himachal Pradesh: Panacea Biotec Limited; 2019. [Accessed 23 Sept. 2021] (online) Available from:
American Diabetes Association. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2020. Diabetes Care. 2020;43(Suppl 1): S98-S110. [Accessed 23 Sept. 2021] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 13 Mar. 2019] (online) Available from:
Gliclazide and Metformin [Product Monograph]. Solan, Himachal Pradesh: Panacea Biotec Limited; 2019. [Accessed 28th Sept. 2023] (online) Available from:
Gliclazide and Metformin Hydrochloride (SR) [Prescribing Information]. Bangalore, India: Biocon Limited. [Accessed 28th Sept. 2023] (online) Available from:

Marketer details

Name: Emcure Pharmaceuticals Ltd

Address: 255/2, Hinjawadi, Pune - 411057, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.