Gefires 250mg Tablet
Prescription Required
Product introduction
Gefires 250mg Tablet is used in the treatment of non-small cell lung cancer. It is used in patients in which it has spread to other parts of the body, who have abnormal epidermal growth factor receptor (EGFR) genes, and who have not had previous treatment for cancer.
Gefires 250mg Tablet should be taken in a dose as recommended by the doctor. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Your doctor may advice for regular monitoring of liver function while your taking this medicine.
Common side effects include diarrhea, dry skin, loss of appetite, and nausea. Drink plenty of fluids to reduce the risk of side effects. Inform your doctor if any of the side effects bother you or get worse. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor.
Women who are undergoing treatment should use effective contraception method. It is important to avoid pregnancy during the treatment and for a month after completing the course of medicine. Let your doctor also know about all the other medications you are taking.
Uses of Gefires Tablet
Benefits of Gefires Tablet
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Gefires 250mg Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Gefires Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gefires
- Diarrhea
- Dry skin
- Loss of appetite
- Nausea
- Rash
- Vomiting
- Weakness
- Weight loss
- Eating disorder
- Allergic reaction
How to use Gefires Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gefires 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Gefires Tablet works
Gefires 250mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Gefires 250mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Gefires 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Gefires 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Gefires 250mg Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Gefires 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Gefires 250mg Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Gefires 250mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Gefires 250mg Tablet may not be needed in these patients. Please consult your doctor.
What if you forget to take Gefires Tablet?
If you miss a dose of Gefires 250mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Gefires 250mg Tablet
₹110.0/Tablet
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Quick tips
- Gefires 250mg Tablet helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
- Take it with or without food, preferably at the same time each day.
- Do not take antacids (to reduce the acid level of your stomach) 2 hours before or 1 hour after taking this medicine.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of breath, or breathing difficulties while taking this medicine.
- Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
Fact Box
Chemical Class
Quinazolinamines
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine kinase inhibitors
Interaction with drugs
Taking Gefires with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause a reduction in white blood cell levels.
Do not consume Vincristine with Gefitinib.
Concomitant use may cause a reduction in white blood cell levels.
Do not consume Vinblastine with Gefitinib.
Concomitant use may cause a reduction in white blood cell levels.
Do not consume Gefitinib with Vinorelbine.
Dronedarone may raise blood levels of Gefitinib.
watch out for symptoms of Dronedarone side effects such as diarrhea, dry eye, vomiting, breathing problems, decreased appetite or
Enzalutamide may reduce blood levels of Gefitinib.
Do not consume Gefitinib with Enzalutamide. If concurrent use is essential, your doctor may monitor your treatment and adjust th
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1734-35.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 954-55.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 616-17.
- Gefitinib. Luton, Bedfordshire: AstraZeneca UK Limited; 2009 [revised 23 Apr. 2018]. [Accessed 232 Jan. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Gefitinib. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
- CiplaMed. Gefitinib [Prescribing Information]. [Accessed 06 Apr. 2024] (online) Available from:
Marketer details
Name: Resonance Laboratories Pvt Ltd
Address: 1, Noor Mahal, 19-D, Turner Road, Bandra, Mumbai-400050
Country of origin: India
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