Geftinat 250mg Tablet is used in the treatment of non-small cell lung cancer. It is used in patients in which it has spread to other parts of the body, who have abnormal epidermal growth factor receptor (EGFR) genes, and who have not had previous treatment for cancer.

Geftinat 250mg Tablet should be taken in a dose as recommended by the doctor. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Your doctor may advice for regular monitoring of liver function while your taking this medicine.

Common side effects include diarrhea, dry skin, loss of appetite, and nausea. Drink plenty of fluids to reduce the risk of side effects. Inform your doctor if any of the side effects bother you or get worse. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor.

Women who are undergoing treatment should use effective contraception method. It is important to avoid pregnancy during the treatment and for a month after completing the course of medicine. Let your doctor also know about all the other medications you are taking.

Uses of Geftinat Tablet

Non-small cell lung cancer

Benefits of Geftinat Tablet

In Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Geftinat 250mg Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Geftinat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Geftinat

Diarrhea
Dry skin
Loss of appetite
Nausea
Rash
Vomiting
Weakness
Weight loss
Eating disorder
Allergic reaction

How to use Geftinat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Geftinat 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Geftinat Tablet works

Geftinat 250mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Geftinat 250mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Geftinat 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Geftinat 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Geftinat 250mg Tablet may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Geftinat 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Geftinat 250mg Tablet may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Geftinat 250mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Geftinat 250mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Geftinat Tablet?

If you miss a dose of Geftinat 250mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Geftinat 250mg Tablet

₹192.53/Tablet

Geftistar 250mg Tablet

Lupin Ltd

₹115.1/tablet

40% cheaper

Geftisted 250mg Tablet

Halsted Pharma Private Limited

₹176/tablet

9% cheaper

Unigef 250mg Tablet

Samarth Life Sciences Pvt Ltd

₹143.1/tablet

26% cheaper

Ultragef 250mg Tablet

Bangalore Antibiotics & Biologicals Pvt Ltd

₹235/tablet

22% costlier

Gefticip Tablet

Cipla Ltd

₹172.07/tablet

11% cheaper

View all substitutes

Quick tips

Geftinat 250mg Tablet helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
Take it with or without food, preferably at the same time each day.
Do not take antacids (to reduce the acid level of your stomach) 2 hours before or 1 hour after taking this medicine.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of breath, or breathing difficulties while taking this medicine.
Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.

Fact Box

Chemical Class

Quinazolinamines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine kinase inhibitors

Interaction with drugs

Taking Geftinat with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Vincristine (Oral Route) Life-threatening

Concomitant use may cause a reduction in white blood cell levels. Do not consume Vincristine with Gefitinib.

Vinblastine (Oral Route) Life-threatening

Concomitant use may cause a reduction in white blood cell levels. Do not consume Vinblastine with Gefitinib.

Vinorelbine (Injection Route) Life-threatening

Concomitant use may cause a reduction in white blood cell levels. Do not consume Gefitinib with Vinorelbine.

Aprepitant (Injection Route) Moderate

Aprepitant may raise blood levels of Gefitinib. watch out for symptoms of Aprepitant side effects such as diarrhea, dry eye, vomiting, breathing problems, decreased appetite or ra... More

Bosentan (Oral Route) Moderate

Bosentan may reduce blood levels of Gefitinib. Do not consume Gefitinib with Bosentan. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses ... More

View all drug interactions

Patient concerns

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Dr. Vijay Sharnangat

Medical Oncology and Hematology

This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.

I need to send Geftinat 250MG by NATCO Pharma to my friend in China, but she is asking something 9219. I do not know if the 9219 thing is this same medicine available on 1mg.com. Please suggest.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Please send same medicine geftinate 250 mg to your friend9219 , I also don't know

My father in law is a lung cancer patient.He had gone through two chemo cycles.The first one led to a significant reduction of about 50% in the tumor size.He was administered gemcitabine and carboplatin.However,the 2nd one was ineffective.Please advise as to what could be the next course of action. He was a smoker and has non-small cell carcinoma.The cancer has spread to the adrenal glands.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

U have to do a CT SCAN 3WKS AFTER 3RD CHEMOBased on that u make assessment of response

User feedback

Patients taking Geftinat 250mg Tablet

Once A Day

85%

Alternate Day

Twice A Day

What are you using Geftinat Tablet for?

Small cell lu*

56%

Non-small cel*

31%

Others

14%

*Small cell lung cancer, Non-small cell lung cancer

How much was the improvement?

Average

42%

Poor

31%

Excellent

28%

What were the side-effects while using Geftinat 250mg Tablet?

No Side Effec*

30%

Nausea

20%

Rash

20%

Dry skin

10%

Loss of appet*

10%

*No Side Effect, Loss of appetite

How do you take Geftinat Tablet?

With food

71%

With or witho*

29%

*With or without food

Please rate Geftinat 250mg Tablet on price

Average

44%

Expensive

37%

Not Expensive

19%

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1734-35.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 954-55.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 616-17.
Gefitinib. Luton, Bedfordshire: AstraZeneca UK Limited; 2009 [revised 23 Apr. 2018]. [Accessed 232 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Gefitinib. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
CiplaMed. Gefitinib [Prescribing Information]. [Accessed 06 Apr. 2024] (online) Available from: