GEN 400mg Soft Gelatin Capsule is a natural female sex hormone, progesterone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance.

You should use GEN 400mg Soft Gelatin Capsule as your doctor has advised. Do not use more or less than you have been advised and do not use it for longer than recommended. You may be asked to continue taking this medicine for a period after it is confirmed that you are pregnant.

The most common side effects include headache, feeling very tired, stomach cramps, pain or swelling in your abdomen and feeling sick. You may also feel bloated, less interested in sex and get pain or discharge in your vagina. Your doctor or nurse may be able to help you reduce or prevent side effects if they bother you or do not go away. Very occasionally people get a severe allergic reaction which needs urgent medical attention. Using this medicine may increase your risk of blood clots or breast cancer.

GEN 400mg Soft Gelatin Capsule may not suit everybody, and you should tell your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina or liver disease. You may be monitored more carefully if you have liver, kidney or heart problems or have diabetes or asthma. Let your doctor know your medical history to be safe. Check with your doctor about all other medicines which may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment to check your womb. This medicine can alter your thinking or reactions and you may feel very tired so be careful if you drive or need to be alert. In general, alcohol is not recommended while taking this medicine.

Uses of GEN Soft Gelatin Capsule

Benefits of GEN Soft Gelatin Capsule

In Female infertility

GEN 400mg Soft Gelatin Capsule contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. Progesterone helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.

In Hormone replacement therapy

Hormone Placement Therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

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Side effects of GEN Soft Gelatin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of GEN

Abdominal bloating
Hot flushes
Vaginal discharge
Urinary incontinence
Headache
Fatigue
Joint pain
Cough
Abnormal menstrual bleeding
Musculoskeletal (bone, muscle or joint) pain
Slurred speech
Pain behind eyes
Vertigo

How to use GEN Soft Gelatin Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. GEN 400mg Soft Gelatin Capsule is to be taken empty stomach.

How GEN Soft Gelatin Capsule works

GEN 400mg Soft Gelatin Capsule is a progesterone (female hormone). It works on the lining of the uterus and helps to establish and maintain pregnancy in infertile women. It helps in protecting the uterus from the negative effects of oestrogen when used for the treatment of postmenopausal symptoms.

Safety advice

Alcohol

UNSAFE

GEN 400mg Soft Gelatin Capsule may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

GEN 400mg Soft Gelatin Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

GEN 400mg Soft Gelatin Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

GEN 400mg Soft Gelatin Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of GEN 400mg Soft Gelatin Capsule in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of GEN 400mg Soft Gelatin Capsule in patients with liver disease. Please consult your doctor.

What if you forget to take GEN Soft Gelatin Capsule?

If you miss a dose of GEN 400mg Soft Gelatin Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

GEN 400mg Soft Gelatin Capsule

₹49.4/Soft Gelatin Capsule

Naturogest 400mg Soft Gelatin Capsule

Zydus Cadila

₹61.5/soft gelatin capsule

24% costlier

Dubagest 400 Soft Gelatin Capsule

Integrace Pvt Ltd

₹86.1/soft gelatin capsule

74% costlier

Gestofit 400 Soft Gelatin Capsule

Alembic Pharmaceuticals Ltd

₹58.5/soft gelatin capsule

18% costlier

C-Hop 400mg Soft Gelatin Capsule

Corona Remedies Pvt Ltd

₹68.75/soft gelatin capsule

39% costlier

Endogest 400mg Soft Gelatin Capsule

Cipla Ltd

₹55.6/soft gelatin capsule

13% costlier

Quick tips

GEN 400mg Soft Gelatin Capsule is used in the treatment of female infertility and as a part of hormone replacement therapy.
It regulates menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.
It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).
It should be taken without food, preferably in the evening or at bedtime.
It may cause sleepiness or drowsiness. Don't drive or do anything that requires mental focus until you know how GEN 400mg Soft Gelatin Capsule affects you.
It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.

Fact Box

Chemical Class

Progesterone Derivative

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Natural Progesterone

Interaction with drugs

Taking GEN with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Lenalidomide (Oral Route) Severe

Concurrent use may increase the risk of formation of blood clots. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observatio... More

Perampanel (Oral Route) Severe

Perampanel may reduce the efficacy of Progesterone. It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treat... More

Darunavir (Oral Route) Severe

If used together, Darunavir may affect blood levels of Progesterone. It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may m... More

Mycophenolate mofetil (Oral Route) Severe

Mycophenolate mofetil may reduce the efficacy of Progesterone. Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. ... More

Saquinavir (Oral Route) Severe

Concurrent use may result in contraceptive failure. It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treat... More

View all drug interactions

Patient concerns

Abdominal pain and vomiting sins 8 day

Dr. Rohan Bhatt

Dental Surgery

plz consult gen physicians

My left hand ring and center finger are always numb. I'm a nursing mother 5 months old There is some skin guilty type . I've attached it's pic.

Dr. Nabajit Talukdar

Cardiology

see a gen physician

I have severe body aches. I have white discharge during my regular days. Severe unbreakable joint pains. I had kidney stone problem i few months back. Head aches almost everyday. I also feel severe abdominal pain before and during intercourse. It is really unbreakable at times. I have never consulted a doctor or have done any medical tests. I few months back i had serious issues while consuming antibiotics and had to be hospitalised. This was may be 1 year ago. I really don't know what the symptoms are and whom i need to consult. Please urgent advice. Also to mention i am a pharmacist and do go through a lot of mental and physical stress due to work. And the pain and uneasiness is unbreakable today

Dr. Suman Rao

Obstetrics and Gynaecology

You should consult a physician as well as a gynae. Get your gen health check up done.

my mom got TSH 4.65 uIU/ml and BP 130/90 hg on dated we consulted doctor and got priscription Thyroup 50 mg for daily early morning on empty stomach. On next visit dated on TSH was 6.330 and BP 140/90 and also mild vertigo when get up in morning. After this doctor replaced Thyroup 50 to Thyroup 75 . After this my mom got BP up to 155/110 and getting vertigo continually day by day. I am feeling that Thyroup is giving side effect or it is not suitable for my mom. I am in worry please help.

Dr. Pushkar Mani

Physician

plz do following testfT3 fT4 TSH(3rd gen) , serum creatinine, HB1c, Blood sugar, lipid profile and urine routine

FAQs

Can you take GEN 400mg Soft Gelatin Capsule every day?

Yes, GEN 400mg Soft Gelatin Capsule can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor depending upon your health condition.

Does GEN 400mg Soft Gelatin Capsule cause weight gain?

Yes, taking GEN 400mg Soft Gelatin Capsule may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if GEN 400mg Soft Gelatin Capsule is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.

How is progesterone beneficial for fertility and pregnancy?

Progesterone is a very crucial hormone in fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. GEN 400mg Soft Gelatin Capsule (form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.

Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Testosterone Total

Thyroid Stimulating Hormone

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
Mayo Clinic. Progesterone. [Accessed 03 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
Progesterone [Prescribing Information]. St. Petersburg, FL: Catalent Pharma Solutions; 2009. [Accessed 28 Mar. 2023] (online) Available from:

Marketer details

Name: Feron Healthcare Pvt Ltd

Address: Feron Healthcare Private Limited., Shri Ven Ascot, Walker Town, Secunderabad – 500 025

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.