Gliclize 40 Tablet is a medicine used to treat type 2 diabetes mellitus in adults. It belongs to a group of medicines called sulfonylureas and helps control blood sugar levels in people with diabetes. This helps prevent serious complications of diabetes.

Gliclize 40 Tablet may be prescribed alone or along with other medicines. It should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you, which may change from time to time according to how it works. Continue using this medicine as prescribed, even if you feel fine or your blood sugar levels are stable. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, and nerve problems.

Keep in mind that this medicine is just one part of your treatment plan. It should be combined with a healthy diet, regular exercise, and weight management as recommended by your doctor. Your lifestyle plays a crucial role in managing diabetes.

The most common side effects of taking this medicine include diarrhea and headaches. It can also cause low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking. You must know how to deal with it.

To prevent hypoglycemic conditions, have regular meals and always carry a fast-acting source of glucose, such as sugary food or fruit juice, with you. Consuming alcohol can raise the risk of low blood sugar and should be avoided. Additionally, some individuals may experience weight gain while taking this medicine. You should not take Gliclize 40 Tablet if you have type 1 diabetes mellitus, diabetic ketoacidosis (high levels of acid in your blood), or severe kidney or liver disease.

Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Regularly monitor your blood sugar levels, and your doctor may recommend blood tests to check your blood cell counts and liver function.

Uses of Gliclize Tablet

Treatment of Type 2 diabetes mellitus

Benefits of Gliclize Tablet

In Treatment of Type 2 diabetes mellitus

Gliclize 40 Tablet is a medicine used for managing type 2 diabetes. It helps control blood sugar levels and reduces the risk of complications in patients with type 2 diabetes. Keeping blood sugar in balance supports overall health, improves energy levels, and helps prevent issues like nerve damage, kidney problems, and heart disease. It is beneficial to maintain a stable and active lifestyle while managing diabetes more effectively.

Side effects of Gliclize Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gliclize

Hypoglycemia (low blood glucose level)
Weight gain
Flatulence
Diarrhea
Headache
Nausea
Dizziness

How to use Gliclize Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gliclize 40 Tablet is to be taken with food.

How Gliclize Tablet works

Gliclize 40 Tablet is a diabetes medicine that helps lower blood sugar by increasing insulin release from the pancreas. It works by stimulating the pancreatic cells to produce more insulin, which helps move sugar from the blood into the cells for energy. It also helps the body use insulin more effectively and may support blood vessel health.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Gliclize 40 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Gliclize 40 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

UNSAFE

Gliclize 40 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Gliclize 40 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Gliclize 40 Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Gliclize 40 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Gliclize 40 Tablet may be needed. Please consult your doctor.

What if you forget to take Gliclize Tablet?

If you miss a dose of Gliclize 40 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Gliclize 40 Tablet

₹5.72/Tablet

Cyblex 40 Tablet

Eris Lifesciences Ltd

₹5.73/tablet

same price

Glizid 40 Tablet

Mankind Pharma Ltd

₹3.6/tablet

37% cheaper

Semi-Glycigon Tablet

Aristo Pharmaceuticals Pvt Ltd

₹5.69/tablet

1% cheaper

Glix 40 Tablet

Indi Pharma

₹5.7/tablet

same price

Euclide 40 Tablet

Alkem Laboratories Ltd

₹6.7/tablet

17% costlier

View all substitutes

Quick tips

Try to take it with the first main meal of the day (usually breakfast). Avoid skipping meals.
Be careful while driving or operating machinery until you know how Gliclize 40 Tablet affects you.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool, pale skin, tremors, and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Gliclize 40 Tablet helps decrease high blood sugar levels and avoid long-term complications of diabetes.

Fact Box

Chemical Class

Second-generation sulfonylurea derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Sulfonylureas (Insulin Secretagogues)

Interaction with drugs

Taking Gliclize with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Disopyramide (Oral Route) Severe

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them. Concurrent use m... More

Amisulpride (Oral Route) Moderate

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Amisulpride may reduce the efficacy of Gliclazi... More

Allopurinol (Oral Route) Moderate

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Concurrent use may cause low blood sugar levels.

Amiodarone (Oral Route) Moderate

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them. They may monitor ... More

Amiodarone (Injection Route) Moderate

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them. They may monitor ... More

View all drug interactions

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt

Physician

Go for allopathic medicine

Any latest discoveris for type 1 mellitus Diabetes?

Dr. Sanjay Bhatt

Physician

Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

How to manage diabetes mellitus

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Suffering from Diabetes mellitus since 7 years

Dr. Sanjay Bhatt

Physician

What is the best time to take Gliclize 40 Tablet?

Take Gliclize 40 Tablet with food or as instructed by your doctor. Take it once daily, and take it in the morning with breakfast, with a glass of water.

Is Gliclize 40 Tablet the same as metformin?

No, Gliclize 40 Tablet is not the same as metformin. Although both these oral medicines are used in the treatment of type 2 diabetes, the way they work to reduce sugar levels is different. While Gliclize 40 Tablet acts by increasing the secretion of insulin by the pancreas, metformin acts by improving the functioning and effectiveness of the insulin already available in the body.

Can you take metformin and Gliclize 40 Tablet at the same time?

Yes, Gliclize 40 Tablet and metformin can be taken at the same time, but only if prescribed by the doctor. Your doctor may have prescribed taking the two together to control your uncontrolled sugar levels. However, taking the two together may cause low blood sugar, which may also occur if you delay or miss a meal, exercise more than usual, or take it with insulin. Follow the instructions given by your doctor strictly to avoid such complications.

Is Gliclize 40 Tablet bad for kidneys?

No, Gliclize 40 Tablet is not harmful if your kidney function is normal. Any previous case of kidney problems should be reported to the doctor so that the use of Gliclize 40 Tablet can be assessed. This is done to analyze whether Gliclize 40 Tablet can be given or not, because it is principally excreted by the kidneys. If you have kidney problems, you will be started on a lower dose.

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

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References

Gliclazide [Product Monograph]. Brampton, Ontario: Sanis Health Inc.; 2017. [Accessed 23 Sept. 2021] (online) Available from:
Gliclazide [Product Monograph]. Solan, Himachal Pradesh: Panacea Biotec Limited; 2019. [Accessed 28 June 2023]. (online) Available from:
National Health Services. How and when to take gliclazide. [Last reviewed: 24 Mar. 2022]. [Accessed 28 June 2023]. (online) Available from:
Gliclazide [Product Monograph]. Cremorne, Australia: Arrotex Pharmaceuticals Pty Ltd; 2023. [Accessed 26 Feb 2025]. (online) Available from:

Marketer details

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Country of origin: India

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