Glofen 400mg/325mg Tablet contains two painkiller medicines. They work together to reduce pain, fever, and inflammation. It is used to treat many conditions such as headache, muscle pain, pain during periods, toothache, and joint pain.

Glofen 400mg/325mg Tablet is best taken with food to reduce side effects. The dose and how often you need it will be decided by your doctor. You should take it regularly as advised by your doctor. Medicines used to treat pain are usually best taken at the first sign of pain. It is meant for short-term use only. Consult your doctor if the symptoms persist or worsen or if the medicine is required for use beyond 3 days.

Side effects are rare if this medicine is used correctly but it may cause heartburn, indigestion, nausea, vomiting, headache, and stomach pain. Consult your doctor if any of these bother you or do not go away.

This medicine is widely prescribed and considered safe but may not be suitable for everybody. Before taking it, let your doctor know if you drink a lot of alcohol, are using blood-thinning medicines, or have asthma or any liver or kidney problems. It may affect the dose or suitability of this medicine. Pregnant or breastfeeding women should also consult their doctor before using it. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. It is best to avoid drinking alcohol while using this medicine.

Uses of Glofen Tablet

Benefits of Glofen Tablet

In Pain relief

Glofen 400mg/325mg Tablet contains two medicines: Paracetamol and Ibuprofen both of which are widely used as pain killers. They work in different ways to reduce pain, swelling, and inflammation. This medicine is very effective in treating mild to moderate pain associated with migraine, headache, backache, period (menstrual) pain, dental pain, and rheumatic and muscular pain. The anti-inflammatory component makes this medicine more effective in treating strains, sprains, and muscle pains.

Take it as it is prescribed to get the most benefit. Do not take too much as this can be dangerous and do not take it for longer than you need it. In general, you should take the lowest dose that works, for the shortest possible time.

In Treatment of Fever

Glofen 400mg/325mg Tablet helps lower high temperature caused by fever. This medicine is effective in treating cold and flu symptoms, sore throat, and fever. Take it as it is prescribed to get the most benefit. Do not take too much or for longer than you need as this can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

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Side effects of Glofen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Glofen

Heartburn
Indigestion
Nausea
Stomach pain
Vomiting
Headache
Sleepiness

How to use Glofen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glofen 400mg/325mg Tablet is to be taken with food.

How Glofen Tablet works

Glofen 400mg/325mg Tablet is a combination of two medicines: Ibuprofen and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Glofen 400mg/325mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Glofen 400mg/325mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Glofen 400mg/325mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Glofen 400mg/325mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Glofen 400mg/325mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glofen 400mg/325mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Glofen 400mg/325mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Glofen 400mg/325mg Tablet may be needed. Please consult your doctor.
However, the use of Glofen 400mg/325mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Glofen Tablet?

If you miss a dose of Glofen 400mg/325mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Glofen 400mg/325mg Tablet

₹2.0/Tablet

Ibugesic Plus Tablet

Cipla Ltd

₹1.76/tablet

12% cheaper

Brustan 400mg/325mg Tablet

Sun Pharmaceutical Industries Ltd

₹1.6/tablet

20% cheaper

Combiflam Tablet

Sanofi India Ltd

₹2.79/tablet

40% costlier

Flexon Tablet

Aristo Pharmaceuticals Pvt Ltd

₹2.21/tablet

10% costlier

Fenceta 400mg/325mg Tablet

Alkem Laboratories Ltd

₹2.14/tablet

7% costlier

View all substitutes

Quick tips

You have been prescribed this combination medicine to relieve pain, inflammation, and fever.
Take it with food to avoid getting an upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long-term use may lead to stomach bleeding and kidney problems.
Avoid consuming alcohol when taking Glofen 400mg/325mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough and cold) without asking your doctor first.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

Diagnosed with viral fever along with rashes on the body. Pain in eyes since three days. Pain when open and when blinking.

Dr. Richa Jain

Ophthalmology

Orbital pain is common with viral fever. Go to physician for fever. It will be relieved with relief in fever

FAQs

Is it safe to use Glofen 400mg/325mg Tablet?

Glofen 400mg/325mg Tablet is safe for most patients. However, in some patients, it may cause some unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor if you experience any persistent problem due to this medication.

Can I stop taking Glofen 400mg/325mg Tablet when my pain is relieved?

Glofen 400mg/325mg Tablet should be continued as advised by your doctor, if you are using the medicine for a condition associated with long-term pain. It can be discontinued if you are using it for short-term pain relief.

Can the use of Glofen 400mg/325mg Tablet cause nausea and vomiting?

Yes, the use of Glofen 400mg/325mg Tablet may cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine or a low frequency of urination. Do not take any other medicines without speaking to your doctor.

Can the use of Glofen 400mg/325mg Tablet cause dizziness?

Yes, the use of Glofen 400mg/325mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for sometime and resume once you feel better.

Are there any specific contraindications associated with the use of Glofen 400mg/325mg Tablet?

The use of Glofen 400mg/325mg Tablet is considered to be harmful for patients with known allergy to any of the components of this medicine. It should be avoided in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active or recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.

Is Glofen 400mg/325mg Tablet helpful in relieving stomach pain?

No, Glofen 400mg/325mg Tablet should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

Can the use of Glofen 400mg/325mg Tablet cause damage to kidneys?

Yes, the long-term use of Glofen 400mg/325mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lowers the levels of prostaglandins in the body, leading to kidney damage because of long-term use. Therefore, the use of painkillers is not recommended in patients with underlying kidney disease.

Is it safe to take a higher than the recommended dose of Glofen 400mg/325mg Tablet ?

No, taking a higher than the recommended dose of Glofen 400mg/325mg Tablet can increase the risks of side effects like nausea, vomiting, heartburn, indigestion and diarrhea. In fact, using this medicine for a long-term can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

ScienceDirect. Paracetamol/Acetaminophen. [Accessed 23 Apr. 2019] (online) Available from:
Acetaminophen and ibuprofen [Prescribing Information]. Greenville, NC: Catalent Greenville Inc.; 2023. [Accessed 14 Aug. 2024] (online) Available from:

Marketer details

Name: Globela Pharma Pvt Ltd

Address: 357, G.I.D.C. Road No.3,Sachin, Surat - 394 230 ,Gujarat, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.