Glyphase 1 Tablet
Prescription Required
Product introduction
Glyphase 1 Tablet belongs to a group of medicines called sulfonylureas and is used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes thereby preventing serious complications of diabetes such as kidney damage and blindness.
Glyphase 1 Tablet may be used alone or along with other medicines. It should be taken just before or with the first meal of the day. Take it regularly at the same time each day to get the maximum benefit. Your doctor will decide what dose is best for you and this may change from time to time according to your blood sugar levels.
Keep taking Glyphase 1 Tablet, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise to put you at risk of diabetes complications such as kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.
The most common side effects of taking Glyphase 1 Tablet include low blood sugar levels (hypoglycemia), nausea, headache, weakness, and dizziness. Make sure you recognize the signs of having low blood sugar levels, such as sweating, dizziness, headache, and shaking, and know how to deal with them. To prevent this, it is important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and hence should be avoided. Some people may experience an increase in weight with this medicine.
You should not take Glyphase 1 Tablet if you have type 1 diabetes mellitus, diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions, as it may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.
Uses of Glyphase Tablet
Side effects of Glyphase Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Glyphase
- Hypoglycemia (low blood glucose level)
- Headache
- Nausea
- Dizziness
- Weakness
How to use Glyphase Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glyphase 1 Tablet is to be taken with food.
How Glyphase Tablet works
Glyphase 1 Tablet is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Glyphase 1 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Glyphase 1 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Glyphase 1 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Glyphase 1 Tablet
Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Glyphase 1 Tablet
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Glyphase 1 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glyphase 1 Tablet may be needed. Please consult your doctor.
Use of Glyphase 1 Tablet is not recommended in patients with severe kidney disease. These patients can experience very low blood sugar levels which may become normal after a long time.
Use of Glyphase 1 Tablet is not recommended in patients with severe kidney disease. These patients can experience very low blood sugar levels which may become normal after a long time.
Liver
CAUTION
Glyphase 1 Tablet should be used with caution in patients with liver disease. Dose adjustment of Glyphase 1 Tablet may be needed. Please consult your doctor.
However, the use of Glyphase 1 Tablet is not recommended in patients with severe liver disease. These patients can experience very low blood sugar levels which may become normal after a long time.
However, the use of Glyphase 1 Tablet is not recommended in patients with severe liver disease. These patients can experience very low blood sugar levels which may become normal after a long time.
What if you forget to take Glyphase Tablet?
If you missed a a dose of Glyphase 1 Tablet, skip the missed dose and take your next dose at the usual time.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Take Glyphase 1 Tablet shortly before or with the first main meal of the day (usually breakfast).
- Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
- Monitor your blood sugar level regularly while you are taking Glyphase 1 Tablet.
- Glyphase 1 Tablet can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
- Be careful while driving or operating machinery until you know how Glyphase 1 Tablet affects you.
- Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
- Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Fact Box
Chemical Class
Third-generation Sulfonylurea Derivative
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Action Class
Sulfonylureas (Insulin Secretagogues)
Interaction with drugs
Taking Glyphase with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of low blood sugar levels. Elderly, malnourished, diabetic individuals and those with kidney and heart dysfunction are at higher risk.
If conc
Amiodarone may raise blood levels of Glimepiride.
If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult yo
Amisulpride may reduce the efficacy of Glimepiride.
If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observat
Amisulpride may reduce the efficacy of Glimepiride.
If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observat
Amiodarone may raise blood levels of Glimepiride.
If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult yo
Patient concerns
FAQs
What is the dosage of Glyphase 1 Tablet?
The recommended starting dose of Glyphase 1 Tablet is 1 mg or 2 mg once daily, administered with breakfast. If you are at a higher risk of low blood sugar (e.g., the elderly or patients with renal impairment), you will be given a starting dose of 1 mg once daily. The usual maintenance dose is 1–4 mg once daily. The maximum recommended dose is 8 mg once daily. After reaching a daily dose of 2 mg, the dosage will be increased not more than 2 mg at 1- to 2-week intervals, based on your blood glucose level.
Does Glyphase 1 Tablet make you sleepy?
Glyphase 1 Tablet itself does not cause sleepiness. However, it may cause hypoglycemia (low blood sugar) when used with other anti-diabetes medicine. Because of this you may feel sleepy or have problems in sleeping.
Is Glyphase 1 Tablet safe for kidneys?
Glyphase 1 Tablet does not affect kidneys in patients with normal kidney function. However, its use should be avoided in patients with severe kidney disease since Glyphase 1 Tablet is principally eliminated by the kidneys.
Does Glyphase 1 Tablet cause memory loss?
No, it is not known that Glyphase 1 Tablet causes memory loss. However, the use of Glyphase 1 Tablet may cause low blood sugar which may cause problems with concentration and reduced alertness.
Who should not take Glyphase 1 Tablet?
Glyphase 1 Tablet should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells) or are due to have surgery. Additionally, patients who are trying to get pregnant, are pregnant or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should avoid taking Glyphase 1 Tablet.
How long does it take for Glyphase 1 Tablet to start working?
Glyphase 1 Tablet takes about 2 to 3 hours to reduce blood sugar levels. You may not feel any difference, but this does not mean the medicine is not working. Continue taking the medication as directed by your doctor and if you have any concerns, discuss it with your doctor.
How long do I need to take Glyphase 1 Tablet? Can I stop the medication?
Usually, the treatment for diabetes is suggested for a long term. You may have to continue the treatment life long. Glyphase 1 Tablet only controls the sugar levels but does not cure it. Do not stop taking Glyphase 1 Tablet without talking to your doctor. If you stop taking Glyphase 1 Tablet suddenly your diabetes may get worse.
What can happen if I take more than the recommended dose of Glyphase 1 Tablet?
Glyphase 1 Tablet should be taken strictly as advised by the doctor. Overdose of Glyphase 1 Tablet may significantly decrease your blood sugar levels (hypoglycemia). If you think you have taken an excess dose and experience a dip in your sugar level, consume enough sugar (e.g., a small bar of sugar cubes, sweet juice or sweetened tea) and inform a doctor immediately. Severe cases of hypoglycemia accompanied by loss of consciousness and coma require immediate medical treatment and admission into hospital.
Can you take Glyphase 1 Tablet on an empty stomach?
No. Taking Glyphase 1 Tablet on an empty stomach can cause your blood sugar levels to become too low. Low blood sugar can cause dizziness, shaking, anxiety, irritability, a fast heartbeat, and confusion. Therefore, you should always take the medicine with breakfast or the first meal of the day. If you are skipping your meal, then you should also avoid taking Glyphase 1 Tablet.
Can Glyphase 1 Tablet cause weight gain?
Yes, Glyphase 1 Tablet can cause weight gain. Glyphase 1 Tablet is a sulfonylurea drug and causes the pancreas to release insulin. It may stimulate hunger and cause mild weight gain in some people. Patients are advised to eat a healthy balanced diet and exercise regularly to keep their weight stable.
Can Glyphase 1 Tablet cause dizziness?
Yes, Glyphase 1 Tablet can cause dizziness as a side effect. If this happens to you, sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while travelling.
What should you not eat while taking Glyphase 1 Tablet?
It is advisable to avoid foods that are high in saturated and trans fats, instead consume fats from fish and nuts. Control your carbohydrate intake as this directly affects your blood sugar.
Is Glyphase 1 Tablet safe to use?
Yes, Glyphase 1 Tablet tablet is safe when used as directed by the doctor. However, it may show some side effects. For best results, it should be used in the correct dose and at the same time each day.
Can people with diabetes have proteins?
Yes, people with diabetes must include proteins along with other essential nutrients in their daily diet. Proteins are one of the major energy providers among all essential nutrients. Besides, being the building blocks of the human body, proteins break down into glucose to release energy. Unlike carbohydrates, the metabolism of proteins into glucose is much slower. Therefore, the release of energy usually takes a few hours after consumption. Thus, the spike in blood sugar levels might occur after a few hours when you are on a high-protein diet.
Are artificial sweeteners good for people with diabetes?
No, artificial sweeteners are not good for people with diabetes. They are composed of chemicals that can cause mild to severe side effects. Thus, it is better to limit or avoid their use as much as you can.
Can diabetes cause kidney failure?
Yes, uncontrolled diabetes can cause kidney failure. In the long run, diabetes can affect the kidneys leading to a condition called diabetic nephropathy. Diabetic nephropathy is a condition that is a major cause of kidney failure in patients with diabetes. The best way to prevent damage to kidneys is by keeping diabetes in check, making dietary changes, monitoring sugar levels regularly, getting routine blood tests done, and taking prescribed medications on time.
Can diabetes be cured?
Diabetes is a condition that causes changes in your blood glucose levels, which if left uncontrolled, can lead to serious health complications affecting the heart, brain, kidneys, and eyes. However, with simple lifestyle changes, diet, and medications, one can manage their condition and lead a healthy life.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1255-1257.
- Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 740.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 629-30.
- Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 13 Mar. 2019] (online) Available from:
- DailyMed. Glimepiride [Drug Label Information]. [Accessed 20 Sept. 2021] (online) Available from:
- National Health Services. How and when to take glimepiride. [Last reviewed: 14 Mar. 2022]. [Accessed 28 June 2023]. (online) Available from:
Marketer details
Name: Griffins Life Sciences Pvt. Ltd
Address: A/302, Plot No.233, Sector 10, Kopra , Kharghar, Navi Mumbai- 410210 (MH), Mob- 9457322528
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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