Glyzest-M 2 Forte Tablet ER belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Glyzest-M 2 Forte Tablet ER should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Glyzest-M 2 Forte Tablet ER is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking, and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Glyzest-M Tablet ER

Treatment of Type 2 diabetes mellitus

Benefits of Glyzest-M Tablet ER

In Treatment of Type 2 diabetes mellitus

Glyzest-M 2 Forte Tablet ER is a combination medicine that increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Glyzest-M Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Glyzest-M

Headache
Hypoglycemia (low blood glucose level)
Nausea
Diarrhea

How to use Glyzest-M Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glyzest-M 2 Forte Tablet ER is to be taken with food.

How Glyzest-M Tablet ER works

Glyzest-M 2 Forte Tablet ER is a combination of two antidiabetic medicines: Glimepiride and Metformin.Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Glyzest-M 2 Forte Tablet ER.

Pregnancy

CONSULT YOUR DOCTOR

Glyzest-M 2 Forte Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

UNSAFE

Glyzest-M 2 Forte Tablet ER is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Glyzest-M 2 Forte Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Glyzest-M 2 Forte Tablet ER may be needed. Please consult your doctor.
Use of Glyzest-M 2 Forte Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

CAUTION

Glyzest-M 2 Forte Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Glyzest-M 2 Forte Tablet ER may be needed. Please consult your doctor.
Glyzest-M 2 Forte Tablet ER is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

What if you forget to take Glyzest-M Tablet ER?

If you miss a dose of Glyzest-M 2 Forte Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Glyzest-M 2 Forte Tablet ER

₹7.85/Tablet ER

Glopride M 2mg/1000mg Tablet ER

Globela Pharma Pvt Ltd

₹8.05/tablet er

3% costlier

Glims-G2 Forte Tablet ER

Dynamed Pharmaceuticals Pvt Ltd

₹8.3/tablet er

6% costlier

Glimilife M Forte 2mg/1000mg Tablet ER

MSN Laboratories

₹8.53/tablet er

9% costlier

Insu-GM (ER) Tablet

Olens Healthcare Pvt Ltd

₹8.73/tablet er

11% costlier

Glimerit-Forte Tablet ER

Dr. Ethix's Product & Services Pvt Ltd

₹4.23/tablet er

46% cheaper

View all substitutes

Quick tips

You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Glyzest-M 2 Forte Tablet ER.
Take it with food to lower your chance of having an upset stomach.
Monitor your blood sugar level regularly while you are taking this medicine.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glyzest-M 2 Forte Tablet ER may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Patient concerns

I am suffering from type 2 diabetes my current sugar level BSF 166 and PP 225 currently i take amryl m forte 1 tablet once daily

Dr. Sanjay Bhatt

Physician

It is not good control.A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

FAQs

Q. What are the recommended storage conditions for Glyzest-M 2 Forte Tablet ER?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Glyzest-M 2 Forte Tablet ER lead to lactic acidosis?

Yes, the use of Glyzest-M 2 Forte Tablet ER can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glyzest-M 2 Forte Tablet ER and consult your doctor immediately.

Q. What is Glyzest-M 2 Forte Tablet ER?

Glyzest-M 2 Forte Tablet ER is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Q. What are the possible side effects of Glyzest-M 2 Forte Tablet ER?

The use of Glyzest-M 2 Forte Tablet ER is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.

Q. Can the use of Glyzest-M 2 Forte Tablet ER lead to Vitamin B12 deficiency?

Yes, the use of Glyzest-M 2 Forte Tablet ER can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Can the use of Glyzest-M 2 Forte Tablet ER cause hypoglycemia?

Yes, the use of Glyzest-M 2 Forte Tablet ER can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Q. Is it safe to take alcohol while I am also taking Glyzest-M 2 Forte Tablet ER?

No, it is not safe to take Glyzest-M 2 Forte Tablet ER along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.

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Glucose - Postprandial Blood

Glycosylated Hemoglobin

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References

Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 08 Apr. 2019] (online) Available from:
Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:
American Diabetes Association. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2020. Diabetes Care. 2020;43(Suppl 1): S98-S110. [Accessed 28 Oct. 2021] (online) Available from:
Glimepiride and Metformin Hydrochloride Sustained Release [Patient Information Sheet]. Ahmedabad, Gujarat: TORRENT PHARMACEUTICALS LTD.; 2016. [Accessed 28th Sept. 2023] (online) Available from:

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