Graine 5mg Tablet is a medicine used for the prevention of migraines. However, it cannot treat an acute attack and will only work to prevent migraines for as long as you continue to take the medicine. This medicine relaxes the brain, preventing migraine headaches.

Graine 5mg Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better and if you have missed a dose, take it as soon as you remember. You should continue to take this medicine for as long as the doctor advises and do not stop taking it suddenly.

Side effects associated with the use of this medicine include muscle pain, fatigue, constipation, nausea, insomnia (difficulty sleeping), and runny nose. Some other side effects that may be seen on taking this medicine are increased appetite, depression, stomach discomfort, and breast pain. It may also cause sleepiness at the beginning of your treatment, so do not drive, operate machinery, until you know how this medicine affects you.

It may also cause weight gain and to prevent it you can eat a healthy balanced diet and should exercise regularly. This medicine may cause changes in your mood and you may feel depressed, therefore, regular monitoring of behavior is important. Pregnant or breastfeeding mothers should consult their doctor before taking this medicine.

Uses of Graine Tablet

Migraine

Side effects of Graine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Graine

Sleepiness
Weight gain
Muscle pain
Fatigue
Constipation
Nausea
Insomnia (difficulty in sleeping)
Runny nose
Increased appetite
Depression
Stomach discomfort
Breast pain

How to use Graine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Graine 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Graine Tablet works

Migraine headaches are thought to result from the dilatation of blood vessels in the head. Graine 5mg Tablet works by preventing loss of tone and dilation of blood vessels, thus preventing the migraine headache.

Safety advice

Alcohol

UNSAFE

Graine 5mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Graine 5mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Graine 5mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Graine 5mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Graine 5mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Graine 5mg Tablet may not be needed in these patients. Please consult your doctor.
However, consult your doctor if have severe kidney disease.

Liver

CAUTION

Graine 5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Graine 5mg Tablet may be needed. Please consult your doctor.

What if you forget to take Graine Tablet?

If you miss a dose of Graine 5mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Graine 5mg Tablet

₹2.62/Tablet

Flunarin 5 Tablet

FDC Ltd

₹2.7/tablet

3% costlier

Fluner 5 Tablet

Geno Pharmaceuticals Ltd

₹2.4/tablet

8% cheaper

Migranex 5 Tablet

Intas Pharmaceuticals Ltd

₹2.7/tablet

3% costlier

Migarid 5 Tablet

Cipla Ltd

₹2.3/tablet

12% cheaper

Grenil-F 5mg Tablet

Karnataka Antibiotics & Pharmaceuticals Ltd

₹1.9/tablet

27% cheaper

View all substitutes

Quick tips

You have been prescribed Graine 5mg Tablet for the prevention of migraine headaches.
Do not take it to treat an acute attack of migraine.
Some tips that may help avoid a migraine attack:
- Have your meals at the same time every day
- Avoid bright lights and extreme temperatures
- Avoid loud music and noisy places
- Avoid chocolates, cheese, processed food, alcohol and smoking
- Get sufficient sleep and avoid stress
It should be taken at night-time before going to bed.
It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how Graine 5mg Tablet affects you.
Notify your doctor if you develop skin rash, muscle aches, tremors, difficulty moving, or abnormal uncontrolled movement.

Fact Box

Chemical Class

Diphenylmethanes Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Calcium Channel Blockers (CCBs)- Migraine Prevention

Interaction with drugs

Taking Graine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Tramadol (Oral Route) Moderate

Concurrent use may increase sleepiness and drowsiness. Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.

Alprazolam (Injection Route) Moderate

Concurrent use may cause increased sedation. Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.

Alprazolam (Oral Route) Moderate

Concurrent use may cause increased sedation. Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.

Clonazepam (Injection Route) Moderate

Concurrent use may cause increased sedation. Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.

Chlordiazepoxide (Oral Route) Moderate

Concurrent use may cause increased sedation. Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.

View all drug interactions

Patient concerns

I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)

Dr. Faran Siddiqui

Homeopathy

Migraine and headache are two different things migraine is primarily headache of one side in symmetrically

Some time at a sudden Strong half headache pain in left side and also left eye tearing Please consult me

Dr. Pushkar Mani

Physician

it could be migraine

FAQs

Is Graine 5mg Tablet safe?

Graine 5mg Tablet is safe if used at prescribed doses for the prescribed duration as advised by the doctor.

What is Graine 5mg Tablet used for?

Graine 5mg Tablet is a calcium channel blocker and is used to prevent migraine attacks. Migraine is a recurrent throbbing headache that typically affects one side of the head and is often accompanied by nausea and disturbed vision.

Does Graine 5mg Tablet cause weight gain?

Graine 5mg Tablet can cause weight gain. It is caused by an increase in appetite (feeling hungry) and can be avoided by keeping to your usual diet. Please consult your doctor if you experience weight gain after taking Graine 5mg Tablet.

Does Graine 5mg Tablet work?

Graine 5mg Tablet works if used at prescribed doses for the prescribed duration as advised by your doctor.

Top Physicians

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MBBS, MD, Fellowship, Fellowship, Fellowship

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 283.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Flunarizine [Package Leaflet]. County Cork, Ireland: Janssen Sciences Ireland UC; 2020. [Accessed 25 Jul. 2024] (online) Available from:

Marketer details

Name: Ceras Pharmaceutical

Address: No 21 Parkavi Apartments, Mariamman Koil Street, K K Nagar West, Chennai - 600078

Country of origin: India

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