Author Details
Written By
MMST, MBBS
Reviewed By
MD Pharmacology, MBBS
Last updated
17 Dec 2024 | 01:01 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Grandem 1 Tablet

Prescription Required
arrow
arrow

Product introduction

Grandem 1 Tablet is an antiemetic medicine commonly used to control nausea and vomiting caused due to any surgery, cancer drug therapy, or radiotherapy.

Grandem 1 Tablet will not relieve other side effects associated with cancer treatments. It also has little effect on vomiting caused by motion sickness. You should take this medicine in the dose and duration advised by your doctor. But, it is better to take this medicine at a fixed time. Remember, you should not stop taking this medicine suddenly without talking to your doctor. In case you vomit within one hour of taking a dose, then take another dose and avoid heavy meals throughout the day.

The most common side effects of taking this medicine include headache, constipation, diarrhea, and weakness. Dizziness and sleepiness may also occur, so do not drive or do anything that requires mental focus until you know how this medicine affects you. These symptoms should disappear when you stop taking the medicine but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicine that you might be using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your healthcare team.

Uses of Grandem Tablet

Benefits of Grandem Tablet

In Nausea and vomiting due to chemotherapy

Grandem 1 Tablet is used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. It blocks the action of chemicals in the body that can make you feel or be sick. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy.

Side effects of Grandem Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Grandem

  • Weakness
  • Headache
  • Constipation
  • Diarrhea
  • Insomnia (difficulty in sleeping)

How to use Grandem Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Grandem 1 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Grandem Tablet works

Grandem 1 Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Grandem 1 Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Grandem 1 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Grandem 1 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Grandem 1 Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Grandem 1 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Grandem 1 Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Grandem 1 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Grandem 1 Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Grandem Tablet?

If you miss a dose of Grandem 1 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Grandem 1 Tablet
₹10.5/Tablet
Grantis 1mg Tablet
Atlantis Formulations Pvt Ltd
₹7.43/tablet
29% cheaper
Graniset 1 Tablet
Sun Pharmaceutical Industries Ltd
₹27.75/tablet
164% costlier
Graniforce 1mg Tablet
Mankind Pharma Ltd
₹5.99/tablet
43% cheaper
Granexa 1mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹4/tablet
62% cheaper
Cadigran 1mg Tablet
Cadila Pharmaceuticals Ltd
₹21.38/tablet
104% costlier

Quick tips

  • You have been prescribed Grandem 1 Tablet for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
  • It is fast-acting and starts working within 30 minutes.
  • If you vomit within one hour of taking a dose, take another dose.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Fact Box

Chemical Class
Indazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin 5-HT3 Receptor Antagonists

Interaction with drugs

Taking Grandem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may disturb the heart rhythm. Do not consume Apomorphine with Granisetron. If concurrent use is essential, please consult your doctor.
Concurrent use may disturb the heart rhythm. Do not consume Apomorphine with Granisetron. If concurrent use is essential, please consult your doctor.
Concurrent use may cause serotonin syndrome. watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Factors such as o... More
Concurrent use may disturb the heart rhythm. Careful consideration is advised when taking Levofloxacin with Granisetron. Your doctor may monitor your treatment and adjust the dose... More
Concurrent use may disturb the heart rhythm. Careful consideration is advised when taking Ciprofloxacin with Granisetron. Your doctor may monitor your treatment and adjust the dos... More

Patient concerns

arrow
Vomiting, nausea neck pain backside
Dr. Vijay Verma
ENT
Neck pain may be due to nausea NAD vomiting Visit physician for the same
NAUSEA AND VOMITING DUE TO COLD
Dr. Sunil Sekhri
Diabetology
Tab Domstal 1 tab Stat and keep yourself warm
arrow

FAQs

What is Grandem 1 Tablet used for?

Grandem 1 Tablet is an antiemetic medicine used to treat and prevent nausea or vomiting caused after any surgical procedure or due to certain medicines, stomach upset, or cancer treatment. It also prevents nausea due to motion sickness to some extent.

What are the side effects of Grandem 1 Tablet?

The most common side effects of Grandem 1 Tablet are sleepiness, weakness, headache, constipation and diarrhea. However, these are not usually bothersome and resolve in some time on their own. Consult your doctor, if the symptoms worry you or persist for a longer duration. Your doctor will suggest ways to cope up with these side effects and to prevent them in future.

Is Grandem 1 Tablet safe to be used in pregnant women?

Grandem 1 Tablet did not show any adverse effects in research studies done on animals. However, since the safety and efficiency of Grandem 1 Tablet in pregnant women is unknown. It is not recommended to be used in women who are pregnant women or if you are planning to conceive unless prescribed by your doctor.

Is Grandem 1 Tablet better than Ondansetron?

Grandem 1 Tablet and Ondansetron belong to the same class of medicines, that is serotonin 5-HT3 receptor antagonists. Both these medicines help prevent nausea and vomiting effectively. However, some studies suggest that Grandem 1 Tablet is more effective than Ondansetron. According to some reports, Grandem 1 Tablet is comparatively well tolerated, quicker in action and alleviates nausea and vomiting relatively faster.

Does Grandem 1 Tablet cause constipation?

Yes, Grandem 1 Tablet may cause constipation as one of the common side effects. However, this is usually not bothersome. Taking a fiber-rich diet can enhance your digestion and avoid constipation. You may also consider taking laxatives for relief and drink plenty of water too. Avoid drinking alcohol as it may worsen your constipation. If you still face issues, please consult your doctor to know about ways to treat it.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Granisetron. Hertfordshire: Generics [UK] Limited; 2005 [revised Nov. 2018]. [Accessed on 28 Mar. 2018] (online) Available from:External Link
  2. Drugs.com. Granisetron Pregnancy and Breastfeeding Warnings. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Aristo Pharmaceuticals Pvt Ltd
Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Country of origin: India
Expires on or after: August, 2025

A licensed vendor partner from your nearest location will deliver Grandem 1 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

89.25105Get 15% OFF
80.85+ free shipping withCare Plan Logo
Inclusive of all taxes
This offer price is valid on orders above ₹1800. Apply coupon HEALTHALL on the cart. Max. coupon discount is ₹380. T&C apply.
10.0 tablets in 1 strip
Add to cart
Cash on delivery available
Get it delivered in 60 mins
Delivering to:
122019, GurgaonDown Arrow Icon

Additional offers

Airtel Payments Bank: Pay with Airtel Payments Bank and get 10% cashback up to Rs. 200 cashback on a minimum transaction of ₹1000. Valid only for first-time users for Airtel Payments Bank Savings Bank accounts.
Show more show_more

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.