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MS, BDS
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MD Pharmacology, MBBS
Last updated
03 Nov 2024 | 01:08 AM (IST)

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Hepadot Injection

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Hepadot Injection is a medicine which is used in the treatment of heparin overdose. It neutralizes the anti-blood clotting effect of heparin and stops excessive bleeding.

Hepadot Injection is generally administered by a healthcare professional. You should not self administer this medicine. Inform your doctor if you have undergone heart surgery, have had a vasectomy, have diabetes, have received protamine insulin, or allergic to fish.

Using of Hepadot Injection can cause few side effects such as decreasing your blood pressure, slow heart rate, or reactions at the site of injection. It is important to monitor the clotting levels if you are receiving multiple doses or prolonged administration of protamine.

Uses of Hepadot Injection

  • Heparin overdose

Benefits of Hepadot Injection

In Heparin overdose

Heparin is an anticoagulant that prevents the formation of blood clots. Heparin overdose is when a person takes more than the normal or recommended amount of heparin. Hepadot Injection helps to control excessive bleeding that takes place due to this high intake of heparin. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully and let your doctor know about any surgeries you may have undergone in the past.

Side effects of Hepadot Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Hepadot

  • Decreased blood pressure
  • Slow heart rate
  • Injection site reactions (pain, swelling, redness)

How to use Hepadot Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Hepadot Injection works

Hepadot Injection is used to counteract the anticoagulant effect of heparin and is used to stop bleeding in patients caused by heparin.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Hepadot Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Hepadot Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Hepadot Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Hepadot Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Hepadot Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Hepadot Injection may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Hepadot Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Hepadot Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Hepadot Injection?

If you miss a dose of Hepadot Injection, please consult your doctor.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Hepadot Injection helps neutralize the effect of anti-clotting medicine heparin.
  • It should not be used to reverse the effects of other anti-clotting medicines (anticoagulants) such as warfarin.
  • It should be used under medical supervision. Do not self-administer.
  • Inform your doctor if you experience a sudden fall in blood pressure, breathlessness, or chest and abdominal pain when receiving Hepadot Injection.

Fact Box

Chemical Class
Blood Factor
Habit Forming
No
Therapeutic Class
OTHERS
Action Class
Heparin Antagonist

Patient concerns

arrow
I am not getting pregnant while dnc has done Because there was miscarriage 4 month back
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Low molecular weight heparin
Why low molecular weight heparin used in pregnancy
Dr. Suman Rao
Obstetrics and Gynaecology
It's used only in high risk pregnancy and in certain condition like APLA to prevent miscarriage
arrow

FAQs

Q. Is protamine sulphate the antidote for lovenox?

Yes. Protamine sulphate is used as an antidote in the case of overdose of lovenox.

Q. Is protamine an anticoagulant?

When administered alone, protamine has an anticoagulant effect. However, when it is given in the presence of heparin, a stable salt is formed and the anticoagulant activity of both drugs is lost

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1167-68.
  2. Medscape. Protamine. [Accessed 6 Apr. 2019] (online) Available from:External Link
  3. Protamine. Lake Zurich, Illinois: Fresenius Kabi; 2016. [Accessed 06 Apr. 2019] (online) Available from:External Link
  4. Howland MA. Antidotes in Depth. In: Hoffman RS, Howland MA, Lewin NA, et al., editors. Goldfrank's Toxicologic Emergencies. 10th ed. New York, New York: McGraw-Hill Education; 2015. [Accessed 30 Jan. 2019]. (online) Available from:External Link
  5. Protamine sulfate. Wrexham: Wockhardt UK Ltd.; 1991 [revised 4 May 2018]. [Accessed 6 Apr. 2019] (online) Available from:External Link
  6. Drugs.com. Protamine Pregnancy and Breastfeeding Warnings. [Accessed 6 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Biological E Ltd
Address: Biological E. Limited, Road No. 35,Jubilee Hills, Hyderabad, Telangana -500033

NOT FOR SALE
We do not facilitate sale of this product at present

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