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Imfinzi 500mg Injection

Prescription Required
Marketer
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Imfinzi 500mg Injection is an anticancer drug used to treat several cancers, including non-small cell lung cancer, biliary tract cancer, liver cancer, and endometrial cancer. It works by blocking the PD-L1 protein on cancer cells. This allows the immune system to recognize and attack these cells more effectively.

Imfinzi 500mg Injection is administered as an intravenous infusion, typically given in a hospital or a clinical setting. Make sure to attend all scheduled appointments and follow your doctor’s instructions. Maintaining a healthy lifestyle, including a balanced diet and regular exercise, can help optimize the treatment's effectiveness.


Common side effects include fatigue, cough, nausea, and loss of appetite. Some patients may experience diarrhea, skin rash, or shortness of breath. If you experience severe or persistent side effects, contact your doctor immediately. Staying hydrated and reporting side effects early can help manage them effectively.


While on Imfinzi 500mg Injection, avoid activities that can increase your risk of infection, such as contact with sick individuals or large crowds. The drug can cause immune-related side effects, such as inflammation of the lungs, liver, or intestines, so report any unusual symptoms promptly.


Imfinzi 500mg Injection is not recommended for individuals with certain autoimmune conditions or those who are pregnant or breastfeeding, as it may pose risks to the fetus or infant. Before receiving this injection, inform your doctor about any other medications you are taking to avoid interactions. Always discuss your medical history and any concerns with your doctor before starting treatment.


Benefits of Imfinzi Injection

In Treatment of Non-small cell lung cancer

Imfinzi 500mg Injection enhances overall survival and progression-free survival by enabling the immune system to better recognize and attack cancer cells. Patients receiving Imfinzi 500mg Injection after chemoradiation therapy experience longer periods without disease progression compared to those not on the drug.

In Treatment of Liver cancer

In liver cancer, especially hepatocellular carcinoma, Imfinzi 500mg Injection offers benefits when combined with other treatments like bevacizumab. This combination improves overall survival and delays disease progression. This provides a valuable option for patients with advanced or unresectable liver cancer.

In Treatment of Endometrial cancer

For endometrial cancer, particularly in cases that are recurrent or have spread, Imfinzi 500mg Injection works by boosting the immune system’s ability to fight cancer cells. This leads to improved response rates. Additionally, it results in longer progression-free survival in patients who may have exhausted other treatment options.

In Treatment of Biliary tract cancer

Imfinzi 500mg Injection, when combined with chemotherapy, has been shown to extend survival in patients with advanced biliary tract cancer. The drug helps in shrinking tumors and delaying the progression of the disease, offering a new option for a cancer type that previously had limited effective treatments.

Side effects of Imfinzi Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Imfinzi

  • Cough
  • Nausea
  • Fatigue
  • Hair loss
  • Diarrhea
  • Pneumonitis
  • Breathlessness
  • Itching
  • Musculoskeletal (bone, muscle or joint) pain
  • Abdominal pain
  • Upper respiratory tract infection
  • Rash

How to use Imfinzi Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Imfinzi 500mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Imfinzi 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Imfinzi 500mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Imfinzi 500mg Injection may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Imfinzi 500mg Injection is safe to use in patients with kidney disease. No dose adjustment of Imfinzi 500mg Injection is recommended.
Liver
SAFE IF PRESCRIBED
Imfinzi 500mg Injection is safe to use in patients with liver disease. No dose adjustment of Imfinzi 500mg Injection is recommended.

What if you forget to take Imfinzi Injection?

If you miss a dose of Imfinzi 500mg Injection, contact your doctor as soon as possible. They will advise you on how to proceed, which may include rescheduling the missed dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • It is important to stick to your treatment schedule. If you miss a dose, contact your doctor immediately to reschedule.
  • Get regular check-ups and lab tests to track your response to the treatment and detect any potential issues early.
  • Drink plenty of fluids to manage some side effects like fatigue and dehydration.
  • Since Imfinzi 500mg Injection can weaken your immune system, avoid exposure to infections by practicing good hygiene and staying away from crowded places.
  • Be aware of serious side effects like difficulty breathing, severe abdominal pain, or jaundice. Seek medical attention immediately if these occur.

Fact Box

Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Monoclonal Antibodies (mAbs)

Patient concerns

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma
Dr. Vijay Sharnangat
Medical Oncology and Hematology
This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.
I want to know the symptoms of cancer as I am a smoker
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.

FAQs

What types of cancer does Imfinzi 500mg Injection treat?

Imfinzi 500mg Injection is used to treat non-small cell lung cancer (NSCLC), biliary tract cancer, liver cancer, and endometrial cancer. It's often prescribed when these cancers are advanced or unresectable.

How is Imfinzi 500mg Injection administered?

Imfinzi 500mg Injection is given as an intravenous (IV) infusion, typically in a hospital or clinic setting, under the supervision of a healthcare provider.

What should I expect during treatment with Imfinzi 500mg Injection?

You may experience side effects like fatigue, cough, or appetite loss. It's important to report any severe symptoms to your doctor right away.

Can I take Imfinzi 500mg Injection with other medications?

You should inform your doctor of all medications and supplements you are taking, as Imfinzi 500mg Injection can interact with other drugs.

What precautions should I take while on treatment with Imfinzi 500mg Injection?

Avoid exposure to infections, report any unusual symptoms, and discuss your medical history with your doctor, especially if you have autoimmune conditions, are pregnant, or breastfeeding.

How long will I need to be on Imfinzi 500mg Injection?

The duration of treatment with Imfinzi 500mg Injection depends on your specific cancer type, response to the treatment, and overall health. Your doctor will determine the best treatment plan for you.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. AstraZeneca. IMFINZI (durvalumab) [Product Information]. 2024. [Accessed 12 Aug. 2024] (online) Available from: External Link
  2. Durvalumab [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2024. [Accessed 12 Aug. 2024] (online) Available from: External Link
  3. Durvalumab for injection [Product Monograph]. Mississauga, Ontario: AstraZeneca Canada Inc.; 2024. [Accessed 12 Aug. 2024] (online) Available from: External Link

Marketer details

Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Country of origin: United kingdom
Expires on or after: June, 2025

A licensed vendor partner from your nearest location will deliver Imfinzi 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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10.0 ml in 1 vial
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