Irosus 20mg/37.5mg Tablet is used in the treatment of heart failure. It is a combination of two medicines that effectively control symptoms of heart failure.

Irosus 20mg/37.5mg Tablet should be taken with food regularly at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like a low-fat diet, exercise, and not smoking may help this medicine to work better.

It is generally safe and suitable for most people but has some potential side effects. The most common side effects of this medicine include nausea, vomiting, diarrhea, low blood pressure, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It makes you feel dizzy as of orthostatic hypotension (sudden lowering of blood pressure on standing). Hence, rise slowly while from a sitting position or avoid driving. You may be asked for regular monitoring of blood pressure while on the treatment.

Before taking this medicine, tell your doctor if you have liver or kidney disease. You must tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.

Uses of Irosus Tablet

Treatment of Heart failure

Benefits of Irosus Tablet

In Treatment of Heart failure

Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen and other parts of your body. Irosus 20mg/37.5mg Tablet makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.
This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes, such as eating healthy and keeping active, to help this medicine be effective. Take it regularly and keep taking it even if you feel better.

Side effects of Irosus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Irosus

Nausea
Headache
Dizziness
Weakness
Ventricular tachycardia
Paralysis of ileus
Hypotension (low blood pressure)
Visual impairment

How to use Irosus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Irosus 20mg/37.5mg Tablet is to be taken with food.

How Irosus Tablet works

Irosus 20mg/37.5mg Tablet is a combination of two medicines:.

Safety advice

Alcohol

UNSAFE

Consuming alcohol while taking Irosus 20mg/37.5mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy

CONSULT YOUR DOCTOR

Irosus 20mg/37.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Irosus 20mg/37.5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Irosus 20mg/37.5mg Tablet may cause side effects which could affect your ability to drive.
As Irosus 20mg/37.5mg Tablet may cause headaches or lead to difficulty in concentration and this may affect your ability to drive.

Kidney

CAUTION

Irosus 20mg/37.5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Irosus 20mg/37.5mg Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is recommended for better dose adjustment.

Liver

SAFE IF PRESCRIBED

Irosus 20mg/37.5mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Irosus 20mg/37.5mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Irosus Tablet?

If you miss a dose of Irosus 20mg/37.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Irosus 20mg/37.5mg Tablet

₹12.4/Tablet

Nitrohart Tablet

Mankind Pharma Ltd

₹8.58/tablet

31% cheaper

Apresol Plus Tablet

Ordain Health Care Global Pvt Ltd

₹11.07/tablet

11% cheaper

Isorus Tablet

Ajanta Pharma Ltd

₹13.07/tablet

5% costlier

Isolazine Tablet

Lupin Ltd

₹13.47/tablet

9% costlier

Isorus Tablet

Ajanta Pharma Ltd

₹8.39/tablet

32% cheaper

Quick tips

Irosus 20mg/37.5mg Tablet is a combination of two medicines that helps improve symptoms of heart failure and keeps your heart healthier.
This medicine may temporarily cause headaches, especially when starting treatment. Inform your doctor if it does not go away.
Irosus 20mg/37.5mg Tablet may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
It is best to avoid drinking alcohol while taking Irosus 20mg/37.5mg Tablet as it may make the side effects worse.
Do not take it in combination with medicines that treat erectile dysfunction (eg. sildenafil, tadalafil, vardenafil) or high blood pressure, as that can cause a major drop in blood pressure.
Do not stop taking Irosus 20mg/37.5mg Tablet suddenly without talking to your doctor as it can increase the risk of heart attack and stroke.

Fact Box

Habit Forming

Therapeutic Class

CARDIAC

Patient concerns

What is BNP test? Pls explain. What is BNP ASSAY?My result is133.0 explain

Dr. Manju Singh

Homeopathy

BNP levels below 100 pg/mL indicate no heart failure. BNP levels of 100-300 pg/mL suggest heart failure is present. BNP levels above 300 pg/mL indicate mild heart failure. BNP levels above 600 pg/mL indicate moderate heart failure.The level of BNP in the blood increases when heart failure symptoms worsen, and decreases when the heart failure condition is stable

Myself is high B.P patients .There is some swelling in the face today . what is going on?

Dr. Pushkar Mani

Physician

Kidney damage or heart failure

my mom heart ef is 35 she suffer congestive heart failure says heart rythum is not good aa result he suggest for pacemaker when she admit ef is 30 and after 10 days it shows 35 show it will increase naturally or use medicine life time any medicine in aurveda to live long and natural also suggeat intake only 2liter water a day please suggest me waiting for ur answer thanks

Dr. Deepak Kumar Soni

Ayurveda

Hi Need to consult to face to face kindly visit any ayurveda doctor at your city

What for Nefrosave tablet is recommended ???

Dr. Sanjay Bhatt

Physician

Nefrosave Tablet Uses Nefrosave Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: High Blood Pressure Join 148 Pro Subscribers Hereditary Disorder Affecting The Exocrine Glands Hepatitis Join 48 Pro Subscribers Carbon Tetrachloride Poisoning Join 75 Pro Subscribers Acute Bronchitis Join 74 Pro Subscribers Chronic Bronchitis Paracetamol Poisoning Congestive Heart Failure High Cholesterol

Hi! My diagnosed me with Tinea Cruris which is like a red patch between my thighs near my genitals so he recommended me ITRASYS-200 MG (Twice Daily) for 30 days and gave an ointment EBERNET-M. After taking them the Tinea was almost gone when suddenly I had a breakout again and it itches a lot. I would appreciate your opinion on this matter. Thanks! :) Also kindly let me know should I take the same again? Or maybe if you could be able to suggest something better?

Dr. Souvik Sardar

Dermatology

Apply ebernet cream not ebernet m Twice daily for 6wksStart itraconazole 200 mg - 1cap daily after lunch for 3wksTake itraconazole only if u dnt HV any heart problem like heart failure

FAQs

Can I stop taking Irosus 20mg/37.5mg Tablet if I feel well?

No, keep using Irosus 20mg/37.5mg Tablet as advised by your doctor, even if you feel well. Stopping Irosus 20mg/37.5mg Tablet suddenly may lead to serious complications of heart failure.

Are there any special instructions regarding storage and disposal of this medicine?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can the use of Irosus 20mg/37.5mg Tablet cause headache?

Irosus 20mg/37.5mg Tablet can frequently cause headaches, especially at the start of the treatment. As the treatment continues, your headache may become less intense and frequent. However, inform your doctor if headache continues.

Can the use of Irosus 20mg/37.5mg Tablet cause dizziness?

Yes, the use of Isosorbide Irosus 20mg/37.5mg Tablet can make you feel dizzy. This may often occur when you suddenly rise up from lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

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References

Ferdinand KC, Elkayam U, Mancini D, et al. Use of isosorbide dinitrate and hydralazine in African-Americans with heart failure 9 years after the African-American Heart Failure Trial. Am J Cardiol. 2014;114(1):151-9. [Accessed 21 Jan. 2019] (online) Available from:
Mastanamma SK, Saidulu P, Sravanthi A, et al. Stability Indicating Validated RP-HPLC Method for Simultaneous Determination of Hydralazine Hydrochloride and Isosorbide Dinitrate in Bulk and Pharmaceutical Dosage Form. Int J Pharm Sci Rev Res. 2016;40(1):1411-48. [Accessed 21 Jan. 2019] (online) Available from:
Cheng JW. A review of isosorbide dinitrate and hydralazine in the management of heart failure in black patients, with a focus on a new fixed-dose combination. Clin Ther. 2006;28(5):666-78. [Accessed 21 Jan. 2019] (online) Available from:
Isosorbide dinitrate and hydralazine hydrochloride. Seymour, Indiana: Kremers Urban Pharmaceuticals Inc.; 2005 [revised Apr. 2015]. [Accessed 23 Jan. 2019] (online) Available from:
Isosorbide dinitrate and hydralazine hydrochloride [Prescribing Inforamtion]. Seymour, IN: Kremers Urban Pharmaceuticals Inc.; 2015. [Accessed 28th Sept. 2023] (online) Available from:
Central Drugs Standard Control Organization. Isosorbide Dinitrate+Hydralazine. [Accessed 28th Sept. 2023] (online) Available from:
ScienceDirect. Isosorbide Dinitrate. [Accessed 28th Sept. 2023] (online) Available from:

Marketer details

Name: Colosiem Health Care Pvt Ltd

Address: Hyderabad, Telangana, India

Country of origin: India

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