Isentress 400mg Tablet
Prescription Required
Product introduction
Isentress 400mg Tablet is an antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It prevents the multiplication of viruses in human cells and clears up your infection.
Isentress 400mg Tablet is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow the instructions carefully, for all the medicines that you are given. It may be taken with or without food, preferably at a fixed time. Avoid taking antacids containing aluminum or magnesium within 2 hours before or 2 hours after you take this medicine. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.
Some of the common side effects include insomnia (difficulty sleeping), headache, nausea, dizziness, and muscle pain. These are usually not serious but tell your doctor if they bother you or persist for a longer duration. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.
Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.
Isentress 400mg Tablet is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow the instructions carefully, for all the medicines that you are given. It may be taken with or without food, preferably at a fixed time. Avoid taking antacids containing aluminum or magnesium within 2 hours before or 2 hours after you take this medicine. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.
Some of the common side effects include insomnia (difficulty sleeping), headache, nausea, dizziness, and muscle pain. These are usually not serious but tell your doctor if they bother you or persist for a longer duration. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.
Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.
Uses of Isentress Tablet
Benefits of Isentress Tablet
In HIV infection
Isentress 400mg Tablet prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life. This medicine is always taken in combination with other antiretroviral medicines.
It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.
It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.
Side effects of Isentress Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Isentress
- Diarrhea
- Dizziness
- Fatigue
- Headache
- Insomnia (difficulty in sleeping)
- Nausea
- Abdominal pain
- Abnormal dreams
- Decreased appetite
- Depression
- Flatulence
- Nightmares
- Vomiting
- Weakness
How to use Isentress Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isentress 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Isentress Tablet works
Isentress 400mg Tablet is an antiviral medication. It prevents the multiplication of HIV virus in human cells. Thus stops the HIV virus from producing new viruses.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Isentress 400mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Isentress 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Isentress 400mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Isentress 400mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Isentress 400mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Isentress 400mg Tablet is recommended.
Liver
CAUTION
Isentress 400mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Isentress 400mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Isentress 400mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Limited information is available on the use of Isentress 400mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Isentress 400mg Tablet
₹140.4/Tablet
Zepdon 400mg Tablet
Cipla Ltd
₹134.18/tablet
4% cheaper
Raltegravir 400mg Tablet
Globela Pharma Pvt Ltd
₹140.4/tablet
same price
Quick tips
- Take it with or without food, preferably at the same time every day.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Do not take antacids or calcium supplements an hour before or two hours after taking Isentress 400mg Tablet.
- Your doctor may get regular blood tests done to monitor your blood cell counts and liver function during treatment with this medicine.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Fact Box
Chemical Class
Pyrrolidinone derivative
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Integrase (HIV) inhibitors
Interaction with drugs
Taking Isentress with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Fosphenytoin may affect blood levels of Raltegravir.
Do not consume Raltegravir with Fosphenytoin.
Magaldrate may reduce blood levels of Raltegravir.
Do not consume Raltegravir with Magaldrate. If concurrent use is essential, please consult your doctor.
Phenobarbitone may affect blood levels of Raltegravir.
Do not consume Raltegravir with Phenobarbitone.
Carbamazepine may affect blood levels of Raltegravir.
Do not consume Raltegravir with Carbamazepine.
Phenobarbitone may affect blood levels of Raltegravir.
Do not consume Raltegravir with Phenobarbitone.
Patient concerns
User feedback
Patients taking Isentress 400mg Tablet
Twice A Day
70%
Once A Day
30%
What are you using Isentress Tablet for?
HIV infection
100%
How much was the improvement?
Excellent
75%
Poor
17%
Average
8%
What were the side-effects while using Isentress 400mg Tablet?
Nausea
25%
Dizziness
25%
No Side Effec*
25%
Headache
25%
*No Side Effect
How do you take Isentress Tablet?
With food
100%
Please rate Isentress 400mg Tablet on price
Expensive
67%
Average
33%
FAQs
Is raltegravir a protease inhibitor?
No. Raltegravir is an anti HIV drug. It does not have any known inhibitory effect on enzyme protease
What is Isentress 400mg Tablet used for?
Isentress 400mg Tablet is used for the treatment for human immunodeficiency virus (HIV) infection
How does Isentress 400mg Tablet work?
How does Isentress 400mg Tablet inhibit HIV viral replication?Isentress 400mg Tablet works by inhibiting the action of an enzyme called integrase which is essential for the multiplication and survival of the virus (viral replication), thereby reducing HIV causing virus in the body.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Flexner C. Antiretroviral Agents and Treatment of HIV Infection. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1658-659.
- Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 866-67.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1192-194.
- Raltegravir potassium. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2007 [revised 18 Oct. 2018]. [Accessed 28 Jan 2019] (online) Available from:
- Raltegravir. Whitehouse Station, New Jersey: MERCK & CO., Inc.; 2007 [revised Jul. 2009]. [Accessed 01 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
Marketer details
Name: MSD Pharmaceuticals Pvt Ltd
Address: Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,
Country of origin: India
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