Isonex 100mg Tablet
Prescription Required
Product introduction
Isonex 100mg Tablet is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It works by killing the bacteria that cause tuberculosis.
Isonex 100mg Tablet should be used in the dose and duration as advised by your doctor. It is to be taken on an empty stomach. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.
Some common side effects of this medicine include tingling and numbness of feet and hand (peripheral neuropathy). Inform your doctor if you notice signs of jaundice, i.e., yellowing of eyes or skin, dark urine, stomach pain, or joint pain. You may also develop hepatitis (viral infection of the liver) or increased liver enzymes as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and need dose modification.
Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.
Isonex 100mg Tablet should be used in the dose and duration as advised by your doctor. It is to be taken on an empty stomach. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.
Some common side effects of this medicine include tingling and numbness of feet and hand (peripheral neuropathy). Inform your doctor if you notice signs of jaundice, i.e., yellowing of eyes or skin, dark urine, stomach pain, or joint pain. You may also develop hepatitis (viral infection of the liver) or increased liver enzymes as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and need dose modification.
Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.
Uses of Isonex Tablet
Benefits of Isonex Tablet
In Tuberculosis (TB)
Isonex 100mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills and stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.
Side effects of Isonex Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Isonex
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Hepatitis (viral infection of liver)
- Skin rash
- Lethargy
- Increased liver enzymes
How to use Isonex Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isonex 100mg Tablet is to be taken empty stomach.
Avoid Isonex 100mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Avoid Isonex 100mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
How Isonex Tablet works
Isonex 100mg Tablet is an antibiotic. It works by killing the bacteria that causes tuberculosis.
Safety advice
Alcohol
UNSAFE
Consuming alcohol while taking Isonex 100mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Isonex 100mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Isonex 100mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Isonex 100mg Tablet may cause side effects which could affect your ability to drive.
Isonex 100mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Isonex 100mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Kidney
SAFE IF PRESCRIBED
Isonex 100mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Isonex 100mg Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.
However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Isonex 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Isonex 100mg Tablet may be needed. Please consult your doctor.
Use of Isonex 100mg Tablet is not recommended in patients with severe liver disease.
Use of Isonex 100mg Tablet is not recommended in patients with severe liver disease.
What if you forget to take Isonex Tablet?
If you miss a dose of Isonex 100mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Your doctor has prescribed Isonex 100mg Tablet to cure your infection and improve symptoms.
- It is best taken on an empty stomach.
- You must also take a vitamin B6 supplement while on Isonex 100mg Tablet.
- Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.
Fact Box
Chemical Class
Nicotinic acid derivatives
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Mycolic acid inhibitors- INH
Interaction with drugs
Taking Isonex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of nerve disorders.
Do not consume Isoniazid with Stavudine.
Concurrent use may increase the risk of disturbance in heart rhythm. Isoniazid may raise blood levels of Citalopram.
If concurrent use is essential, please consult your doctor. Fac
Concurrent use may increase the risk of nerve problems.
Do not consume Didanosine with Isoniazid.
Isoniazid may fasten the elimination of Halothane leading to reduced efficacy.
Talk to your doctor if you notice any unusual symptoms.
Isoniazid may reduce blood levels of Cycloserine.
If concurrent use is essential, watch out for symptoms such as dizziness, headaches, tremors, sleep disturbances or mood changes
Patient concerns
User feedback
Patients taking Isonex 100mg Tablet
Once A Day
87%
Twice A Day
10%
Twice A Week
3%
What are you using Isonex Tablet for?
Tuberculosis *
56%
Others
44%
*Tuberculosis (TB)
How much was the improvement?
Poor
50%
Excellent
33%
Average
17%
FAQs
Is Isonex 100mg Tablet an antibiotic?
Isonex 100mg Tablet is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
Is Isonex 100mg Tablet chemotherapy/chemotherapy drug?
Isonex 100mg Tablet is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
Is Isonex 100mg Tablet bacteriostatic or bactericidal?
Isonex 100mg Tablet is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth
Is Isonex 100mg Tablet safe?
Yes. Isonex 100mg Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Is Isonex 100mg Tablet a MAOI?
Isonex 100mg Tablet has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)
Is Isonex 100mg Tablet a sulfa drug?
No. The chemical structure and mechanism of action of Isonex 100mg Tablet is different from sulfa drugs
Is Isonex 100mg Tablet an inducer or inhibitor?
Isonex 100mg Tablet is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin?
There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Does Isonex 100mg Tablet cause weight loss/weight gain/hair loss/diarrhea/affect menstruation?
Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Isonex 100mg Tablet. You may experience few of these side effects while on multi drug (including Isonex 100mg Tablet) treatment for tuberculosis
Does Isonex 100mg Tablet cause acne/make you tired/cause constipation?
You may experience unusual tiredness, constipation or acne while on treatment with Isonex 100mg Tablet. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Does Isonex 100mg Tablet affect birth control?
Isonex 100mg Tablet has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1555-558.
- Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 824-25.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 741-42.
- Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 01 Apr. 2019] (online) Available from:
- Drugs.com. Isoniazid. [Accessed 01 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:
Marketer details
Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Country of origin: India
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