Istavel 50mg Tablet
Prescription Required
Product introduction
Istavel 50mg Tablet is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels. This helps to prevent serious complications of diabetes like kidney damage and blindness.
Istavel 50mg Tablet is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or along with other diabetes medicines. It may be taken on an empty stomach or with a meal. The dose will depend on your condition, and blood sugar levels. Therefore, you should use it as advised by your doctor.
You should take it regularly at the same time each day to get the most benefit, and you should not stop unless your doctor recommends it. This medicine is helping you to control your blood sugar levels and prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.
The most common side effect of taking this medicine is a headache. This is usually minor and improves with time. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it. It may also cause upper respiratory tract infections like sore throat, cough, and cold. Contact your doctor if the side effects worry you or if they do not go away.
Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with this medicine's working. So, make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.
Istavel 50mg Tablet is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or along with other diabetes medicines. It may be taken on an empty stomach or with a meal. The dose will depend on your condition, and blood sugar levels. Therefore, you should use it as advised by your doctor.
You should take it regularly at the same time each day to get the most benefit, and you should not stop unless your doctor recommends it. This medicine is helping you to control your blood sugar levels and prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.
The most common side effect of taking this medicine is a headache. This is usually minor and improves with time. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it. It may also cause upper respiratory tract infections like sore throat, cough, and cold. Contact your doctor if the side effects worry you or if they do not go away.
Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with this medicine's working. So, make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.
Uses of Istavel Tablet
Side effects of Istavel Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Istavel
- Nasopharyngitis (inflammation of the throat and nasal passages)
- Headache
- Hypoglycemia (low blood glucose level)
How to use Istavel Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Istavel 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Istavel Tablet works
Istavel 50mg Tablet is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Istavel 50mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Istavel 50mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Istavel 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Istavel 50mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Istavel 50mg Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Istavel 50mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Istavel 50mg Tablet may not be needed in these patients. Please consult your doctor.
However, Istavel 50mg Tablet has not been studied in patients with severe hepatic impairment and is not recommended for use in such patients.
However, Istavel 50mg Tablet has not been studied in patients with severe hepatic impairment and is not recommended for use in such patients.
What if you forget to take Istavel Tablet?
If you miss a dose of Istavel 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Istavel 50mg Tablet should be taken at the same time every day since this helps you remember to take it.
- It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
- Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
- Be careful while driving or operating machinery until you know how Istavel 50mg Tablet affects you.
- Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.
- Istavel 50mg Tablet should be taken at the same time every day since this helps you remember to take it.
- Be careful while driving or operating machinery until you know how Istavel 50mg Tablet affects you.
- You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with this medicine.
- It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
- Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
- Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
- Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.
- Monitor your blood sugar level regularly while taking this medicine.
Fact Box
Chemical Class
Pyrazine-derivative
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Action Class
Dipeptidyl Peptidase-4 (DPP-4) Inhibitors
Interaction with drugs
Taking Istavel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of low blood sugar levels. Elderly, malnourished, diabetic individuals and those with kidney and heart dysfunction are at higher risk.
If conc
If used together, Bortezomib may interrupt with efficacy of Sitagliptin.
Your doctor may monitor your blood glucose levels along with your overall treatment closely and adjust the
Concurrent use may increase the risk of high blood sugar levels.
If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per
Concurrent use may interfere with control over blood sugar.
Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.
Concurrent use may interfere with control over blood sugar.
Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.
Patient concerns
FAQs
Does Istavel 50mg Tablet cause weight gain?
No, Istavel 50mg Tablet is not known to cause weight gain by itself. However, keeping a healthy weight is an important part of managing diabetes. Consult your doctor if you experience weight gain while taking Istavel 50mg Tablet.
Is Istavel 50mg Tablet bad for your kidneys?
No, Istavel 50mg Tablet is not bad for your kidneys if your kidney function is normal. However, it is important to inform your doctor if you have, or ever had, any kidney problems. If you have kidney problems, you may need dose modification.
Do I still have to manage my diet and exercise while on Istavel 50mg Tablet?
Yes, it is important to manage your diet and exercise while taking Istavel 50mg Tablet. In addition to medicine, making healthy food choices and being physically active are also important to effectively manage blood sugar levels. You may consult a dietitian and follow a diet chart that suits you best. A well-balanced diet is one part of a healthy lifestyle for people with type 2 diabetes. Additionally, thirty minutes of exercise such as a brisk walk is recommended.
Can my blood sugar levels go too low on Istavel 50mg Tablet?
Yes, it is possible that your blood sugar levels may become very low (hypoglycemia). The chances are higher if you are on any other antidiabetic medicine or insulin along with Istavel 50mg Tablet. Additionally, blood sugar levels can take a huge dip if you skip meals, exercise more than usual, or if you have taken an overdose of Istavel 50mg Tablet. If you experience a sudden fall in your sugar levels, inform your doctor. The doctor may suggest dose modification to prevent your blood sugar levels from decreasing significantly (hypoglycemia). Follow your doctor’s advice and monitor your blood sugar levels regularly.
What will happen if I accidentally take more than the prescribed dose of Istavel 50mg Tablet?
If you have accidentally taken more than the prescribed dose of Istavel 50mg Tablet, your blood sugar levels may become too low (hypoglycemia). This hypoglycemia may be mild or severe. Monitor your blood sugar levels more frequently for the next 24 hours. Mild episodes of hypoglycemia (with symptoms like anxiety, sweating, weakness, tremors, fast heartbeat) can usually be corrected with the help of sugary foods such as sugar or glucose candy, fruit juice and glucose/glucon-D. However, it is important to consult your doctor to decide the further course of treatment. More severe episodes of hypoglycemia may even lead to a seizure (fit) or unconsciousness. This can be life-threatening and immediate medical help may be required.
What if I miss a dose of Istavel 50mg Tablet?
If you miss a dose, take it as soon as you remember. If in case you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of Istavel 50mg Tablet at the same time.
Is Istavel 50mg Tablet safe to be taken for a long term?
Yes, it is safe to take Istavel 50mg Tablet for a long time. Its long-term use, which can continue for months, years or even lifelong, has not shown any harmful effects. Keep taking Istavel 50mg Tablet as long as your doctor recommends it. Remember, Istavel 50mg Tablet only helps to keep your blood sugar levels under control but does not cure your diabetes.
How long do I need to take Istavel 50mg Tablet?
Istavel 50mg Tablet only helps to manage your blood sugar levels but does not cure your diabetes. Keep taking Istavel 50mg Tablet as long as your doctor recommends it. You may have to take it lifelong. It is important to keep your blood sugar levels under control as any fluctuations in your blood sugar levels may cause serious problems. Therefore, do not stop taking it without talking to your doctor.
What is the most important information I should know about Istavel 50mg Tablet?
Istavel 50mg Tablet is safe to use if taken in the dose and duration prescribed by the doctor. However, in rare cases, some serious side effects can also be observed. In some people, Istavel 50mg Tablet may cause inflammation of the pancreas (pancreatitis) which could be severe and can even lead to death. If you experience severe and persistent pain in your stomach area (abdomen), stop the medication and immediately contact your doctor. Istavel 50mg Tablet can also cause heart failure. This means the heart is not able to pump blood well enough, therefore, inform your doctor if you have or ever had heart problems before you start taking Istavel 50mg Tablet. In addition to that, problems related to kidneys should also be discussed with the doctor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1264-65.
- Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 45.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1268-69.
- Sitagliptin. Pavia, Italy: Merck Sharp & Dohme (Italia) S.p.A.; 2006 [revised 2010]. [Accessed 12 Mar. 2019] (online) Available from:
- Sitagliptin [Product Monograph]. Kirkland, Canada: Merck Canada Inc.; 2021. [Accessed 8 Oct. 2021] (online) Available from:
- Sitagliptin [FDA Label]. Northumberland, UK. Merck Sharp & Dohme Ltd.; 2012. [Accessed 8 Oct. 2021] (online) Available from:
- Sitagliptin [Product Information]. [Accessed 8 Oct. 2021] (online) Available from:
- Sitagliptin [Package Insert]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2022. [Accessed 06 Aug. 2023]. (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
Expires on or after: April, 2025
A licensed vendor partner from your nearest location will deliver Istavel 50mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: April, 2025
A licensed vendor partner from your nearest location will deliver Istavel 50mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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