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Isuvaz 100 Capsule

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Isuvaz 100 Capsule is an antifungal medicine. It is used to treat certain types of fungal infections called invasive aspergillosis and invasive mucormycosis in patients 18 years of age and older. It works by stopping the growth of fungi in the body.

Isuvaz 100 Capsule can be taken with or without food. Take it exactly as your doctor has advised. Swallow the whole capsule, do not chew, crush, dissolve, or open the capsules. Continue to take the medicine until you finish your complete course, even if symptoms disappear after a few days. Stopping it too early may result in a return of the infection.

The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, increased liver enzymes, decreased potassium level in blood, constipation, breathlessness, cough, peripheral edema, and back pain. If any of these side effects persist or worsen, consult with your doctor. In rare cases, Isuvaz 100 Capsule may cause serious liver disease. Get medical help right away if you have any symptoms of liver damage, including persistent nausea/vomiting, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, or dark urine.

Before taking the medicine, tell your doctor if you have any known history of allergy to this medicine. Let your doctor also if you have any preexisting medical conditions, especially liver disease and heart problems. This medicine may make you dizzy. Avoid consumption of alcohol while on treatment with this medicine. Additionally, do not drive, use machinery, or do anything that needs alertness until you know how the medicine works. Before taking this medicine, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as it can cause harmful effects to the developing baby.

There is a Patient Support Program / Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Isuvaz Capsule

  • Treatment of Invasive Aspergillosis

Benefits of Isuvaz Capsule

In Treatment of Invasive Aspergillosis

Invasive Aspergillosis occurs when the infection spreads rapidly from the lungs to the brain, heart, kidneys or skin, in patients with compromised immunity, such as those under cancer therapy, bone marrow transplantation or any other immune related disorder. Isuvaz 100 Capsule helps treat invasive Aspergillosis and helps you recover faster. Follow your doctor’s instructions carefully while on treatment with Isuvaz 100 Capsule.

Side effects of Isuvaz Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Isuvaz

  • Abnormal liver function tests
  • Headache
  • Decreased potassium level in blood
  • Breathlessness
  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea

How to use Isuvaz Capsule

Take this medicine in the dose and duration as advised by your doctor. Isuvaz 100 Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Isuvaz Capsule works

Isuvaz 100 Capsule contains Isavuconazole, an antifungal medicine that blocks the activity of an enzyme that aids in the synthesis of ergosterol, a key component of the fungal cell membrane. As a result, the fungus fails to grow and multiply. This kills the infection causing fungus and clears the infection.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Isuvaz 100 Capsule.
Pregnancy
CONSULT YOUR DOCTOR
Isuvaz 100 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Isuvaz 100 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Isuvaz 100 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Isuvaz 100 Capsule is safe to use in patients with kidney disease. No dose adjustment of Isuvaz 100 Capsule is recommended.
Liver
SAFE IF PRESCRIBED
Isuvaz 100 Capsule is safe to use in patients with liver disease. No dose adjustment of Isuvaz 100 Capsule is recommended.
However, clinical monitoring for isavuconazole-related adverse reactions is recommended when treating patients with severe hepatic impairment.

What if you forget to take Isuvaz Capsule?

If you miss a dose of Isuvaz 100 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Isuvaz 100 Capsule
₹1097.0/Capsule
₹2465.07/capsule
125% costlier

Quick tips

  • Isuvaz 100 Capsule is used for the treatment of certain fungal infections in adults.
  • Inform your doctor if you have or ever had an abnormal heart rate or rhythm. He/she may ask you to get a test to check your heart (ECG) before starting the treatment.
  • Inform your doctor if you experience serious hypersensitivity and severe skin reactions after taking Isuvaz 100 Capsule.
  • Isuvaz 100 Capsule might interact with certain antibiotics and pain killers. Inform your doctor if you are taking any.
  • Let your doctor know if you are pregnant or breastfeeding.
  • Isuvaz 100 Capsule is used for the treatment of certain fungal infections in adults.
  • Inform your doctor if you have or ever had an abnormal heart rate or rhythm. He/she may ask you to get a test to check your heart (ECG) before starting the treatment.
  • Inform your doctor if you experience serious hypersensitivity and severe skin reactions after taking Isuvaz 100 Capsule.
  • Isuvaz 100 Capsule might interact with certain antibiotics and pain killers. Inform your doctor if you are taking any.
  • Let your doctor know if you are pregnant or breastfeeding.

Fact Box

Chemical Class
Phenyl propane derivatives
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Fungal ergosterol synthesis inhibitor

Interaction with drugs

Taking Isuvaz with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Isavuconazole may raise blood levels of Docetaxel. If concurrent use is essential, watch out for symptoms such as bruising, pink urine, nosebleeds, diarrhea, stomach cramps, or bl... More
Sirolimus may increase the metabolism of Isavuconazole. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Concurrent use may increase the risk of fatal disturbances in heart rhythm. Isavuconazole may raise blood levels of Ranolazine. watch out for symptoms of Isavuconazole side effects... More
Concomitant use may affect heart rhythm and can be fatal. Do not consume Pimozide with Isavuconazole.
Sirolimus may increase the metabolism of Isavuconazole. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Patient concerns

Sir I want to ask that which itraconazole capsule is effective more. Canditral 100mg or candiforce 100 mg.i am taking canditral 100 mg but it is too much costlier than candiforcw.please suggest me. I am a allergic bronchi pulmonary aspergillosis patient Please suggest me could I take candiforce100mg.is it will be effective as like canditral 100mg
Dr. Sfurti Mann
Internal Medicine
Itraconazole may be given for aspergillosis but generally not too useful If no symptoms usually it can be left as it isI can not comment on the brand of medicine

FAQs

What is Isuvaz 100 Capsule? What is it used for?

Isuvaz 100 Capsule is a broad spectrum activity antifungal medicine, which is safe and effective to use. It is used to treat invasive aspergillosis and mucormycosis.

What should I tell my doctor before starting treatment with Isuvaz 100 Capsule?

Before starting treatment with Isuvaz 100 Capsule, tell your doctor if you have any other health problems, like heart or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are planning a baby, if you are pregnant or breastfeeding.

Who should not take Isuvaz 100 Capsule?

Isuvaz 100 Capsule should be taken by anyone who is allergic to Isuvaz 100 Capsule, or any of its ingredients. Let your doctor know about any medicines that you may be taking like, ketoconazole, carbamazepine, rifampin, long-acting barbiturates, high-dose ritonavir or any herbal supplements, as their use is contraindicated along with Isuvaz 100 Capsule. Also, if you have any issues with your heart, discuss with your doctor, as there are certain problems of the heart in which the use of Isuvaz 100 Capsule is contraindicated. It is advised to avoid starting any new medicines while on treatment with Isuvaz 100 Capsule to avoid any unwanted sid effects. If you are not sure, please consult your doctor.

Can I stop taking Isuvaz 100 Capsule when I feel better?

No, do not stop taking Isuvaz 100 Capsule without consulting your doctor even if you are feeling better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.

What if I forget to take a dose of Isuvaz 100 Capsule?

If you forget a dose of Isuvaz 100 Capsule, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Is Isuvaz 100 Capsule safe?

Isuvaz 100 Capsule is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Isavuconazonium sulfate [EMC Label]. Sandwich, Kent: Pfizer Limited; 2021. [Accessed 03 Jul. 2021] (online) Available from: External Link
  2. Isavuconazonium sulfate [Prescription Information]. Northbrook, IL: Astellas Pharma US, Inc.; 2021. [Accessed 03 Jul. 2021] (online) Available from:External Link
  3. CRESEMBA® (isavuconazonium sulfate). [Accessed 03 Jul. 2021] (online) Available from:External Link
  4. Isavuconazonium sulfate [Dosing and Administration Guide]. Astellas Pharma US, Inc.; 2022. [Accessed 05 Jul. 2023]. (online) Available from:External Link
  5. Isavuconazole [Drug Label]. Craigavon, United Kingdom: Almac Pharma Services Limited; 2022. [Accessed 05 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Glenmark Pharmaceuticals Ltd
Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Country of origin: India
Expires on or after: March, 2025

A licensed vendor partner from your nearest location will deliver Isuvaz 100 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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