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MD Pharmacology, MBBS
Last updated
08 Nov 2024 | 11:12 AM (IST)

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Kallistat Injection

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Kallistat Injection is used to treat bleeding. It helps to prevent or reduce heavy bleeding after any surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, or nosebleeds.

Kallistat Injection must be administered under the supervision of a healthcare professional. Do not self-administer this medicine at home. You should not use it if you have any known allergies from this injection.

It may cause injection site reactions such as pain, swelling, and redness in some people. Let your doctor know if they bother you. Additionally, inform your doctor if you have undergone any cardiac surgery or you are suffering from any liver disease.

Uses of Kallistat Injection


Side effects of Kallistat Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Kallistat

  • Injection site reactions (pain, swelling, redness)

How to use Kallistat Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Kallistat Injection works

Kallistat Injection prevents the breakdown of clots and stops bleeding.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Kallistat Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Kallistat Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Kallistat Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
NOT RELEVANT
Not relevant, as Kallistat Injection is intended for use in hospitalised patients.
Kidney
SAFE IF PRESCRIBED
Kallistat Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Kallistat Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Kallistat Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Kallistat Injection?

If you miss a dose of Kallistat Injection, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Kallistat Injection helps prevent or reduce heavy bleeding post surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, and nosebleeds.
  • It is given as a slow injection into a vein.
  • Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
  • Your doctor may monitor your vision regularly while you are taking this medicine.
  • Inform your doctor if you have a history of kidney or liver disease.
  • Kallistat Injection helps prevent or reduce heavy bleeding post surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, and nosebleeds.
  • Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
  • If taking for heavy periods, take it on the first day as taking it before or after will not have any benefit.
  • Your doctor may monitor your vision regularly while you are taking this medicine.
  • Inform your doctor if you have a history of kidney or liver disease.
  • Inform your doctor if there is no improvement in your bleeding after using this medicine for three consecutive periods.

Fact Box

Chemical Class
Amino Acids, Peptides Analogues
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Antifibrinolytic Agents

Interaction with drugs

Taking Kallistat with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Tretinoin may increase the side effects of Aprotinin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Concurrent use may increase the risk of kidney dysfunction. Your doctor may monitor your kidney function regularly during the simultaneous use of these medicines and adjust doses ... More
Concurrent use may increase the risk of kidney dysfunction. Your doctor may monitor your kidney function regularly during the simultaneous use of these medicines and adjust doses ... More
Concurrent use may increase the risk of kidney dysfunction. Your doctor may monitor your kidney function regularly during the simultaneous use of these medicines and adjust doses ... More
Concurrent use may increase the risk of kidney dysfunction. Your doctor may monitor your kidney function regularly during the simultaneous use of these medicines and adjust doses ... More

Patient concerns

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I was late on my dates this month and now having heavy bleeding with thick fluid (clots) passage from past 6-7 days This is for the 1st time happening and I am really worried.Please suggest and advice the medication
Dr. Megha Tuli
Obstetrics and Gynaecology
Heavy bleeding is expected after a delayed period. Try Tranexa tablets to control the bleeding.
Suddenly from last two months m having bleeding only for 1 day during periods .I want to know reason behind it.i am taking Diane 35 now.but still the bleeding lasts for 1 day.The flow of bleeding is very slow.kindly give your suggestions.
Dr. Megha Tuli
Obstetrics and Gynaecology
Hi dear. Usually bleeding decreases while on Diane 35. Also amount if bleeding would depend on how you are taking the pills. However don't worry, decrease in bleeding is expected.
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FAQs

What Kallistat Injection is and what it is used for?

Kallistat Injection belongs to a group of medicines called antifibrinolytics, i.e. medicines to prevent blood loss.

How is Kallistat Injection given?

This injection will usually be given to you lying down by slow injection or infusion (through ‘a drip’) through a catheter into a larger vein in your body.

Can Kallistat Injection be given to children?

This injection should be avoided in children since its safety and efficacy in children below the age of 18 years have not been established. Consult your doctor for more advice.

What other medications should be avoided while taking Kallistat Injection?

It is advisable to avoid taking any other anti-fibrinolytic and antibiotics while taking Kallistat Injection. Inform your doctor before the start of the treatment if you are taking any of these.

What are some of the serious side-effects of Kallistat Injection?

Some of the serious side-effects of this medicine are blood clots in the lungs, severe blood clotting disorder that results in tissue damage and bleeding, the inability of the blood to clot or coagulate normally, chest pain, and severe allergic shock (anaphylactic shock), which is potentially life-threatening. In such cases, your doctor will stop the treatment completely.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Aprotinin. West Haven, CT: Bayer Pharmaceuticals Corporation; 2003. [Accessed 07 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Aprotinin. [Accessed 04 Feb. 2019] (online) Available from:External Link
  3. Aprotinin. West Haven, CT: Bayer Pharmaceuticals Corporation; 2006. [Accessed 07 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Biosena Lifescience
Address: Biosena Life Sciences, 14, 1st Floor, 1st Main, 1st Cross, Basveshwara Layout, Naga shettyhalli, Bengaluru-560094, Karnataka, India
Country of origin: India

1309
Inclusive of all taxes
MRP1350  3% OFF
50.0 ml in 1 vial
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