Kkzole Tablet belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat infections of the mouth, throat, vagina, and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane.
Kkzole Tablet should be taken in the dose and duration as prescribed by your doctor. They should be swallowed whole and taken with food. The dosage and length of treatment will depend on the condition you are being treated for. Sometimes this will be in cycles of use and non-use. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse. Avoid taking antacid treatments within one hour before or two hours after you take it.
The most common side effects of this medicine include stomach pain, headache, feeling sick (nausea), and abnormal liver function. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction. Signs of this include rash, swelling of the lips, throat or face, swallowing or breathing problems, feeling dizzy or faint, and nausea. Get emergency help if this happens.
Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, a weak immune system (including HIV/AIDS), or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver by testing your blood. The drugs may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Kkzole
Nausea
Vomiting
Abdominal pain
Itching
Diarrhea
Abnormal liver function tests
How to use Kkzole Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kkzole Tablet is to be taken with food.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Kkzole Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Kkzole Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Kkzole Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Kkzole Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Kkzole Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Kkzole Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Kkzole Tablet should be used with caution in patients with liver disease. Dose adjustment of Kkzole Tablet may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Your doctor has prescribed Kkzole Tablet to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Take it with food, preferably at the same time every day.
Do not take indigestion remedies (antacids) within two hours of taking Kkzole Tablet.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Inform your doctor if you experience an allergic reaction like skin rash, swelling of face and shortness of breath.
Fact Box
Chemical Class
Azole derivatives {Imidazoles}
Habit Forming
No
Therapeutic Class
OPHTHAL OTOLOGICALS
Action Class
Fungal Ergosterol Synthesis Inhibitor
Interaction with drugs
Taking Kkzole with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Simvastatin with Ketoconazole. If Ketoconazole is essential, your doctor may temporarily stop Simvastatin. Ketoconazole may raise blood levels of Simvastatin.
Concur... More
Do not consume Lovastatin with Ketoconazole. If Ketoconazole is essential, your doctor may temporarily stop Lovastatin. Ketoconazole may raise blood levels of Lovastatin.
Concurren... More
Do not consume Ranolazine with Ketoconazole. If concurrent use is essential, watch out for symptoms such as tiredness, nausea, palpitations or numbness. Your doctor may monitor you... More
Do not consume Methylergometrine with Ketoconazole. Ketoconazole may raise blood levels of Methylergometrine.
Concurrent use may cause gangrene of fingers and toes.
Do not consume Methylergometrine with Ketoconazole. Ketoconazole may raise blood levels of Methylergometrine.
Concurrent use may cause gangrene of fingers and toes.
I am regularly using the cream cosmelite But now due to a fungal infection i have to use a antifungal cream fungicros So So i want to know whether i can apply the cream cosmelite after fungicros
Dr. Atul Jain
Dermatology
Pls tell me which part of body have fungal infections
Stop all other applications. Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks. Sertacide Cream for application twice daily for 1 month.Tab. Fexova 180 mg (if required in case of itching) Test ? Blood sugar ( Fasting & PP) The treatment has to be complete otherwise it will be recur.
Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks.Sertacide Cream for application twice daily for 1 month.Send pictures for better diagnosis and treatment
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References
Schimmer BP, Funder JW. ACTH, Adrenal Steroids, and Pharmacology of the Adrenal Cortex. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1233.
Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1576.
Chrousos GP. Adrenocorticosteroids & Adrenocortical Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 693.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 758-59.
Ketoconazole. Titusville, New Jersey: Janssen Pharmaceuticals, Inc.; 2014. [Accessed 29 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:
Ketoconazole [Prescribing Information]. Titusville, New Jersey: Janssen Pharmaceuticals, Inc.; 2014. [Accessed 13 Mar. 2024] (online) Available from: