Koxylar 400mg Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.

Koxylar 400mg Tablet is usually given in combination with at least one other tuberculosis medicine. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose as it may increase the side effects.

Some people may experience visual impairment and color blindness, as side effects of this medicine. Please consult your doctor if these side effects do not resolve or worsen. Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine.

Uses of Koxylar Tablet

Tuberculosis (TB)

Benefits of Koxylar Tablet

In Tuberculosis (TB)

Koxylar 400mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Koxylar Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Koxylar

Visual impairment
Color blindness

How to use Koxylar Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Koxylar 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Koxylar Tablet works

Koxylar 400mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Koxylar 400mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Koxylar 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Koxylar 400mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Koxylar 400mg Tablet may cause side effects which could affect your ability to drive.
Koxylar 400mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.

Kidney

CAUTION

Koxylar 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Koxylar 400mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.

Liver

CAUTION

Koxylar 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Koxylar 400mg Tablet may be needed. Please consult your doctor.

What if you forget to take Koxylar Tablet?

If you miss a dose of Koxylar 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Koxylar 400mg Tablet

₹1.51/Tablet

Combutol 400 Tablet

Lupin Ltd

₹2.71/tablet

79% costlier

Mycobutol 400 Tablet

Cadila Pharmaceuticals Ltd

₹2.72/tablet

80% costlier

Themibutol 400mg Tablet

Themis Medicare Ltd

₹2.27/tablet

50% costlier

Ebutol 400mg Tablet

Novartis India Ltd

₹2.03/tablet

34% costlier

ALBUTOL 400MG TABLET

Alkem Laboratories Ltd

₹0.71/tablet

53% cheaper

View all substitutes

Quick tips

Koxylar 400mg Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
It has to be taken for several months in order for it work properly (usually 6 months).
Take it with food to avoid stomach upset.
It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
Avoid consuming alcohol while taking this medication.
Do not stop taking Koxylar 400mg Tablet even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Fact Box

Chemical Class

1,2-Aminoalcohols

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Mycobacterial cell wall inhibitors-Ethambutol

Interaction with drugs

Taking Koxylar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Isoniazid (Oral Route) Moderate

Ethambutol may raise blood levels of the active form of Isoniazid. Talk to your doctor if you notice any unusual symptoms.

View all drug interactions

Patient concerns

My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???

Dr. Rahul Yadav

Paediatrics

Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.

Extra pulmonary tuberculosis mdr tb for spinal card treatment

Dr. Sunil Sekhri

Diabetology

This needs to be examined and treated in the clinic

Doctor asked me to do TB GOLD test. But there is no lab test on 1mg with so name. Finally I searched for tuberculosis test and I found two test. 1 is Mycobacterium tuberculosis and other 1 is Mycobacterium tuberculosis sputum. Kindly tell me which test is to be selected and proceeded further.

Dr. Gopal Bansilal Samdani

Paediatrics

Please follow your doctors advise as he has clinical examination data with him. He can advise you for place where you can do TB gold

FAQs

My child vomited after taking Koxylar 400mg Tablet. What should be done?

If your child vomited within 30 minutes of taking Koxylar 400mg Tablet, give the same dose again. If vomiting occurred 30 minutes after taking Koxylar 400mg Tablet, you need not repeat the dose. If your child vomits again after taking Koxylar 400mg Tablet, consult your doctor.

For how long does Koxylar 400mg Tablet stay in your system?

Koxylar 400mg Tablet stays for about 24 hours in your system. This duration varies from person to person and maybe different for patients with kidney problems.

Will Koxylar 400mg Tablet work if I have developed tuberculosis for the second time?

Yes, it will work if you had taken proper treatment and got cured when you developed tuberculosis for the first time. If you have any doubt, ask your doctor.

Is it necessary to take so many TB drugs simultaneously? Is there no single medicine which can provide a cure for tuberculosis?

Yes, it is important that you take all the prescribed TB drugs together for the recommended duration, else you will not be cured. A single drug is not prescribed to treat TB because it may increase the risk of developing multi-drug resistant tuberculosis, which is very difficult to treat.

What is drug resistance? Can I become resistant to Koxylar 400mg Tablet?

Sometimes it happens that bacteria gets modified in your body and stops reacting to the medicine. As a result, the medicine stops working. This is called drug resistance. Drug resistance is uncommon if Koxylar 400mg Tablet is used in combination with other TB drugs.

Can Koxylar 400mg Tablet treatment be taken for more than two months?

Yes, Koxylar 400mg Tablet can be continued for more than 2 months, depending on your condition and as per your doctor’s advice. If after 2 months, your investigations show that the TB bacteria are still active, you may have to take Koxylar 400mg Tablet for 1 more month. In case you are resistant to other TB drugs, you may have to take Koxylar 400mg Tablet and other TB drugs (for which you are not drug resistant) for longer than 2 months.

What are the warning signals which should prompt me to stop taking Koxylar 400mg Tablet?

You should consult your doctor and consider stopping the medicine immediately if you develop any vision problems like blurred vision, color blindness or any kidney problems like decreased amount of urine and swelling of your legs and feet. You may even develop liver troubles like nausea, vomiting and yellowish color of skin and eyes. Beware of all these symptoms and consult your doctor immediately.

Show less

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

Top Physicians

4.5 ★

4.3 ★

4.3 ★

4.1 ★

4.1 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1558-559.
Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 826-27.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 506.
Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 01 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:

Marketer details

Name: Lark Laboratories Ltd

Address: A-105/2, Okhla Industrial Area, Phase-II, New Delhi-110020

Country of origin: India

NOT FOR SALE

We do not facilitate sale of this product at present

We provide you with authentic, trustworthy and relevant information

Have issue with the content?