Leafine 250mg Tablet belongs to a group of medicines called antifungals It is used to treat a wide range of fungal infections of the skin and nails, including ringworm. It works by killing the fungi that cause the infection.

Leafine 250mg Tablet can be taken with or without food. You should take it regularly as prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. If you stop taking this medicine too early, the fungus may continue to grow and the infection may return or worsen.

This medicine's most common side effects include rash, headache, nausea, and abnormal liver enzyme. These are usually mild but let your doctor know if they bother you or last more than a few days.

Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. Your doctor will monitor your liver function regularly during treatment.

Uses of Leafine Tablet

Fungal infections

Benefits of Leafine Tablet

In Fungal infections

Leafine 250mg Tablet is an antifungal medicine. It works by killing and stopping the growth of fungus causing the infection. The dose and duration of treatment will depend on what you are being treated for. Make sure you complete the full dose your doctor has prescribed. This will ensure that the infection is completely cured and prevent it from returning.

Side effects of Leafine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Leafine

Headache
Taste change
Nausea
Abdominal pain
Diarrhea
Rash
Indigestion
Abnormal liver enzyme
Flatulence
Itching

How to use Leafine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leafine 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Avoid Leafine 250mg Tablet with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.

How Leafine Tablet works

Leafine 250mg Tablet is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Leafine 250mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Leafine 250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Leafine 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Leafine 250mg Tablet may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Leafine 250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Leafine 250mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Leafine 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Leafine 250mg Tablet may be needed. Please consult your doctor.

What if you forget to take Leafine Tablet?

If you miss a dose of Leafine 250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Leafine 250mg Tablet

₹16.3/Tablet

Terbinaforce Tablet

Mankind Pharma Ltd

₹16.29/tablet

same price

Gris ODT Tablet

Eris Oaknet Healthcare Pvt Ltd

₹33.71/tablet

107% costlier

Terbitotal Tablet

Macleods Pharmaceuticals Pvt Ltd

₹14.29/tablet

12% cheaper

Tebina Tablet

Intas Pharmaceuticals Ltd

₹20.71/tablet

27% costlier

Terbocet 250 Tablet

Kivi Labs Ltd

₹17.8/tablet

9% costlier

View all substitutes

Quick tips

Leafine 250mg Tablet helps treat fungal infections of the skin and nails.
Do not skip any doses and finish the full course of treatment even if you feel better.
Treatment may be needed for 2 to 6 weeks for skin infections and 6 weeks to 6 months for nail infections.
Your doctor may monitor your liver function regularly during treatment. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.

Fact Box

Chemical Class

Allylamine

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Fungal ergosterol synthesis inhibitor

Patient concerns

Medicine for fungal infections.

Dr. Atul Jain

Dermatology

There is hundred type of fungal infectionFrom which you sufferBetter visit clinic for proper examination

Fungal infections on body & face

Dr. Atula Gupta

Dermatology

Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks.Sertacide Cream for application twice daily for 1 month.Send pictures for better diagnosis and treatment

FAQs

Can Leafine 250mg Tablet be safe for use in patients with liver cirrhosis?

Oral intake of Leafine 250mg Tablet is not recommended in patients with chronic or active liver disease. Your doctor may prescribe a liver function test to check whether the liver is functioning effectively or not. This is done because the medicine gets metabolized by liver enzymes and any inefficiency in liver function can lead to increased levels of the medication in the blood, resulting in increased side effects and toxicity. Therefore, it is important to inform your doctor if you have any liver disease or cirrhosis. Also, inform your doctor about the medicines you may be taking as taking Leafine 250mg Tablet with another medicine can lead to liver toxicity and Leafine 250mg Tablet by acting on the liver enzymes can change the levels of other drugs. Your doctor may suggest periodic monitoring (after 4-6 weeks of treatment) of liver function test and make dose adjustments accordingly.

Does Leafine 250mg Tablet cause any skin reactions?

Yes, sensitive individuals may develop skin reactions while using Leafine 250mg Tablet. There are rare reports of people developing serious skin/hypersensitivity reactions like Stevens-Johnson syndrome, toxic epidermal necrolysis, and other severe skin reactions with Leafine 250mg Tablet. Therefore, do not take this medication without consulting your physician. And, in case you encounter any type of skin reaction or rashes, stop the medication immediately and report to the doctor.

Is Leafine 250mg Tablet effective?

Leafine 250mg Tablet is effective as an anti fungal medicine if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop taking this medicine too early, the fungus may continue to grow and the infection may return or worsen.

How long do I need to take Leafine 250mg Tablet?

The usual duration of treatment for Tinea pedis (fungal infection in the foot), Tinea corporis (ringworms), and Tinea cruris (fungal infection in the groin) is about 2 to 4 weeks. The duration may sometimes be extended to 6 weeks. For fungal infections of nails, the duration of treatment usually varies from 6 to 12 weeks. For fingernail fungal infections it may take 6 weeks whereas toenail fungal infection may take about 12 weeks. However, the exact duration of the therapy is decided by the doctor depending upon the type of infection, the site of infection, and the patient’s response to the therapy.

Can I drink tea or coffee while taking Leafine 250mg Tablet?

Caffeinated drinks like tea and coffee should be taken with caution while being on treatment with Leafine 250mg Tablet. Leafine 250mg Tablet decreases the rate of metabolism of caffeine by 19% which is an important constituent of coffee, thereby increasing the levels of caffeine in the blood. These increased levels of caffeine may lead to side effects such as jitteriness, headache, increased heartbeat, and restlessness.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1586, 1588.
Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1051, 1053.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1329.
Mayo Clinic. Terbinafine. [Accessed 29 Mar. 2019] (online) Available from:
Terbinafine hydrochloride [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2012. [Accessed 28 Mar. 2023] (online) Available from:

Marketer details

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Address: Plot No. 11-12, Danik Bhaskar Building Sector 25-D, Chandigarh - 160014, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.