Lenava 10 Capsule
Prescription Required
Product introduction
Lenava 10 Capsule belongs to a group of medicines that affect how your immune system works. $It is used in the treatment of multiple myeloma and myelodysplastic syndrome.
Lenava 10 Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include headache, weakness, nausea, rash, and dizziness amongst others. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Hence, take caution while performing the activity that might increase your chances of bleeding or avoid contact with people suffering from an infection such as a cold. Regular blood tests are required to check your blood cells while on treatment.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You are advised to drink plenty of fluids to stay hydrated while taking this medicine.
Uses of Lenava Capsule
Benefits of Lenava Capsule
In Treatment of Multiple myeloma
If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Lenava 10 Capsule may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.
In Treatment of Myelodysplastic syndrome
Myelodysplastic Syndromes (MDS) are a group of rare blood disorders characterized by abnormal development of blood cells in the bone marrow. In MDS, the bone marrow fails to produce enough healthy and fully matured blood cells, leading to low blood cell counts, which can result in anemia, infections, and bleeding problems.
Lenava 10 Capsule is used to treat certain types of MDS, specifically those associated with a specific part of the chromosomes in the blood cells. It works by helping the immune system make more healthy blood cells in the bone marrow. Lenava 10 Capsule helps improve the production of red blood cells, reducing the need for frequent blood transfusions and making them feel better. It is important to check-up and monitor regularly to make sure it is safe and effective.
Lenava 10 Capsule is used to treat certain types of MDS, specifically those associated with a specific part of the chromosomes in the blood cells. It works by helping the immune system make more healthy blood cells in the bone marrow. Lenava 10 Capsule helps improve the production of red blood cells, reducing the need for frequent blood transfusions and making them feel better. It is important to check-up and monitor regularly to make sure it is safe and effective.
Side effects of Lenava Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lenava
- Headache
- Nausea
- Rash
- Breathlessness
- Dizziness
- Fatigue
- Decreased white blood cell count (neutrophils)
- Joint pain
- Itching
- Diarrhea
- Low blood platelets
- Peripheral edema
- Cough
- Back pain
- Upper respiratory tract infection
- Decreased appetite
- Nasopharyngitis (inflammation of the throat and nasal passages)
How to use Lenava Capsule
Take this medicine in the dose and duration as advised by your doctor. Lenava 10 Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Lenava Capsule works
Lenava 10 Capsule is an anti-cancer medication. It works by enhancing the immune system that indirectly attacks the cancer cells. It prevents the growth of new blood vessels within the tumor. It also restricts the production of chemical messengers (cytokine and growth factor) which are responsible for the growth of cancer cells. This is how it works against cancer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lenava 10 Capsule. Please consult your doctor.
Pregnancy
UNSAFE
Lenava 10 Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Lenava 10 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Lenava 10 Capsule may cause side effects which could affect your ability to drive.
You may feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Lenava 10 Capsule and this may affect your ability to drive.
You may feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Lenava 10 Capsule and this may affect your ability to drive.
Kidney
CAUTION
Lenava 10 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Lenava 10 Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Lenava 10 Capsule should be used with caution in patients with liver disease. Dose adjustment of Lenava 10 Capsule may be needed. Please consult your doctor.
What if you forget to take Lenava Capsule?
If you miss a dose of Lenava 10 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- You may be monitored with regular blood tests before and during the treatment as lenalidomide may cause a fall in the white blood cells and platelets, required to fight infection, Hemoglobin and blood clotting.
- Avoid activities that may cause bruising or injury and avoid contact with people who have colds or infections.
- It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective while going out.
- It may cause dehydration. Drink plenty of water to stay hydrated while taking medication.
- It is not recommended for use in children and adolescents under 18 years.
- You should use proper contraceptive methods at least 4 weeks before, during and until 4 weeks after stopping treatment.
- Woman of childbearing potential will be required to undergo pregnancy tests before and after the treatment.
- You should inform your doctor or dentist that you are taking Lenava 10 Capsule before you receive any medical or dental care, emergency care, or surgery.
- It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- You may be at risk of developing acute myelogenous leukemia, fatal liver problems, severe skin reactions, and fatal heart problems during treatment with Lenava 10 Capsule. You should discuss in advance the benefits and risks of taking this medicine.
Fact Box
Chemical Class
Phthalimide and Piperidone Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Thalidomide & its Immunomodulatory derivatives (IMiDs)
Patient concerns
FAQs
Q. Can I take Lenava 10 Capsule empty stomach?
Lenava 10 Capsule may be taken with or without food. Always take it exactly as prescribed by your doctor. Do not crush, cut or chew the capsules. Swallow it whole with water. You should take Lenava 10 Capsule at about the same time on the scheduled days.
Q. Can Lenava 10 Capsule be given to patients who are on dialysis?
Yes, Lenava 10 Capsule is given to dialysis patients after the dialysis is done. However, the doctor may adjust the dose if needed in patients undergoing.
Q. What are the side effects of Lenava 10 Capsule?
Lenava 10 Capsule may cause side effects which include diarrhea, constipation, stomach pain, loss of appetite, weight loss, weakness, dizziness, change in ability to taste, and pain or burning of the tongue, mouth, or throat. The medicine may also cause decreased sense of touch, burning or tingling in the hands or feet, difficulty falling asleep or staying asleep, depression, and joint, muscle, bone, or back pain. You may also experience sweating, dry skin, abnormal hair growth in women, uncontrollable shaking of a part of the body, decrease in sexual desire or ability or painful, frequent, or urgent urination. Tell your doctor if any of these symptoms are severe or do not go away.
Q. Can Lenava 10 Capsule cause cancer?
People with multiple myeloma (a form of cancer that begins in plasma cells, a type of white blood cell) who receive melphalan (chemotherapy) and a blood stem cell transplant with the addition of Lenava 10 Capsule have a higher risk of developing new cancers. These types of cancers may include certain blood cancers (acute myelogenous leukemia or AML) and a type of lymphoma called Hodgkin lymphoma. Talk to your doctor about your risk of developing new cancers if you are taking Lenava 10 Capsule.
Q. Do I need to get any blood tests done while on Lenava 10 Capsule?
Your doctor will ask you to have a blood test before treatment and every week for the first 8 weeks of treatment. You may need to continue taking the blood tests at least every month after treatment with Lenava 10 Capsule ends. Frequent blood tests are important as Lenava 10 Capsule may decrease the blood cells that help fight infection (white blood cells) and help the blood to clot (platelets).
Q. Do I need to use birth control methods while using Lenava 10 Capsule?
Women who can become pregnant must use two acceptable forms of birth control for 4 weeks before they begin taking Lenava 10 Capsule. Continue using contraceptives during your treatment, including the times when your doctor tells you to temporarily stop taking Lenava 10 Capsule, and for 4 weeks after your final dose. In men, Lenava 10 Capsule may pass into the semen while they are on treatment. Therefore, men must always use a latex condom every time they have sexual contact, even if they have had a vasectomy (surgery that prevents a man from causing a pregnancy). Use the contraceptive while you are taking Lenava 10 Capsule, during any breaks in your treatment, and for 4 weeks after your final dose.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1742.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 784-85.
- Lenalidomide. Summit, New Jersey: Celgene Corporation. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:
- LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012. Lenalidomide. [Updated 2022 Aug 30]. [Accessed 08 Jul. 2023]. (online) Available from:
- Lenalidomide Capsules [Package Insert]. Bangalore, India: Biocon Limited. [Accessed 08 Jul. 2023]. (online) Available from:
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Marketer details
Name: GLS Pharma Ltd.
Address: R-4, Khirki Main Road, Malviya Nagar New Delhi- 110 017, (India)
Country of origin: India
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