Lethyrox 25 Tablet is a medicine used to treat an underactive thyroid gland (hypothyroidism). It replaces the hormone which is not being produced by your thyroid gland in sufficient quantity and helps regulate your body’s energy and metabolism.

Before you start taking Lethyrox 25 Tablet, your doctor will do a blood test to see what dose you need. Once you start taking the medicine, you will have regular blood tests to see how well it is working, and the dose may be adjusted from time to time. It is best taken on an empty stomach before your first meal of the day. You should take this medicine regularly to get the maximum benefit. It may take several weeks before your symptoms start to improve. You may need to take it for the rest of your life. If you stop taking it, your symptoms are likely to come back.

The most common side effects of this medicine are caused by taking a higher dose than you need. Possible side effects include palpitations (irregular heartbeat), vomiting, anxiety, diarrhea, weight loss, tremors, increased appetite, and restlessness. Most side effects will disappear once you are on the right dose. Call your doctor straight away if you have a very high temperature, fast or irregular heart rate, low blood pressure, yellowness in the eye/skin, confusion, or fits.

Lethyrox 25 Tablet may cause weight loss but should not be prescribed or taken to treat obesity. If you become pregnant while taking this medicine, inform your doctor right away as the dose may have to be increased/readjusted. Many other drugs affect the way this medicine works. Ask your doctor for advice if you are taking any other medications.

Uses of Lethyrox Tablet

Treatment of Hypothyroidism

Benefits of Lethyrox Tablet

In Treatment of Hypothyroidism

Lethyrox 25 Tablet is a synthetic version of thyroxine, a hormone that is naturally produced in your body. When your body does not produce enough thyroxine, you get hypothyroidism. Some symptoms of hypothyroidism include tiredness, weight gain, and muscle aches. This medicine raises your hormone level to the right amount and helps you get rid of these symptoms. For most people, this is a lifelong medication and should not be discontinued without talking to your doctor.

It may take a while for this medicine to work properly. Your doctor may get regular blood tests done to determine the effectiveness of this medicine and to make sure that you are on the right dose.

Side effects of Lethyrox Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lethyrox

Palpitations
Vomiting
Anxiety
Diarrhea
Weight loss
Nervousness
Increased appetite
Tremors

How to use Lethyrox Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lethyrox 25 Tablet is to be taken empty stomach.

How Lethyrox Tablet works

Lethyrox 25 Tablet is a synthetic version of a hormone produced by the thyroid gland. It works by replacing the thyroid hormones that your thyroid gland cannot produce in a sufficient quantity, and relieves the symptoms of hypothyroidism (tiredness, weight gain, and depression).

Safety advice

Alcohol

SAFE

Consuming alcohol with Lethyrox 25 Tablet does not cause any harmful side effects.

Pregnancy

SAFE IF PRESCRIBED

Lethyrox 25 Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Lethyrox 25 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

SAFE

Lethyrox 25 Tablet does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Lethyrox 25 Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Lethyrox 25 Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Lethyrox Tablet?

If you miss a dose of Lethyrox 25 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Lethyrox 25 Tablet

₹0.82/Tablet

Thyronorm 25mcg Tablet

Abbott

₹1.59/tablet

94% costlier

Thyroxinol 25 Tablet

Knoll Pharmaceuticals Ltd

₹1.21/tablet

48% costlier

Thyrocip Tablet

Cipla Ltd

₹1.23/tablet

50% costlier

Eltroxin 25mcg Tablet

Glaxo SmithKline Pharmaceuticals Ltd

₹1.61/tablet

96% costlier

Thyroactiv 25 Tablet

Leeford Healthcare Ltd

₹1.21/tablet

48% costlier

View all substitutes

Quick tips

Lethyrox 25 Tablet should be taken on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
It may take 6 to 8 weeks to get the full effect.
For most people, Lethyrox 25 Tablet can be a lifelong medication. Do not discontinue it without discussing your doctor.
Inform your doctor if you have diarrhea, nervousness, irritability, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose.
Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine.
Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted.
Inform your doctor before changing the brand of Lethyrox 25 Tablet as all brands may not have the same effect.

Fact Box

Chemical Class

Iodinated amino acid derivative

Habit Forming

Therapeutic Class

HORMONES

Action Class

Thyroid hormones

Patient concerns

I have affect by hypothyroidism if there any problem to get pregnant

Dr. Satyam S. Bhavsar

Physician

yes, hypothyroidism may effect fertility.

I'm suffering from hypothyroidism

Dr. Deepak Kumar Soni

Ayurveda

https://goo.gl/forms/YhGqRXe7vppuodhT2 kindly share your detail for better treatment

FAQs

What should I do if I accidentally take more than the dose required?

An overdose of this medicine may cause nervousness, anxiety, rapid heartbeat, hand tremors, excessive sweating, weight loss, and sleep problems. You should immediately consult your doctor in case of an overdose.

How long do I need to take Lethyrox 25 Tablet?

You should take Lethyrox 25 Tablet as long as your doctor has recommended. Usually, it is prescribed for the long term and you may have to take it lifelong. Do not stop taking the medicine, as your symptoms of low levels of thyroid hormone may reoccur.

How should Lethyrox 25 Tablet be taken?

Take Lethyrox 25 Tablet exactly as advised by your doctor. Lethyrox 25 Tablet should be taken orally preferably before breakfast or as a first meal of the day. It should be swallowed whole with plenty of water.

Being a diabetic what should I be aware of while taking Lethyrox 25 Tablet?

Lethyrox 25 Tablet may raise blood sugar levels and may affect the working of other anti-diabetic medicines which you might be taking. Hence, dose adjustment may be required. Consult your doctor who will help you with dose management.

What does thyroxine do? Why is it important?

Thyroxine hormone controls how much energy your body uses. It plays an important role in regulating your body weight, muscle strength, body temperature, and even your mood. Along with that, it is important for your digestion, heart muscles, brain development, and bone health.

Does Lethyrox 25 Tablet affect contraception?

Oral birth control pills, which contain both estrogen and progesterone may reduce the amount of Lethyrox 25 Tablet in your body and therefore the dose of Lethyrox 25 Tablet may have to be increased.

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Related lab tests

Anti Thyroglobulin Antibody

Thyroid Function Test

Thyroid Profile Free

Thyroid Stimulating Hormone

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Brent GA, Koenig RJ. Thyroid and Anti-Thyroid Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1142-43.
Dong BJ, Greenspan FS. Thyroid & Antithyroid Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 674-75.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 796-98.
Levothyroxine sodium. East Sussex, UK: Custom Pharmaceuticals Ltd.; 2018. [Accessed 04 Apr. 2019] (online) Available from:
Levothyroxine. Bohemia, New York: Jerome Stevens Pharmaceuticals, Inc. [Accessed 04 Apr. 2019] (online) Available from:
Levothyroxine [Prescribing Information]. Morgantown, WV: Mylan Pharmaceuticals Inc.; 2022. [Accessed 07 Aug. 2023]. (online) Available from:

Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India

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