Lethyrox 50 Tablet
Prescription Required
Product introduction
Lethyrox 50 Tablet is a medicine used to treat an underactive thyroid gland (hypothyroidism). It replaces the hormone which is not being produced by your thyroid gland in sufficient quantity and helps regulate your body’s energy and metabolism.
Before you start taking Lethyrox 50 Tablet, your doctor will do a blood test to see what dose you need. Once you start taking the medicine, you will have regular blood tests to see how well it is working, and the dose may be adjusted from time to time. It is best taken on an empty stomach before your first meal of the day. You should take this medicine regularly to get the maximum benefit. It may take several weeks before your symptoms start to improve. You may need to take it for the rest of your life. If you stop taking it, your symptoms are likely to come back.
The most common side effects of this medicine are caused by taking a higher dose than you need. Possible side effects include palpitations (irregular heartbeat), vomiting, anxiety, diarrhea, weight loss, tremors, increased appetite, and restlessness. Most side effects will disappear once you are on the right dose. Call your doctor straight away if you have a very high temperature, fast or irregular heart rate, low blood pressure, yellowness in the eye/skin, confusion, or fits.
Lethyrox 50 Tablet may cause weight loss but should not be prescribed or taken to treat obesity. If you become pregnant while taking this medicine, inform your doctor right away as the dose may have to be increased/readjusted. Many other drugs affect the way this medicine works. Ask your doctor for advice if you are taking any other medications.
Before you start taking Lethyrox 50 Tablet, your doctor will do a blood test to see what dose you need. Once you start taking the medicine, you will have regular blood tests to see how well it is working, and the dose may be adjusted from time to time. It is best taken on an empty stomach before your first meal of the day. You should take this medicine regularly to get the maximum benefit. It may take several weeks before your symptoms start to improve. You may need to take it for the rest of your life. If you stop taking it, your symptoms are likely to come back.
The most common side effects of this medicine are caused by taking a higher dose than you need. Possible side effects include palpitations (irregular heartbeat), vomiting, anxiety, diarrhea, weight loss, tremors, increased appetite, and restlessness. Most side effects will disappear once you are on the right dose. Call your doctor straight away if you have a very high temperature, fast or irregular heart rate, low blood pressure, yellowness in the eye/skin, confusion, or fits.
Lethyrox 50 Tablet may cause weight loss but should not be prescribed or taken to treat obesity. If you become pregnant while taking this medicine, inform your doctor right away as the dose may have to be increased/readjusted. Many other drugs affect the way this medicine works. Ask your doctor for advice if you are taking any other medications.
Uses of Lethyrox Tablet
Side effects of Lethyrox Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lethyrox
- Palpitations
- Vomiting
- Anxiety
- Diarrhea
- Weight loss
- Nervousness
- Increased appetite
- Tremors
How to use Lethyrox Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lethyrox 50 Tablet is to be taken empty stomach.
How Lethyrox Tablet works
Lethyrox 50 Tablet is a synthetic version of a hormone produced by the thyroid gland. It works by replacing the thyroid hormones that your thyroid gland cannot produce in a sufficient quantity, and relieves the symptoms of hypothyroidism (tiredness, weight gain, and depression).
Safety advice
Alcohol
SAFE
Consuming alcohol with Lethyrox 50 Tablet does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Lethyrox 50 Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Lethyrox 50 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
SAFE
Lethyrox 50 Tablet does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Lethyrox 50 Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Lethyrox 50 Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take Lethyrox Tablet?
If you miss a dose of Lethyrox 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
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Quick tips
- Lethyrox 50 Tablet should be taken on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
- It may take 6 to 8 weeks to get the full effect.
- For most people, Lethyrox 50 Tablet can be a lifelong medication. Do not discontinue it without discussing your doctor.
- Inform your doctor if you have diarrhea, nervousness, irritability, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose.
- Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine.
- Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted.
- Inform your doctor before changing the brand of Lethyrox 50 Tablet as all brands may not have the same effect.
- Your doctor has prescribed Lethyrox 50 Tablet to replace the natural thyroid hormone that your own thyroid gland can no longer make.
- Lethyrox 50 Tablet should be taken on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
- It may take 6 to 8 weeks to get the full effect.
- For most people, Lethyrox 50 Tablet can be a lifelong medication. Do not discontinue it without discussing your doctor.
- Inform your doctor if you have diarrhea, nervousness, irritability, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose.
- Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine.
- Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted.
- Inform your doctor before changing the brand of Lethyrox 50 Tablet as all brands may not have the same effect.
Fact Box
Chemical Class
Iodinated amino acid derivative
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
Thyroid Hormones
Interaction with drugs
Taking Lethyrox with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Amiodarone may reduce blood levels of Thyroxine and its active form.
Do not consume Thyroxine with Amiodarone. If concurrent use is essential, your doctor may monitor your thyroid
Amiodarone may reduce blood levels of Thyroxine and its active form.
Do not consume Thyroxine with Amiodarone. If concurrent use is essential, your doctor may monitor your thyroid
Atazanavir may reduce the efficacy of Thyroxine.
If concurrent use is essential, please consult your doctor, they may monitor your thyroid function closely along with your overall
Thyroxine may increase the effect of Calcium.
Ensure a gap of at least 4 hours between taking Thyroxine and Calcium.
Concurrent use may increase the requirement of Thyroxine.
If concurrent use is essential, your doctor may monitor your thyroid functioning closely along with your overall treatmen
Patient concerns
User feedback
Patients taking Lethyrox 50 Tablet
Once A Day
99%
Twice A Week
1%
What are you using Lethyrox Tablet for?
Hypothyroidis*
100%
*Hypothyroidism
How much was the improvement?
Average
100%
FAQs
What should I do if I accidentally take more than the dose required?
An overdose of this medicine may cause nervousness, anxiety, rapid heartbeat, hand tremors, excessive sweating, weight loss, and sleep problems. You should immediately consult your doctor in case of an overdose.
How long do I need to take Lethyrox 50 Tablet?
You should take Lethyrox 50 Tablet as long as your doctor has recommended. Usually, it is prescribed for the long term and you may have to take it lifelong. Do not stop taking the medicine, as your symptoms of low levels of thyroid hormone may reoccur.
How should Lethyrox 50 Tablet be taken?
Take Lethyrox 50 Tablet exactly as advised by your doctor. Lethyrox 50 Tablet should be taken orally preferably before breakfast or as a first meal of the day. It should be swallowed whole with plenty of water.
Being a diabetic what should I be aware of while taking Lethyrox 50 Tablet?
Lethyrox 50 Tablet may raise blood sugar levels and may affect the working of other anti-diabetic medicines which you might be taking. Hence, dose adjustment may be required. Consult your doctor who will help you with dose management.
What does thyroxine do? Why is it important?
Thyroxine hormone controls how much energy your body uses. It plays an important role in regulating your body weight, muscle strength, body temperature, and even your mood. Along with that, it is important for your digestion, heart muscles, brain development, and bone health.
Does Lethyrox 50 Tablet affect contraception?
Oral birth control pills, which contain both estrogen and progesterone may reduce the amount of Lethyrox 50 Tablet in your body and therefore the dose of Lethyrox 50 Tablet may have to be increased.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Brent GA, Koenig RJ. Thyroid and Anti-Thyroid Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1142-43.
- Dong BJ, Greenspan FS. Thyroid & Antithyroid Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 674-75.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 796-98.
- Levothyroxine sodium. East Sussex, UK: Custom Pharmaceuticals Ltd.; 2018. [Accessed 04 Apr. 2019] (online) Available from:
- Levothyroxine. Bohemia, New York: Jerome Stevens Pharmaceuticals, Inc. [Accessed 04 Apr. 2019] (online) Available from:
- Levothyroxine [Prescribing Information]. Morgantown, WV: Mylan Pharmaceuticals Inc.; 2022. [Accessed 07 Aug. 2023]. (online) Available from:
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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