Letoval Tablet
Prescription Required
Product introduction
Letoval Tablet helps treat breast cancer in post-menopausal women. It may be used alone or with other treatments, such as surgery or radiation. It can also be used in patients with advanced breast cancer to stop the tumor from spreading to other parts of the body.
Letoval Tablet can be taken with or without food. Take it in the dose and duration prescribed by the doctor to get the most benefit. The dose and frequency depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed.
The most common side effects of this medicine include hot flashes, fatigue, increased sweating, and increased level of cholesterol (hypercholesterolemia). If these bother you or appear serious, let your doctor know. Your doctor may suggest ways to prevent or reduce these.
Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, or have a history of osteoporosis (thinning or wasting of bones). Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check for vitamin D level or bone density before and during treatment.
Uses of Letoval Tablet
Side effects of Letoval Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Letoval
- Night sweats
- Bone pain
- Cough
- Shortness of breath
- Fatigue
- Weight gain
- Hot flushes
- Edema (swelling)
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Diaphoresis
- Bone fracture
- Hypercholesterolemia (high cholesterol)
- Joint pain
- Back pain
- Weakness
- Dizziness
- Nausea
- Osteoporosis
- Joint inflammation
How to use Letoval Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Letoval Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Letoval Tablet works
Letoval Tablet is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrogen can slow down or stop the growth of some breast cancers that need estrogen to grow.
Safety advice
Alcohol
SAFE
Consuming alcohol with Letoval Tablet does not cause any harmful side effects.
Pregnancy
UNSAFE
Letoval Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Letoval Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Letoval Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Letoval Tablet is safe to use in patients with kidney disease. No dose adjustment of Letoval Tablet is recommended.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.
Liver
CAUTION
Letoval Tablet should be used with caution in patients with liver disease. Dose adjustment of Letoval Tablet may be needed. Please consult your doctor.
What if you forget to take Letoval Tablet?
If you miss a dose of Letoval Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
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Quick tips
- You have been prescribed Letoval Tablet for the treatment of breast cancer.
- It can be taken with or without food.
- Do not drive or do anything requiring concentration until you know how Letoval Tablet affects you.
- It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
- Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Letoval Tablet can alter their levels.
- Do not take Letoval Tablet if you are pregnant or breastfeeding
Fact Box
Chemical Class
Diphenylmethane Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Aromatase Inhibitors
Interaction with drugs
Taking Letoval with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Allylestrenol may reduce the efficacy of Letrozole.
Do not consume Letrozole with Allylestrenol if you have or had breast cancer. If essential, consult your doctor.
Dehydroepiandrosterone (Micronized) may reduce the efficacy of Letrozole.
Do not consume Letrozole with Dehydroepiandrosterone (Micronized) if you have or had breast cancer. If es
Desogestrel may reduce the efficacy of Letrozole.
Do not consume Letrozole with Desogestrel if you have or had breast cancer. If essential, consult your doctor.
Tamoxifen may reduce blood levels of Letrozole.
Do not consume Tamoxifen with Letrozole. If concurrent use is essential, please consult your doctor.
Patient concerns
User feedback
Patients taking Letoval Tablet
Once A Day
100%
What are you using Letoval Tablet for?
Others
92%
Breast cancer
7%
Infertility
1%
How much was the improvement?
Poor
42%
Average
33%
Excellent
25%
What were the side-effects while using Letoval Tablet?
No Side Effec*
72%
Fatigue
20%
Hot flashes
4%
Increased swe*
4%
*No Side Effect, Increased sweating
How do you take Letoval Tablet?
With food
83%
With or witho*
17%
*With or without food
Please rate Letoval Tablet on price
Expensive
47%
Average
39%
Not Expensive
14%
FAQs
Why have I been prescribed Letoval Tablet?
Letoval Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy.
How does Letoval Tablet work?
Letoval Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent cancer from growing.
For how long should I take Letoval Tablet?
If the breast tumor is in the advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letoval Tablet till the tumor shows progression. In cases where Letoval Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until the tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Letoval Tablet followed by 3 years of tamoxifen.
If I am taking irbesartan to control my blood pressure, can I take Letoval Tablet?
Yes, you can take irbesartan and Letoval Tablet together. However, be careful and keep a regular check on your blood pressure since Letoval Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.
Does Letoval Tablet affect vision?
Although it is very uncommon, Letoval Tablet may cause a cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.
My friend who is taking Letoval Tablet often sweats a lot. Is it because of Letoval Tablet?
This could be a sign of hot flushes which is a very common side effect of Letoval Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letoval Tablet. However, in some people, the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.
What are the serious side effects of Letoval Tablet?
The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letoval Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and severe skin reactions.
Does Letoval Tablet cause bone loss?
Letoval Tablet may cause thinning or wasting of your bones (osteoporosis), which is due to the decrease in estrogen levels in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during and after treatment.
Can I take Letoval Tablet for induction of ovulation in anovulatory infertility?
As per the Ministry of Health and Family Welfare, Letoval Tablet is restricted for use in induction of ovulation in anovulatory infertility.
Why have I been prescribed Letoval Tablet?
Letoval Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy.
How does Letoval Tablet work?
Letoval Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent the cancer from growing.
For how long should I take Letoval Tablet?
If the breast tumor is in advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letoval Tablet till the tumor shows progression. In cases where Letoval Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Letoval Tablet followed by 3 years of tamoxifen.
If I am taking irbesartan to control my blood pressure, can I take Letoval Tablet?
Yes, you can take irbesartan and Letoval Tablet together. However, be careful and keep a regular check on your blood pressure since Letoval Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.
Does Letoval Tablet affect vision?
Although it is very uncommon but Letoval Tablet may cause cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.
My friend who is taking Letoval Tablet often sweats a lot. Is it because of Letoval Tablet?
This could be a sign of hot flushes which is a very common side effect of Letoval Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letoval Tablet. However, in some people the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.
What are the serious side effects of Letoval Tablet?
The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letoval Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis and severe skin reactions.
Does Letoval Tablet cause bone loss?
Letoval Tablet may cause thinning or wasting of your bones (osteoporosis), which is due to the decrease in estrogen levels in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during and after treatment.
Can I take Letoval Tablet for induction of ovulation in anovulatory infertility?
As per the Ministry of Health and Family Welfare, Letoval Tablet is restricted for use in induction of ovulation in anovulatory infertility.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1762.
- Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 786-87.
- Letrozole. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
- National Health Service. Letrozole. [Last Reviewed: 21 Jul 2020]. [Accessed 08 Jul. 2023]. (online) Available from:
- Letrozole [Package Insert]. Mumbai, India: HOPE Lifecare. [Accessed 08 Jul. 2023]. (online) Available from:
- Letrozole [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2020. [Accessed 08 Jul. 2023]. (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
Expires on or after: August, 2025
A licensed vendor partner from your nearest location will deliver Letoval Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: August, 2025
A licensed vendor partner from your nearest location will deliver Letoval Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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