Letrablu 2.5mg Tablet
Prescription Required
Product introduction
Letrablu 2.5mg Tablet helps treat breast cancer in post-menopausal women. It may be used alone or with other treatments, such as surgery or radiation. It can also be used in patients with advanced breast cancer to stop the tumor from spreading to other parts of the body.
Letrablu 2.5mg Tablet can be taken with or without food. Take it in the dose and duration prescribed by the doctor to get the most benefit. The dose and frequency depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed.
The most common side effects of this medicine include hot flashes, fatigue, increased sweating, and increased level of cholesterol (hypercholesterolemia). If these bother you or appear serious, let your doctor know. Your doctor may suggest ways to prevent or reduce these.
Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, or have a history of osteoporosis (thinning or wasting of bones). Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check for vitamin D level or bone density before and during treatment.
Uses of Letrablu Tablet
Side effects of Letrablu Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Letrablu
- Night sweats
- Bone pain
- Cough
- Shortness of breath
- Fatigue
- Weight gain
- Hot flushes
- Edema (swelling)
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Diaphoresis
- Bone fracture
- Hypercholesterolemia (high cholesterol)
- Joint pain
- Back pain
- Weakness
- Dizziness
- Nausea
- Osteoporosis
- Joint inflammation
How to use Letrablu Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Letrablu 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Letrablu Tablet works
Letrablu 2.5mg Tablet is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrogen can slow down or stop the growth of some breast cancers that need estrogen to grow.
Safety advice
Alcohol
SAFE
Consuming alcohol with Letrablu 2.5mg Tablet does not cause any harmful side effects.
Pregnancy
UNSAFE
Letrablu 2.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Letrablu 2.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Letrablu 2.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Letrablu 2.5mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Letrablu 2.5mg Tablet is recommended.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.
Liver
CAUTION
Letrablu 2.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Letrablu 2.5mg Tablet may be needed. Please consult your doctor.
What if you forget to take Letrablu Tablet?
If you miss a dose of Letrablu 2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Letrablu 2.5mg Tablet
₹30.8/Tablet
Letroz Tablet
Sun Pharmaceutical Industries Ltd
₹32.83/tablet
7% costlier
Oncolet 2.5mg Tablet
Biochem Pharmaceutical Industries
₹4.91/tablet
84% cheaper
Fempro Tablet
Cipla Ltd
₹7.16/tablet
77% cheaper
Femara 2.5mg Tablet
Novartis India Ltd
₹31.5/tablet
2% costlier
Letroz 2.5mg Tablet
Sun Pharmaceutical Industries Ltd
₹20.2/tablet
34% cheaper
Quick tips
- You have been prescribed Letrablu 2.5mg Tablet for the treatment of breast cancer.
- It can be taken with or without food.
- Do not drive or do anything requiring concentration until you know how Letrablu 2.5mg Tablet affects you.
- It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
- Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Letrablu 2.5mg Tablet can alter their levels.
- Do not take Letrablu 2.5mg Tablet if you are pregnant or breastfeeding
Fact Box
Chemical Class
Diphenylmethane Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Aromatase Inhibitors
Interaction with drugs
Taking Letrablu with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Levonorgestrel (intrauterine delivery system) may reduce the efficacy of Letrozole.
Do not consume Letrozole with Levonorgestrel (intrauterine delivery system) if you have or had
Lynestrenol may reduce the efficacy of Letrozole.
Do not consume Letrozole with Lynestrenol if you have or had breast cancer. If essential, consult your doctor.
Medroxyprogesterone acetate may reduce the efficacy of Letrozole.
Do not consume Letrozole with Medroxyprogesterone acetate if you have or had breast cancer. If essential, consult
Medroxyprogesterone acetate may reduce the efficacy of Letrozole.
Do not consume Letrozole with Medroxyprogesterone acetate if you have or had breast cancer. If essential, consult
Tamoxifen may reduce blood levels of Letrozole.
Do not consume Tamoxifen with Letrozole. If concurrent use is essential, please consult your doctor.
Patient concerns
FAQs
Why have I been prescribed Letrablu 2.5mg Tablet?
Letrablu 2.5mg Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy.
How does Letrablu 2.5mg Tablet work?
Letrablu 2.5mg Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent cancer from growing.
For how long should I take Letrablu 2.5mg Tablet?
If the breast tumor is in the advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letrablu 2.5mg Tablet till the tumor shows progression. In cases where Letrablu 2.5mg Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until the tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Letrablu 2.5mg Tablet followed by 3 years of tamoxifen.
If I am taking irbesartan to control my blood pressure, can I take Letrablu 2.5mg Tablet?
Yes, you can take irbesartan and Letrablu 2.5mg Tablet together. However, be careful and keep a regular check on your blood pressure since Letrablu 2.5mg Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.
Does Letrablu 2.5mg Tablet affect vision?
Although it is very uncommon, Letrablu 2.5mg Tablet may cause a cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.
My friend who is taking Letrablu 2.5mg Tablet often sweats a lot. Is it because of Letrablu 2.5mg Tablet?
This could be a sign of hot flushes which is a very common side effect of Letrablu 2.5mg Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letrablu 2.5mg Tablet. However, in some people, the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.
What are the serious side effects of Letrablu 2.5mg Tablet?
The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letrablu 2.5mg Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and severe skin reactions.
Does Letrablu 2.5mg Tablet cause bone loss?
Letrablu 2.5mg Tablet may cause thinning or wasting of your bones (osteoporosis), which is due to the decrease in estrogen levels in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during and after treatment.
Can I take Letrablu 2.5mg Tablet for induction of ovulation in anovulatory infertility?
As per the Ministry of Health and Family Welfare, Letrablu 2.5mg Tablet is restricted for use in induction of ovulation in anovulatory infertility.
Why have I been prescribed Letrablu 2.5mg Tablet?
Letrablu 2.5mg Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy.
How does Letrablu 2.5mg Tablet work?
Letrablu 2.5mg Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent the cancer from growing.
For how long should I take Letrablu 2.5mg Tablet?
If the breast tumor is in advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letrablu 2.5mg Tablet till the tumor shows progression. In cases where Letrablu 2.5mg Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Letrablu 2.5mg Tablet followed by 3 years of tamoxifen.
If I am taking irbesartan to control my blood pressure, can I take Letrablu 2.5mg Tablet?
Yes, you can take irbesartan and Letrablu 2.5mg Tablet together. However, be careful and keep a regular check on your blood pressure since Letrablu 2.5mg Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.
Does Letrablu 2.5mg Tablet affect vision?
Although it is very uncommon but Letrablu 2.5mg Tablet may cause cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.
My friend who is taking Letrablu 2.5mg Tablet often sweats a lot. Is it because of Letrablu 2.5mg Tablet?
This could be a sign of hot flushes which is a very common side effect of Letrablu 2.5mg Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letrablu 2.5mg Tablet. However, in some people the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.
What are the serious side effects of Letrablu 2.5mg Tablet?
The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letrablu 2.5mg Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis and severe skin reactions.
Does Letrablu 2.5mg Tablet cause bone loss?
Letrablu 2.5mg Tablet may cause thinning or wasting of your bones (osteoporosis), which is due to the decrease in estrogen levels in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during and after treatment.
Can I take Letrablu 2.5mg Tablet for induction of ovulation in anovulatory infertility?
As per the Ministry of Health and Family Welfare, Letrablu 2.5mg Tablet is restricted for use in induction of ovulation in anovulatory infertility.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1762.
- Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 786-87.
- Letrozole. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
- National Health Service. Letrozole. [Last Reviewed: 21 Jul 2020]. [Accessed 08 Jul. 2023]. (online) Available from:
- Letrozole [Package Insert]. Mumbai, India: HOPE Lifecare. [Accessed 08 Jul. 2023]. (online) Available from:
- Letrozole [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2020. [Accessed 08 Jul. 2023]. (online) Available from:
Marketer details
Name: Bluewaterresearch
Address: plot no. 11-12, sector 25-d, danik bhaskar building, chandigarh, 160014
Country of origin: India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Letrablu 2.5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Letrablu 2.5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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