Leuprolide 3.75mg Depot One Combipack
Prescription Required
Product introduction
Leuprolide 3.75mg Depot One Combipack is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty).
Leuprolide 3.75mg Depot One Combipack is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.
Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Leuprolide Kit
- Prostate cancer
- Endometriosis
- Uterine fibroids
- Precocious puberty (premature puberty)
- Female infertility
Side effects of Leuprolide Kit
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Leuprolide
- Decreased libido
- Testicular atrophy
- Increased sweating
- Fatigue
- Muscle weakness
- Erectile dysfunction
- Hot flashes
How to use Leuprolide Kit
Take this medicine in the dose and duration as advised by your doctor. Check the label before use.
How Leuprolide Kit works
Leuprolide 3.75mg Depot One Combipack reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Leuprolide 3.75mg Depot One Combipack also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Leuprolide 3.75mg Depot One Combipack. Please consult your doctor.
Pregnancy
UNSAFE
Leuprolide 3.75mg Depot One Combipack is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Leuprolide 3.75mg Depot One Combipack during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Leuprolide 3.75mg Depot One Combipack may cause side effects which could affect your ability to drive.
Do not drive or operate machinery if you experience drowsiness, dizziness or visual disturbances whilst being treated with Leuprolide 3.75mg Depot One Combipack.
Do not drive or operate machinery if you experience drowsiness, dizziness or visual disturbances whilst being treated with Leuprolide 3.75mg Depot One Combipack.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Leuprolide 3.75mg Depot One Combipack in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Leuprolide 3.75mg Depot One Combipack in patients with liver disease. Please consult your doctor.
What if you forget to take Leuprolide Kit?
If you miss a dose of Leuprolide 3.75mg Depot One Combipack, please consult your doctor.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Leuprolide 3.75mg Depot One Combipack helps in the treatment of locally advanced or metastatic prostate cancer.
- It may also be used to treat endometriosis and uterine fibroids.
- It is given as an injection either under the skin or into a muscle.
- It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.
- It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment.
- Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.
- Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.
Fact Box
Chemical Class
GNRH Analogue
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Gonadotropin-releasing hormone (GnRH) Agonists
Patient concerns
User feedback
Patients taking Leuprolide 3.75mg Depot One Combipack
Once A Month
73%
Once A Week
23%
Once A Day
4%
What are you using Leuprolide Kit for?
Prostate canc*
100%
*Prostate cancer
How much was the improvement?
Excellent
100%
FAQs
Is Leuprolide 3.75mg Depot One Combipack a chemotherapy medicine?
No, Leuprolide 3.75mg Depot One Combipack is not a chemotherapy medicine. Leuprolide 3.75mg Depot One Combipack is a synthetic hormone analogue medicine which is used for the treatment of hormone-dependent conditions in men and women.
Does Leuprolide 3.75mg Depot One Combipack stop periods?
Yes, the periods tend to stop while taking Leuprolide 3.75mg Depot One Combipack injections as this medicine alters the reproductive hormones in females. Sometimes, there can be vaginal bleeding in few cases. If this occurs, please contact your doctor to get yourself assessed and follow the direction of your doctor.
Is Leuprolide 3.75mg Depot One Combipack a hormonal medicine and can it be given in pregnancy?
Yes, Leuprolide 3.75mg Depot One Combipack is a hormonal medicine which alters the reproductive hormones when given in females. This medication is not recommended for use in women who are or may become pregnant because this can harm the fetus in the womb. Using this medicine during pregnancy may also lead to abortion of the baby. Do inform your doctor if you are pregnant or are planning to get pregnant before starting this medication.
Can taking Leuprolide 3.75mg Depot One Combipack affect my bones?
Yes, there are chances of Leuprolide 3.75mg Depot One Combipack affecting your bones. Using Leuprolide 3.75mg Depot One Combipack may cause a decrease in bone mineral density and make the bones weaker. In women, bone density should be assessed before starting the treatment. Special care and monitoring should be done in women with increased risk of osteoporosis. If at all needed, additional medicines may be given to prevent the development of osteoporosis in patients with decreased bone mineral density.
Can Leuprolide 3.75mg Depot One Combipack cause diabetes or increased blood sugar?
Yes, Leuprolide 3.75mg Depot One Combipack may cause an increase in blood sugar levels, worsening the blood glucose control in patients with diabetes. It can even increase the risk of developing diabetes. Therefore, you must monitor the blood glucose and/or glycosylated hemoglobin (HbA1c) from time to time to keep a track of the glucose control and inform your doctor in case you develop any problem. Diabetic patients when prescribed this medication should monitor the sugar levels more frequently while taking this treatment.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 959.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 787-88.
- Leuprorelin acetate. Wooburn Green, High Wycombe: Takeda UK Ltd.; 2011 [revised 11 Jun. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
- Leuprolide Leuprorelin acetate. Fort Collins: TOLMAR Inc.; 2002 [revised Feb. 2016]. [Accessed 26 Mar. 2019] (online) Available from:
- Leuprolide acetate [Prescribing Information]. Fort Collins, CO: TOLMAR Therapeutics, Inc.; 2016. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India
Expires on or after: February, 2025
A licensed vendor partner from your nearest location will deliver Leuprolide 3.75mg Depot One Combipack. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: February, 2025
A licensed vendor partner from your nearest location will deliver Leuprolide 3.75mg Depot One Combipack. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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