Libure 135mg Tablet is a prescription medicine used to treat and relieve symptoms of irritable bowel syndrome such as stomach pain and spasm, cramps in the abdomen, gas, bloating, and changes in bowel habits. This medicine relaxes muscles of the intestine and relieves spasms.

Libure 135mg Tablet should be taken in a dose and duration as advised by your doctor. It is swallowed whole with a drink of water preferably 20 minutes before a meal to relieve or reduce post-meal symptoms. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Remember following lifestyle modifications like having a fiber-rich diet, increase fluid intake and regular exercise can help you to get better results.

This medicine has very less or minimal side effects but it may cause skin rash, fainting, or angioedema sometimes. Be cautious as it is important to stop the medication and inform the doctor if you encounter difficulty in breathing or swelling of the face, neck, tongue, or throat.

Before taking this medicine, you should let your doctor know if you have liver and kidney problems. Pregnant or breastfeeding women should also consult their doctor before taking this medicine.

Uses of Libure Tablet

Irritable bowel syndrome

Side effects of Libure Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Libure

Fainting
Skin rash
Angioedema (swelling of deeper layers of skin)

How to use Libure Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Libure 135mg Tablet is to be taken empty stomach.

How Libure Tablet works

Libure 135mg Tablet relaxes the muscles of the intestine and relieves spasm.

Safety advice

Alcohol

SAFE

Consuming alcohol with Libure 135mg Tablet does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Libure 135mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Libure 135mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Libure 135mg Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Libure 135mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Libure 135mg Tablet may not be needed in these patients. Please consult your doctor.
Caution is advised in patients with severe kidney disease.

Liver

SAFE IF PRESCRIBED

Libure 135mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Libure 135mg Tablet may not be needed in these patients. Please consult your doctor.
Caution is advised in patients with severe liver disease.

What if you forget to take Libure Tablet?

If you miss a dose of Libure 135mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Libure 135mg Tablet

₹6.87/Tablet

Morease Tablet

Dr Reddy's Laboratories Ltd

₹12.6/tablet

83% costlier

Colospa Tablet

Abbott

₹26/tablet

278% costlier

Mebaspa Tablet

USV Ltd

₹9.22/tablet

34% costlier

Fibrispa Tablet

Fibrica Healthcare Pvt Ltd

₹12.4/tablet

80% costlier

Mebaus 135 Tablet

Care Formulation Labs Pvt Ltd

₹13/tablet

89% costlier

View all substitutes

Quick tips

Libure 135mg Tablet relieves symptoms of irritable bowel syndrome such as abdominal pain and cramps, bloating, flatulence and diarrhea alternating with constipation.
Take it 20 minutes before a meal to relieve or reduce post meal symptoms.
Talk to your doctor if your symptoms do not get better within two weeks of taking Libure 135mg Tablet, or get worse at any time.
Stop taking Libure 135mg Tablet and consult a doctor if you experience difficulty in breathing or swelling of face, neck, tongue or throat.
Do not stop taking the tablets without talking to your doctor, even if you feel better.
Libure 135mg Tablet relieves symptoms of irritable bowel syndrome such as abdominal pain and cramps, bloating, flatulence and diarrhea alternating with constipation.
Take it 20 minutes before a meal to relieve or reduce post meal symptoms.
Talk to your doctor if your symptoms do not get better within two weeks of taking Libure 135mg Tablet, or get worse at any time.
Stop taking Libure 135mg Tablet and consult a doctor if you experience difficulty in breathing or swelling of face, neck, tongue or throat.
Do not stop taking the tablets without talking to your doctor, even if you feel better.

Fact Box

Chemical Class

P-Methoxybenzoic Acids and Derivatives

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Antispasmodics (IBD)

Patient concerns

Restless leg syndrome with irritable bowel syndrome

Dr. Pushkar Mani

Physician

take cobadex czs once daily for 1 monthevion 400 mg once daily for 1 month

I have irritable bowel syndrome

Dr. Deepak Kumar Soni

Ayurveda

https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks

User feedback

What are you using Libure Tablet for?

Irritable bow*

100%

*Irritable bowel syndrome

How much was the improvement?

Poor

100%

How do you take Libure Tablet?

With food

100%

Please rate Libure 135mg Tablet on price

Not Expensive

100%

FAQs

What is Libure 135mg Tablet/Colospa/Colospa retard/ Mebaspa/Mebiz-SR/Morease used for?

Colospa/Colospa retard/ Mebaspa/Mebiz-SR/Morease are all trade name for the active medicine Libure 135mg Tablet. It is mainly used to treat and relieve symptoms of inflammatory bowel syndrome such as cramps in the abdomen, pain, gas, bloating and changes in bowel habits

Can Libure 135mg Tablet be used for period pain?

Libure 135mg Tablet mainly acts on the smooth muscles of the intestine. Hence, it is used to relieve cramps or spasms of the stomach and intestines (gut). It is particularly useful in treating irritable bowel syndrome (IBS) and similar conditions. It is not known whether it can be used for period pain

Can I take Libure 135mg Tablet with buscopan?

Buscopan contains butylscopolamine which is also an antispasmodic like Libure 135mg Tablet. Taking Libure 135mg Tablet and buscopan together will provide added effect, but can cause additive side-effects. Consult your doctor before taking Libure 135mg Tablet and buscopan together

Can I take mebeverine with Omeprazole/Lansoprazole?

There are no known serious drug interactions between mebeverine and omeprazole/lansoprazole. Consult your doctor about all medications currently taken before starting and while on mebeverine

Can I take Libure 135mg Tablet with Imodium/Loperamide?

There are no known serious drug interactions between Libure 135mg Tablet and Imodium/ Loperamide. Consult your doctor about all medications currently taken before starting and while on mebeverine

Can I take Libure 135mg Tablet with paracetamol/ Co codamol?

There are no known serious drug interactions between Libure 135mg Tablet and paracetamol and co codamol preparation which contains codeine with paracetamol. Consult your doctor about all medications currently taken before starting and while on mebeverine

Can I take Libure 135mg Tablet with antibiotics?

There are no known serious drug interactions between Libure 135mg Tablet and antibiotics. Consult your doctor about all medications currently taken before starting and while on Libure 135mg Tablet

Is Libure 135mg Tablet a laxative?

No, Libure 135mg Tablet is not a laxative; it belongs to a group of medicines called antispasmodics. It acts as a direct relaxant of the smooth muscles of the gut and relieves painfull contractions

Does Libure 135mg Tablet help constipation or stop diarrhea?

Libure 135mg Tablet may cause constipation; however, it has no known effects on stopping diarrhea

Does Libure 135mg Tablet reduce bloating?

Yes, Libure 135mg Tablet reduces all symptoms of inflammatory bowel syndrome such as abdominal cramps, pain, gas, and bloating

Does Libure 135mg Tablet affect pill/contraceptive pill?

No, there are no known interactions between Libure 135mg Tablet and contraceptive pills. Consult your doctor about all medications currently taken before starting and while on Libure 135mg Tablet

Is Libure 135mg Tablet a prescription /over the counter medicine?

Libure 135mg Tablet is available over the counter. However, do not self-medicate and consult your doctor about your symptoms before taking Libure 135mg Tablet

How long can I take Libure 135mg Tablet for?

Take Libure 135mg Tablet as directed by your doctor.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Mebeverine [New Zealand Data Sheet]. Wellington, New Zealand: Arrotex Pharmaceuticals (NZ) Limited; 2023. [Accessed 11 Jul. 2023]. (online) Available from:
Mebeverine hydrochloride [Patient Information Leaflet]. Constantia Kloof, South Africa: Abbott Laboratories S.A. (Pty) Ltd.; 2023. [Accessed 11 Jul. 2023]. (online) Available from:
National Health Services. How and when to take mebeverine. [Last reviewed: 17 Feb. 2023]. [Accessed 11 Jul. 2023]. (online) Available from:
Central Drugs Standard Control Organisation. Mebeverine. [Accessed 11 Jul. 2023]. (online) Available from:

Marketer details

Name: Aamorb Pharmaceuticals Pvt Ltd

Address: ug-47-48, bansi plaza, 581/5, mahatma gandhi rd, near indraprastha tower, new palasia, indore, madhya pradesh 452001

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.