Lopinovir R 50mg/200mg Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).

Lopinovir R 50mg/200mg Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine should be taken with food for better efficacy. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine.

The most common side effects of this medicine are diarrhea, nausea, vomiting, and increased blood fat levels (hypertriglyceridemia and hypercholesterolemia). These side effects are generally temporary, but if they persist or become serious inform your doctor. Drinking plenty of fluid can help you to cope up with these side effects, so stay hydrated. In addition to that, avoid alcohol consumption as it may increase the intensity of the side effects.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular laboratory tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.

Uses of Lopinovir R Tablet

HIV infection

Benefits of Lopinovir R Tablet

In HIV infection

Lopinovir R 50mg/200mg Tablet prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life.
It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.

Side effects of Lopinovir R Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lopinovir R

Taste change
Headache
Nausea
Vomiting
Diarrhea
Stomach pain
Increased liver enzymes
Increased blood lipid level
Peripheral neuropathy (tingling and numbness of feet and hand)

How to use Lopinovir R Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lopinovir R 50mg/200mg Tablet is to be taken with food.

How Lopinovir R Tablet works

Lopinovir R 50mg/200mg Tablet is a combination of two anti-HIV medicines: Ritonavir and Lopinavir. They work by interfering with an enzyme (protease), which is required by HIV-infected cells to make new viruses. This stops the production of new viruses.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Lopinovir R 50mg/200mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Lopinovir R 50mg/200mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Lopinovir R 50mg/200mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Lopinovir R 50mg/200mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Lopinovir R 50mg/200mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Lopinovir R 50mg/200mg Tablet may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Lopinovir R 50mg/200mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Lopinovir R 50mg/200mg Tablet may be needed. Please consult your doctor.

What if you forget to take Lopinovir R Tablet?

If you miss a dose of Lopinovir R 50mg/200mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Lopinovir R 50mg/200mg Tablet

₹48.42/Tablet

Luprareg 50mg/200mg Tablet

Macleods Pharmaceuticals Pvt Ltd

₹45.04/mg of tablet

7% cheaper

Emletra 50mg/200mg Tablet

Emcure Pharmaceuticals Ltd

₹50.49/tablet

4% costlier

Ritoford 50mg/200mg Tablet

Johnlee Pharmaceuticals Pvt Ltd

₹45.28/tablet

6% cheaper

Hivus-LR 50mg/200mg Tablet

Veritaz Healthcare Ltd

₹47.9/tablet

1% cheaper

Lopimune Tablet

Cipla Ltd

₹46.45/tablet

4% cheaper

View all substitutes

Quick tips

Lopinovir R 50mg/200mg Tablet is a combination medicine which slows down or stops the progression of HIV infection in the body.
Take it with food, preferably at the same time each day.
Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
It may cause weight gain and weakening of your bones. Eat healthy, exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
Do not stop taking Lopinovir R 50mg/200mg Tablet without your doctor’s advice.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner

hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero

Dr. Atula Gupta

Dermatology

You still need to be on ART even if the viral load is undetectable

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Ciplamed. Ritonavir+Lopinavir. [Accessed on 10 Apr. 2019 ] (online) Available from:
Ritonavir+Lopinavir. North Chicago, Illinois: Abbott Laboratories; 2010. [Accessed 10 Apr. 2019] (online) Available from:
Ritonavir/Lopinavir. Maidenhead, Berkshire: AbbVie Ltd.; 2001 [revised 25 Oct. 2018]. [Accessed 10 Apr. 2019] (online) Available from:
Ritonavir+Lopinavir. Barceloneta, Puerto Rico: AbbVie Ltd.; 2000 [revised Nov. 2016]. [Accessed 10 Apr. 2019] (online) Available from:

Marketer details

Name: Sentosa Geigy (India) Labs Limited

Address: M-10, Badli Industrial Estate, Phase-1, Delhi - 110042

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.