Makdril 1mg Injection
Prescription Required
Product introduction
Makdril 1mg Injection is used in the treatment of life-threatening emergencies like severe allergic reaction and cardiac arrest. It rapidly relieves breathlessness and wheezing by relaxing the airways. It also stimulates the heart and increases the blood pressure.
Makdril 1mg Injection also improves the swelling of face or tongue and hives seen in allergic reaction. It is given under the supervision of a doctor. Doctor may closely monitor your blood pressure, heart rate or ECG till you became stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
Common side effects associated with this medicine includes headache, restlessness, tremor, and palpitations. This medicine is used with caution for some people. Thus, if possible inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Makdril 1mg Injection also improves the swelling of face or tongue and hives seen in allergic reaction. It is given under the supervision of a doctor. Doctor may closely monitor your blood pressure, heart rate or ECG till you became stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
Common side effects associated with this medicine includes headache, restlessness, tremor, and palpitations. This medicine is used with caution for some people. Thus, if possible inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Uses of Makdril Injection
Benefits of Makdril Injection
In Severe allergic reactions
Makdril 1mg Injection is used along with emergency medical treatment to treat life-threatening allergic reactions caused by insect bites or stings, foods, medications, latex, and other causes. It reduces allergic reactions by reducing inflammatory response caused by the release of a chemical called histamine, that is responsible for various symptoms of allergic reactions like shortness of breath, hives, swelling, inflammation etc.
In Cardiac arrest
Makdril 1mg Injection contains a hormone called adrenaline, that stimulates the heart and promotes blood flow. It is a proven life-saving treatment for people whose heart s have stopped working all of a sudden due to an emergency condition called cardiac arrest. Its action is fast though it has a very short duration of action. It is given in an emergency condition to save life by a trained healthcare professional only.
Side effects of Makdril Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Makdril
- Headache
- Palpitations
- Tremors
How to use Makdril Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Makdril Injection works
Adrenaline is an alpha- and beta-adrenergic agonist. It relaxes muscles in your lungs and relieves spasm, wheezing, and shortness of breath that occurs during a severe allergic reaction (anaphylaxis).
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Makdril 1mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Makdril 1mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Makdril 1mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Makdril 1mg Injection does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Makdril 1mg Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Makdril 1mg Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Makdril Injection?
If you miss a dose of Makdril 1mg Injection, please consult your doctor.\n
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Quick tips
- It is usually given as an injection into your muscle. In cases of medical emergencies, it may be given through a vein.
- It may cause dizziness. Do not drive or anything requiring mental focus until you know how Makdril 1mg Injection affects you.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Fact Box
Chemical Class
Catecholamines
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Sympathomimetics agonist
Patient concerns
FAQs
Q. Where is Makdril 1mg Injection injected?
Makdril 1mg Injection should be injected only in the middle of the outer side of the thigh, and can be injected through clothing if necessary in an emergency.
Q. Which areas of the body Makdril 1mg Injection should not be given?
It should not be injected into a vein or into the muscles of your buttocks, since it may not work. Accidentally injecting this medicine into your hands or feet may result in a loss of blood flow to those areas, and resulting in numbness.
Q. When Makdril 1mg Injection should not be given?
This medicine should be avoided if you are suffering from any infection, disease, or tumor of the brain, history of heart disease (especially increased heart rate), or in cases of atherosclerosis (narrowing of your blood vessels).
Q. When should I call my doctor?
Call your doctor right away if you experience any sudden wheeziness, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body), chest pain, shortness of breath, nausea, or an irregular heartbeat.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Westfall TC, Westfall DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 282-87.
- Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 139.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 477.
- Teerlink JR, Sliwa Karen, Opie LH. Heart Failure. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 179-80.
- Drugs.com. Epinephrine Pregnancy and Breastfeeding Warnings. [Accessed 14 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Epinephrine. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
Marketer details
Name: Makcur Laboratories Ltd.
Address: CORPORATE OFFICE: No. 9/1, Magnet Corporate Park,Nr. Sola Bridge, Off. S.G.Highway, Ahmedabad – 380054 Gujarat.INDIA
Country of origin: India
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₹20.2
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1.0 ml in 1 vial
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