Makstat 40mg Tablet
Prescription Required
Product introduction
Makstat 40mg Tablet is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals that can appear around your joints leading to painful and swollen joints. This medicine helps to keep uric acid levels low.
Makstat 40mg Tablet can be taken with or without food. You should keep taking it as recommended by your doctor even when you are not having a gout attack. If you stop, your symptoms may get worse because of the formation of more crystals in your joints. You can help yourself by making some changes to your diet (eg. avoiding alcohol and non-vegetarian foods) and drinking plenty of fluids.
Some of the common side effects of this medicine are liver function abnormalities, nausea, joint pain, and rashes. You may experience a temporary increase in the gout symptoms (rapid onset of severe pain, warmth, and redness in the joint) when you first start taking the medicine. However, do not stop taking the medicine. Your doctor may suggest some painkillers and additional medicines to help reduce or prevent these symptoms. Tell your doctor right away if you get any symptoms of liver disease like persistent nausea, dark urine, or yellowing of the eyes or skin.
Before taking this medicine, let your doctor know if you have any heart problems, stroke, thyroid problems, or kidney or liver problems. If you are pregnant or breastfeeding, this medicine is best avoided. Check with your doctor. You will need regular blood tests while taking this medicine to check that your liver is working properly.
Uses of Makstat Tablet
Benefits of Makstat Tablet
In Treatment of Gout
Makstat 40mg Tablet is used to prevent and treat gout. Gout is caused by too much uric acid in your body. When the level becomes too high, crystals may form in and around certain joints and your kidneys. This can cause sudden and severe pain, redness, warmth, and swelling. This medicine works by preventing crystals from forming and reducing the levels of uric acid in your blood. This makes it less likely that you will suffer the symptoms and make them milder if you do have them. It is usually for long-term treatment and should be taken regularly until the dose is completed.
Side effects of Makstat Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Makstat
- Nausea
- Skin rash
- Abnormal liver function
- Joint pain
- Rash
How to use Makstat Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Makstat 40mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Makstat Tablet works
Makstat 40mg Tablet is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Makstat 40mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Makstat 40mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Makstat 40mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Makstat 40mg Tablet may cause side effects which could affect your ability to drive.
Makstat 40mg Tablet may cause dizziness, sleepiness, blurred vision, numbness or tingling sensation. This may affect your driving ability.
Makstat 40mg Tablet may cause dizziness, sleepiness, blurred vision, numbness or tingling sensation. This may affect your driving ability.
Kidney
CAUTION
Makstat 40mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Makstat 40mg Tablet may be needed. Please consult your doctor.
Limited information is available regarding the use of Makstat 40mg Tablet in these patients.
Limited information is available regarding the use of Makstat 40mg Tablet in these patients.
Liver
CAUTION
Makstat 40mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Makstat 40mg Tablet may be needed. Please consult your doctor.
Limited information is available regarding the use of Makstat 40mg Tablet in these patients.
Limited information is available regarding the use of Makstat 40mg Tablet in these patients.
What if you forget to take Makstat Tablet?
If you miss a dose of Makstat 40mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Makstat 40mg Tablet
₹8.42/Tablet
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Quick tips
- Your doctor has prescribed Makstat 40mg Tablet to reduce episodes of gout attack.
- Take it at the same time every day, with or without food.
- Take plenty of fluids (2-3 litres) daily while on Makstat 40mg Tablet.
- When you first start taking this medicine, you might have more gout attacks. Do not stop Makstat 40mg Tablet on having an acute attack of gout as that could make an attack worse.
- Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
- Stop taking this medicine and inform your doctor straight away if you have symptoms like rash, itchiness, difficulties in breathing, fever, or swelling of limbs or face.
Fact Box
Chemical Class
Thiazole Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Xanthine oxidase Inhibitors-gout
Interaction with drugs
Taking Makstat with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Febuxostat may raise blood levels of Rosuvastatin.
Do not consume Rosuvastatin with Febuxostat. If concurrent use is essential, watch out for symptoms such as unexplained muscle p
Febuxostat may raise blood levels of Aminophylline.
If concurrent use is essential, watch out for symptoms such as nausea, palpitations or headaches and consult your doctor if you
Febuxostat may raise blood levels of Aminophylline.
If concurrent use is essential, watch out for symptoms such as nausea, palpitations or headaches and consult your doctor if you
Febuxostat may raise blood levels of Azathioprine.
Do not consume Febuxostat with Azathioprine. If concurrent use is essential, watch out for symptoms such as abdominal pain, blur
Febuxostat may raise blood levels of Mercaptopurine.
Do not consume Febuxostat with Mercaptopurine. If concurrent use is essential, watch out for symptoms such as abdominal pain,
Patient concerns
FAQs
What is Makstat 40mg Tablet used for?
Makstat 40mg Tablet is used to treat gout in adults. It is mainly used in patients who did not respond to the treatment with allopurinol or who are not able to take allopurinol. Gout is a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints. It causes sudden attacks of redness, swelling, pain, and heat in one or more joints.
What are the side effects of Makstat 40mg Tablet?
Makstat 40mg Tablet may cause common side effects such as abnormal liver test results, diarrhea, headache, rash, nausea, and even an increase in gout symptoms and localized swelling due to retention of fluids in tissues (edema). Whereas, the serious side effects of Makstat 40mg Tablet include heart problems, gout flares, liver problems, and severe skin and allergic reactions. Immediately inform your doctor if you experience any serious side effects.
How long should I take Makstat 40mg Tablet?
The dose and duration of Makstat 40mg Tablet vary from person to person and are decided by your doctor. It may take several months before Makstat 40mg Tablet begins to prevent gout attacks. Do not stop taking Makstat 40mg Tablet without the advice of your doctor even if you feel better.
What is the best time to take Makstat 40mg Tablet?
Makstat 40mg Tablet is advised to be taken once a day. It can be taken at any time of the day, but preferably at the same time each day so that you remember to take it every day. This will help maintain the levels of Makstat 40mg Tablet in the body. You can take this medicine with or without food.
Can Makstat 40mg Tablet cause kidney damage?
Makstat 40mg Tablet may affect kidneys in different ways, though it is quite uncommon. You may experience blood in the urine, frequent urination, kidney stones, abnormal urine tests (increased level of proteins in the urine), and a reduction in the ability of the kidneys to function properly. Rarely, it may cause changes or decrease in urine amount due to inflammation in the kidneys (tubulointerstitial nephritis). Consult your doctor if your kidney functions get further affected.
Can I stop taking Makstat 40mg Tablet on my own if I am fine and have no pain or swelling in joints?
No, do not stop taking Makstat 40mg Tablet without your doctor's advice even if you feel better. Discontinuation of medicine may increase the levels of uric acid. It may also worsen your symptoms due to the formation of new crystals of urate in and around your joints and kidneys.
What are the things which I need to know while taking Makstat 40mg Tablet?
You should be aware that Makstat 40mg Tablet may cause serious heart problems which can be life-threatening in some cases. The symptoms of heart problems include chest pain, shortness of breath or trouble breathing, dizziness, fainting or feeling light-headed, rapid or irregular heartbeat. It may also cause numbness or weakness in one side of your body, slurring of speech and sudden blurry vision, or sudden severe headache. Immediately inform your doctor and seek medical help if you experience any of these symptoms.
Can Makstat 40mg Tablet cause any liver problems?
Yes, Makstat 40mg Tablet use may cause liver problems. Your doctor may advise you to get regular blood tests done before and during treatment with Makstat 40mg Tablet to check how well your liver was working before and while taking this medicine. Inform your doctor if you notice symptoms such as fatigue, pain, or tenderness on the right side of the abdomen or loss of appetite for several days or longer. It may also cause changes in the color of urine (dark or tea-colored) and may make your skin or the white part of your eyes turn yellow (jaundice).
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 997-98.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 534-35.
- Medscape. Febuxostat. [Accessed 02 Apr. 2019] (online) Available from:
- Febuxostat. Wooburn Green, Buckinghamshire: A. Menarini Farmaceutica Internazionale SRL; 2008 [revised 29 Oct. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
- Febuxostat. Deerfield, Illinois: Takeda Pharmaceuticals America, Inc.; 2009. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
- Febuxostat [Prescribing Information]. [Last Reviewed: Dec 2018]. [Accessed 24 June 2023]. (online) Available from:
Marketer details
Name: Trimak Lifesciences
Address: Kuldeep Nagar,Ambala cantt, Haryana-133004
Country of origin: India
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